Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
phospho-p-S317,S345-CHEK1 [nucleoplasm]
Stable Identifier
R-SPO-113838
Type
Protein [EntityWithAccessionedSequence]
Species
Schizosaccharomyces pombe
Compartment
nucleoplasm
Synonyms
O14328
Locations in the PathwayBrowser
Expand all
Cell Cycle (Schizosaccharomyces pombe)
Cell Cycle Checkpoints (Schizosaccharomyces pombe)
G1/S DNA Damage Checkpoints (Schizosaccharomyces pombe)
p53-Independent G1/S DNA damage checkpoint (Schizosaccharomyces pombe)
p53-Independent DNA Damage Response (Schizosaccharomyces pombe)
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A (Schizosaccharomyces pombe)
Phosphorylation of Cdc25A at Ser-123 by Chk1 (Schizosaccharomyces pombe)
phospho-p-S317,S345-CHEK1 [nucleoplasm] (Schizosaccharomyces pombe)
G2/M Checkpoints (Schizosaccharomyces pombe)
Activation of ATR in response to replication stress (Schizosaccharomyces pombe)
Phosphorylation of Cdc25A at Ser-123 by Chk1 (Schizosaccharomyces pombe)
phospho-p-S317,S345-CHEK1 [nucleoplasm] (Schizosaccharomyces pombe)
Phosphorylation of Cdc25C at Ser 216 by Chk1 (Schizosaccharomyces pombe)
phospho-p-S317,S345-CHEK1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA Repair (Schizosaccharomyces pombe)
DNA Double-Strand Break Repair (Schizosaccharomyces pombe)
Homology Directed Repair (Schizosaccharomyces pombe)
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Schizosaccharomyces pombe)
HDR through Homologous Recombination (HRR) (Schizosaccharomyces pombe)
Homologous DNA Pairing and Strand Exchange (Schizosaccharomyces pombe)
Presynaptic phase of homologous DNA pairing and strand exchange (Schizosaccharomyces pombe)
CHEK1 phosphorylates RAD51 (Schizosaccharomyces pombe)
phospho-p-S317,S345-CHEK1 [nucleoplasm] (Schizosaccharomyces pombe)
External Reference Information
External Reference
UniProt:O14328
Reference Genes
BioGPS Gene:2539653
ENSEMBL:SPBC16E9.13
KEGG:spo:SPBC16E9.13
Monarch:2539653
NCBI Gene:2539653
PomBase:SPBC16E9.13
UCSC:O14328
Reference Transcript
RefSeq:NM_001021696.2
Other forms of this molecule
CHEK1 [cytosol]
CHEK1 [nucleoplasm]
Inferred From
p-S317,S345-CHEK1 [nucleoplasm]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 317 (in Homo sapiens)
Coordinate
317
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 345 (in Homo sapiens)
Coordinate
345
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
NP_595795.1
PRO
O14328
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text