Reactome | yORC4 [nucleoplasm]

yORC4 [nucleoplasm]

Stable Identifier

R-SCE-9749319

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

nucleoplasm

Synonyms

Origin recognition complex subunit 4, ORC4_YEAST

External Reference Information

External Reference

UniProt:P54791 ORC4

Gene Names

ORC4, YPR162C, P9325.5

Chain

chain:1-529

Reference Genes

BioGPS Gene:856291 ORC4

KEGG Gene (Saccharomyces cerevisiae (strain YJM789)):YPR162C ORC4

Monarch:856291 ORC4

NCBI Gene:856291 ORC4

Reference Transcript

RefSeq:NM_001184259.1 ORC4

Other Identifiers

1771620_at

7606_at

856291

GO:0000808

GO:0003674

GO:0003677

GO:0003688

GO:0005515

GO:0005575

GO:0005634

GO:0005654

GO:0005656

GO:0005664

GO:0005694

GO:0006260

GO:0006267

GO:0006270

GO:0006325

GO:0008150

GO:0030466

GO:0031261

Participates

as a component of

yORC(1-6) [nucleoplasm] (Saccharomyces cerevisiae)

Other forms of this molecule

ORC4 [nucleoplasm]

Cross References

RefSeq

NP_015488.1

OpenTargets

ENSG00000115947

PRO

P54791

PDB

6WGC, 5V8F, 6WGI, 5ZR1, 7MCA, 6RQC, 6WGG

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P54784 ORC1	6	phospho-PolyUb,p-S,T-ORC1 [cytosol] (R-SCE-9032195) phospho-PolyUb,p-S,T-ORC1 [nucleoplasm] (R-SCE-9032189) phospho-p-S,T-ORC1 [nucleoplasm] (R-SCE-68943) ORC1 [cytosol] (R-SCE-113840) yORC1 [nucleoplasm] (R-SCE-9749323) ORC1 [nucleoplasm] (R-SCE-68522)	0.822	18
UniProt:P50874 ORC5	2	yORC5 [nucleoplasm] (R-SCE-9749322) ORC5 [nucleoplasm] (R-SCE-68516)	0.788	21
UniProt:P54790 ORC3	2	yORC3 [nucleoplasm] (R-SCE-9749325) ORC3 [nucleoplasm] (R-SCE-68513)	0.678	9
UniProt:P32833 ORC2	2	yORC2 [nucleoplasm] (R-SCE-9749316) ORC2 [nucleoplasm] (R-SCE-68405)	0.669	9
UniProt:P09119 CDC6	4	phospho-p-CDC6 [cytosol] (R-SCE-68583) phospho-p-CDC6 [nucleoplasm] (R-SCE-5661317) yCDC6 [nucleoplasm] (R-SCE-9749328) CDC6 [nucleoplasm] (R-SCE-68542)	0.652	3
UniProt:P38826 ORC6	1	yORC6 [nucleoplasm] (R-SCE-9749321)	0.564	15
UniProt:Q08379 GOLGA2	3	p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179) GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) GOLGA2 [Golgi membrane] (R-HSA-6808764)	0.556	3

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