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RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm]
Stable Identifier
R-SSC-109909
Type
Complex
Species
Sus scrofa
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
DNA Repair (Sus scrofa)
Nucleotide Excision Repair (Sus scrofa)
Transcription-Coupled Nucleotide Excision Repair (TC-NER) (Sus scrofa)
Formation of TC-NER Pre-Incision Complex (Sus scrofa)
Active RNA Pol II complex transcribes lesion-containing DNA template (Sus scrofa)
Damaged dsDNA with open transcription bubble:Hyperphosphorylated RNA Pol II:TFIIH [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
ERCC8 (CSA) binds stalled RNA Pol II (Sus scrofa)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Sus scrofa)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Sus scrofa)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II (Sus scrofa)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Sus scrofa)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
RNA Pol II initiates transcription from damaged DNA template (Sus scrofa)
Damaged dsDNA with open transcription bubble:Hyperphosphorylated RNA Pol II:TFIIH [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
Gene expression (Transcription) (Sus scrofa)
RNA Polymerase II Transcription (Sus scrofa)
Generic Transcription Pathway (Sus scrofa)
Transcriptional Regulation by TP53 (Sus scrofa)
TP53 Regulates Transcription of DNA Repair Genes (Sus scrofa)
CCNK:CDK12 binds RNA Pol II at DNA repair genes (Sus scrofa)
CCNK:CDK12:Elongation Complex at DNA Repair Genes [nucleoplasm] (Sus scrofa)
Elongation Complex at DNA Repair Genes [nucleoplasm] (Sus scrofa)
Hyperphosphorylated RNA Pol II at DNA repair genes [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
Elongation Complex at DNA Repair Genes [nucleoplasm] (Sus scrofa)
Hyperphosphorylated RNA Pol II at DNA repair genes [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
CDK12 phosphorylates RNA Pol II CTD at DNA repair genes (Sus scrofa)
CCNK:CDK12:Elongation Complex at DNA Repair Genes [nucleoplasm] (Sus scrofa)
Elongation Complex at DNA Repair Genes [nucleoplasm] (Sus scrofa)
Hyperphosphorylated RNA Pol II at DNA repair genes [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
RNA Polymerase II Pre-transcription Events (Sus scrofa)
2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing (Sus scrofa)
Paused processive elongation complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
Processive elongation complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest (Sus scrofa)
Processive elongation complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
Abortive termination of elongation after arrest (Sus scrofa)
Aborted elongation complex after arrest [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
Processive elongation complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
Elongating transcript encounters a lesion in the template (Sus scrofa)
Processive elongation complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
Resumption of elongation after recovery from pausing (Sus scrofa)
Paused processive elongation complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
Processive elongation complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
TFIIS-mediated recovery of elongation from arrest (Sus scrofa)
Processive elongation complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
RNA Polymerase II Transcription Elongation (Sus scrofa)
Addition of nucleotides leads to transcript elongation (Sus scrofa)
Elongation complex [nucleoplasm] (Sus scrofa)
Early elongation complex with hyperphosphorylated Pol II CTD [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
Processive elongation complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
Formation of RNA Pol II elongation complex (Sus scrofa)
Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex (Sus scrofa)
Early elongation complex with hyperphosphorylated Pol II CTD [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
Recruitment of elongation factors to form elongation complex (Sus scrofa)
Early elongation complex with hyperphosphorylated Pol II CTD [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
Elongation complex [nucleoplasm] (Sus scrofa)
Early elongation complex with hyperphosphorylated Pol II CTD [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
Pol II elongation complex moves on the template as transcript elongates (Sus scrofa)
Elongation complex prior to separation [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
Processive elongation complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
Separation of elongating transcript from template (Sus scrofa)
Elongation complex prior to separation [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
