Reactome | alpha-tubulin [cytosol]

alpha-tubulin [cytosol]

Stable Identifier

R-SPO-190587

Type

Set [CandidateSet]

Species

Schizosaccharomyces pombe

Compartment

cytosol

Locations in the PathwayBrowser

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Cell Cycle (Schizosaccharomyces pombe)

- Cell Cycle, Mitotic (Schizosaccharomyces pombe)
  - M Phase (Schizosaccharomyces pombe)
    - Mitotic Metaphase and Anaphase (Schizosaccharomyces pombe)
      - Mitotic Anaphase (Schizosaccharomyces pombe)
        
        Nuclear Envelope (NE) Reassembly (Schizosaccharomyces pombe)
        
        Sealing of the nuclear envelope (NE) by ESCRT-III (Schizosaccharomyces pombe)
        
        SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites (Schizosaccharomyces pombe)
        
        Microtubule [cytosol] (Schizosaccharomyces pombe)
        
        Microtubule protofilament [cytosol] (Schizosaccharomyces pombe)
        
        alpha-beta tubulin dimer [cytosol] (Schizosaccharomyces pombe)
        
        alpha-tubulin:GTP [cytosol] (Schizosaccharomyces pombe)
        
        alpha-tubulin [cytosol] (Schizosaccharomyces pombe)
        
        alpha-beta tubulin dimer [cytosol] (Schizosaccharomyces pombe)
        
        alpha-tubulin:GTP [cytosol] (Schizosaccharomyces pombe)
        
        alpha-tubulin [cytosol] (Schizosaccharomyces pombe)

Metabolism of proteins (Schizosaccharomyces pombe)

- Post-translational protein modification (Schizosaccharomyces pombe)
  - Asparagine N-linked glycosylation (Schizosaccharomyces pombe)
    - Transport to the Golgi and subsequent modification (Schizosaccharomyces pombe)
      - ER to Golgi Anterograde Transport (Schizosaccharomyces pombe)
        
        COPI-mediated anterograde transport (Schizosaccharomyces pombe)
        
        ERGIC-to-Golgi vesicles bind dynein:dynactin (Schizosaccharomyces pombe)
        
        Dynein:Dynactin:microtubule [cytosol] (Schizosaccharomyces pombe)
        
        Microtubule [cytosol] (Schizosaccharomyces pombe)
        
        Microtubule protofilament [cytosol] (Schizosaccharomyces pombe)
        
        alpha-beta tubulin dimer [cytosol] (Schizosaccharomyces pombe)
        
        alpha-tubulin:GTP [cytosol] (Schizosaccharomyces pombe)
        
        alpha-tubulin [cytosol] (Schizosaccharomyces pombe)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Schizosaccharomyces pombe)
        
        Dynein:Dynactin:microtubule [cytosol] (Schizosaccharomyces pombe)
        
        Microtubule [cytosol] (Schizosaccharomyces pombe)
        
        Microtubule protofilament [cytosol] (Schizosaccharomyces pombe)
        
        alpha-beta tubulin dimer [cytosol] (Schizosaccharomyces pombe)
        
        alpha-tubulin:GTP [cytosol] (Schizosaccharomyces pombe)
        
        alpha-tubulin [cytosol] (Schizosaccharomyces pombe)

Organelle biogenesis and maintenance (Schizosaccharomyces pombe)

- Cilium Assembly (Schizosaccharomyces pombe)
  - HDAC6 deacetylates microtubules (Schizosaccharomyces pombe)
    - Microtubule [cytosol] (Schizosaccharomyces pombe)
      - Microtubule protofilament [cytosol] (Schizosaccharomyces pombe)
        
        alpha-beta tubulin dimer [cytosol] (Schizosaccharomyces pombe)
        
        alpha-tubulin:GTP [cytosol] (Schizosaccharomyces pombe)
        
        alpha-tubulin [cytosol] (Schizosaccharomyces pombe)

Signal Transduction (Schizosaccharomyces pombe)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Schizosaccharomyces pombe)
  - Signaling by Rho GTPases (Schizosaccharomyces pombe)
    - RHO GTPase Effectors (Schizosaccharomyces pombe)
      - RHO GTPases activate IQGAPs (Schizosaccharomyces pombe)
        
        IQGAP1 binds CLIP1 and microtubules (Schizosaccharomyces pombe)
        
        Microtubule [cytosol] (Schizosaccharomyces pombe)
        
        Microtubule protofilament [cytosol] (Schizosaccharomyces pombe)
        
        alpha-beta tubulin dimer [cytosol] (Schizosaccharomyces pombe)
        
        alpha-tubulin:GTP [cytosol] (Schizosaccharomyces pombe)
        
        alpha-tubulin [cytosol] (Schizosaccharomyces pombe)
        
        RAC1,CDC42:GTP:IQGAP1:CLIP1:microtubule [plasma membrane] (Schizosaccharomyces pombe)
        
        Microtubule [cytosol] (Schizosaccharomyces pombe)
        
        Microtubule protofilament [cytosol] (Schizosaccharomyces pombe)
        
        alpha-beta tubulin dimer [cytosol] (Schizosaccharomyces pombe)
        
        alpha-tubulin:GTP [cytosol] (Schizosaccharomyces pombe)
        
        alpha-tubulin [cytosol] (Schizosaccharomyces pombe)

Vesicle-mediated transport (Schizosaccharomyces pombe)

- Membrane Trafficking (Schizosaccharomyces pombe)
  - ER to Golgi Anterograde Transport (Schizosaccharomyces pombe)
    - COPI-mediated anterograde transport (Schizosaccharomyces pombe)
      - ERGIC-to-Golgi vesicles bind dynein:dynactin (Schizosaccharomyces pombe)
        
        Dynein:Dynactin:microtubule [cytosol] (Schizosaccharomyces pombe)
        
        Microtubule [cytosol] (Schizosaccharomyces pombe)
        
        Microtubule protofilament [cytosol] (Schizosaccharomyces pombe)
        
        alpha-beta tubulin dimer [cytosol] (Schizosaccharomyces pombe)
        
        alpha-tubulin:GTP [cytosol] (Schizosaccharomyces pombe)
        
        alpha-tubulin [cytosol] (Schizosaccharomyces pombe)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Schizosaccharomyces pombe)
        
        Dynein:Dynactin:microtubule [cytosol] (Schizosaccharomyces pombe)
        
        Microtubule [cytosol] (Schizosaccharomyces pombe)
        
        Microtubule protofilament [cytosol] (Schizosaccharomyces pombe)
        
        alpha-beta tubulin dimer [cytosol] (Schizosaccharomyces pombe)
        
        alpha-tubulin:GTP [cytosol] (Schizosaccharomyces pombe)
        
        alpha-tubulin [cytosol] (Schizosaccharomyces pombe)

Participants

candidates

Participates

as a component of

alpha-tubulin:GTP [cytosol] (Schizosaccharomyces pombe)

Inferred From

alpha-tubulin [cytosol] (Homo sapiens)

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