Reactome | phospho-hta1 [nucleoplasm]

phospho-hta1 [nucleoplasm]

Stable Identifier

R-SPO-5683942

Type

Protein [EntityWithAccessionedSequence]

Species

Schizosaccharomyces pombe

Compartment

nucleoplasm

Synonyms

p-Y143-H2AFX, P04909

Locations in the PathwayBrowser

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DNA Repair (Schizosaccharomyces pombe)

- DNA Double-Strand Break Repair (Schizosaccharomyces pombe)
  - DNA Double Strand Break Response (Schizosaccharomyces pombe)
    - Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks (Schizosaccharomyces pombe)
      - ATM phosphorylates histone H2AFX on S139 at DNA DSBs (Schizosaccharomyces pombe)
        
        DNA DSBs:p-MRN:p-S-1981,Ac-K3016-ATM:KAT5:p-Y142-H2AFX-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
        
        p-Y142-H2AFX-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
        
        Homologues of p-Y143-H2AFX [nucleoplasm] (Schizosaccharomyces pombe)
        
        phospho-hta1 [nucleoplasm] (Schizosaccharomyces pombe)
      - ATM recognizes H2AFX-Nucleosomes (Schizosaccharomyces pombe)
        
        DNA DSBs:p-MRN:p-S-1981,Ac-K3016-ATM:KAT5:p-Y142-H2AFX-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
        
        p-Y142-H2AFX-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
        
        Homologues of p-Y143-H2AFX [nucleoplasm] (Schizosaccharomyces pombe)
        
        phospho-hta1 [nucleoplasm] (Schizosaccharomyces pombe)
        
        p-Y142-H2AFX-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
        
        Homologues of p-Y143-H2AFX [nucleoplasm] (Schizosaccharomyces pombe)
        
        phospho-hta1 [nucleoplasm] (Schizosaccharomyces pombe)

External Reference Information

External Reference

UniProt:P04909

Gene Names

hta1

Reference Genes

BioGPS Gene:2539499 hta1

ENSEMBL:SPCC622.08c

GeneDB:SPCC622.08c

KEGG Gene (Sc):SPCC622.08c hta1

Monarch:2539499 hta1

NCBI Gene:2539499 hta1

Reference Transcript

RefSeq:NM_001023170.2 hta1

Participant Of

hasMember

Homologues of p-Y143-H2AFX [nucleoplasm]

Other forms of this molecule

hta1 [nucleoplasm]

phospho-hta1 [nucleoplasm]

hta1 [nucleoplasm]

Inferred From

p-Y143-H2AFX [nucleoplasm] (Homo sapiens)

Modified Residues

Name

O4'-phospho-L-tyrosine at 143 (in Homo sapiens)

Coordinate

143

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

RefSeq

NP_588180.1

PRO

P04909