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CHEK1 [nucleoplasm]
Stable Identifier
R-SSC-113826
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
nucleoplasm
Synonyms
F1S774
Locations in the PathwayBrowser
Expand all
Cell Cycle (Sus scrofa)
Cell Cycle Checkpoints (Sus scrofa)
G2/M Checkpoints (Sus scrofa)
Activation of ATR in response to replication stress (Sus scrofa)
Recruitment and activation of Chk1 (Sus scrofa)
CHEK1 [nucleoplasm] (Sus scrofa)
G2/M DNA damage checkpoint (Sus scrofa)
Recruitment and activation of Chk1 (Sus scrofa)
CHEK1 [nucleoplasm] (Sus scrofa)
DNA Repair (Sus scrofa)
DNA Double-Strand Break Repair (Sus scrofa)
Homology Directed Repair (Sus scrofa)
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Sus scrofa)
Processing of DNA double-strand break ends (Sus scrofa)
Activation of CHEK1 at resected DNA DSBs (Sus scrofa)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1:TIMELESS:TIPIN:p-T916,S945-CLSPN:CHEK1 [nucleoplasm] (Sus scrofa)
CHEK1 [nucleoplasm] (Sus scrofa)
CHEK1 is recruited to resected DNA DSBs (Sus scrofa)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1:TIMELESS:TIPIN:p-T916,S945-CLSPN:CHEK1 [nucleoplasm] (Sus scrofa)
CHEK1 [nucleoplasm] (Sus scrofa)
CHEK1 [nucleoplasm] (Sus scrofa)
External Reference Information
External Reference
UniProt:F1S774
Reference Genes
BioGPS Gene:100511709
ENSEMBL:ENSSSCG00000015215.5
ENSEMBL:ENSSSCG00005040954.1
KEGG Gene (Sus scrofa):100511709
Monarch:100511709
NCBI Gene:100511709
Reference Transcript
RefSeq:XM_005667481.2
RefSeq:XM_013979544.1
Other Identifiers
100511709
GO:0000077
GO:0000086
GO:0000228
GO:0000278
GO:0000781
GO:0000785
GO:0000794
GO:0001833
GO:0003824
GO:0004672
GO:0004674
GO:0005634
GO:0005654
GO:0005657
GO:0005694
GO:0005737
GO:0005813
GO:0005815
GO:0005856
GO:0006281
GO:0006310
GO:0006325
GO:0006338
GO:0006915
GO:0006974
GO:0006997
GO:0007010
GO:0007095
GO:0010468
GO:0010569
GO:0012501
GO:0016740
GO:0019904
GO:0023052
GO:0032991
GO:0035402
GO:0042127
GO:0042770
GO:0043226
GO:0043231
GO:0044818
GO:0045787
GO:0045814
GO:0045839
GO:0046602
GO:0048856
GO:0071260
GO:0140014
GO:0140096
GO:1902742
Ssc.25040.1.S1_at
Ssc.29650.1.A1_at
Participates
as an input of
Recruitment and activation of Chk1 (Sus scrofa)
CHEK1 is recruited to resected DNA DSBs (Sus scrofa)
as a component of
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1:TIMELESS:TIPIN:p-T916,S945-CLSPN:CHEK1 [nucleoplasm] (Sus scrofa)
Other forms of this molecule
CHEK1 [cytosol]
phospho-p-S317,S345-CHEK1 [nucleoplasm]
Inferred From
CHEK1 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
XP_013834998.1
,
XP_005667538.1
Ensembl
ENSSSCT00000016581
,
ENSSSCG00000015215
,
ENSSSCP00000016136
VGNC
86637
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