Elongation complex with separated and uncleaved transcript [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
Metabolism of RNA (Sus scrofa)
Processing of Capped Intron-Containing Pre-mRNA (Sus scrofa)
Formation of pre-mRNPs (Sus scrofa)
capped, methylated pre-mRNA:CBC Complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Sus scrofa)
capped, methylated pre-mRNA:CBC Complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
Internal Methylation of mRNA (Sus scrofa)
capped, methylated pre-mRNA:CBC Complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
mRNA Splicing (Sus scrofa)
mRNA Splicing - Major Pathway (Sus scrofa)
Formation of the Spliceosomal Bact complex (Sus scrofa)
Spliceosomal B complex [nucleoplasm] (Sus scrofa)
capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Sus scrofa)
capped, methylated pre-mRNA:CBC Complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
Spliceosomal Bact complex [nucleoplasm] (Sus scrofa)
capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Sus scrofa)
capped, methylated pre-mRNA:CBC Complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
Formation of the Spliceosomal C* complex (Sus scrofa)
Spliceosomal C complex [nucleoplasm] (Sus scrofa)
mRNA intron lariat, 3'exon:RNA Polymerase II [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
Spliceosomal C* complex [nucleoplasm] (Sus scrofa)
mRNA intron lariat, 3'exon:RNA Polymerase II [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
Formation of the Spliceosomal E complex (Sus scrofa)
Spliceosomal E complex [nucleoplasm] (Sus scrofa)
capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Sus scrofa)
capped, methylated pre-mRNA:CBC Complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Sus scrofa)
capped, methylated pre-mRNA:CBC Complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
Formation of the Spliceosomal P complex and exon ligation (Sus scrofa)
Spliceosomal C* complex [nucleoplasm] (Sus scrofa)
mRNA intron lariat, 3'exon:RNA Polymerase II [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
Spliceosomal P complex [nucleoplasm] (Sus scrofa)
spliced mRNA:EJC:CBC complex:Alternative splicing factor [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
mRNA Splicing - Minor Pathway (Sus scrofa)
ATAC spliceosome mediated 3' splice site cleavage, exon ligation (Sus scrofa)
ATAC C Complex [nucleoplasm] (Sus scrofa)
capped, methylated pre-mRNA:CBC Complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
post exon ligation complex [nucleoplasm] (Sus scrofa)
capped, methylated pre-mRNA:CBC Complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
ATAC spliceosome mediated Lariat formation,5' splice site cleavage (Sus scrofa)
ATAC C Complex [nucleoplasm] (Sus scrofa)
capped, methylated pre-mRNA:CBC Complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
Formation of AT-AC B Complex (Sus scrofa)
ATAC A Complex [nucleoplasm] (Sus scrofa)
capped, methylated pre-mRNA:CBC Complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
ATAC B Complex [nucleoplasm] (Sus scrofa)
ATAC A Complex [nucleoplasm] (Sus scrofa)
capped, methylated pre-mRNA:CBC Complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
Formation of AT-AC C complex (Sus scrofa)
ATAC B Complex [nucleoplasm] (Sus scrofa)
ATAC A Complex [nucleoplasm] (Sus scrofa)
capped, methylated pre-mRNA:CBC Complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
ATAC C Complex [nucleoplasm] (Sus scrofa)
capped, methylated pre-mRNA:CBC Complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
Signal Transduction (Sus scrofa)
Signaling by Nuclear Receptors (Sus scrofa)
ESR-mediated signaling (Sus scrofa)
Estrogen-dependent gene expression (Sus scrofa)
p-TEFb phosphorylates serine 2 in RNA polymerase II CTD (Sus scrofa)
MYB gene:hyperphosphorylated RNA polymerase II:TFIIF:ESR1:ESTG:P-TEFb [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
phospho-POLR2A [nucleoplasm]
(Sus scrofa)
POLR2B [nucleoplasm]
(Sus scrofa)
POLR2C [nucleoplasm]
(Sus scrofa)
POLR2D [nucleoplasm]
(Sus scrofa)
POLR2E [nucleoplasm]
(Sus scrofa)
POLR2F [nucleoplasm]
(Sus scrofa)
POLR2G [nucleoplasm]
(Sus scrofa)
POLR2H [nucleoplasm]
(Sus scrofa)
POLR2I [nucleoplasm]
(Sus scrofa)
POLR2J [nucleoplasm]
(Sus scrofa)
POLR2K [nucleoplasm]
(Sus scrofa)
POLR2L [nucleoplasm]
(Sus scrofa)
Participates
as an output of
Elongating transcript encounters a lesion in the template (Sus scrofa)
as a component of
Aborted elongation complex after arrest [nucleoplasm] (Sus scrofa)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Sus scrofa)
Damaged dsDNA with open transcription bubble:Hyperphosphorylated RNA Pol II:TFIIH [nucleoplasm] (Sus scrofa)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Sus scrofa)
Inferred From
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm]
(Homo sapiens)
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