Reactome | phospho-CLSPN [nucleoplasm]

phospho-CLSPN [nucleoplasm]

Stable Identifier

R-SSC-176296

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

nucleoplasm

Synonyms

p-T916,S945-CLSPN, A0A286ZLZ9

Locations in the PathwayBrowser

Expand all

Cell Cycle (Sus scrofa)

- Cell Cycle Checkpoints (Sus scrofa)
  - G2/M Checkpoints (Sus scrofa)
    - Activation of ATR in response to replication stress (Sus scrofa)
      - Activation of claspin (Sus scrofa)
        
        Cdc45:CDK:DDK:Mcm10:Activated claspin:pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        phospho-CLSPN [nucleoplasm] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A286ZLZ9

Gene Names

CLSPN

Reference Genes

ENSEMBL:ENSSSCG00000003628.5

Other Identifiers

100525928

GO:0000076

GO:0000077

GO:0000217

GO:0000278

GO:0003677

GO:0005634

GO:0005654

GO:0005794

GO:0007095

GO:0010997

GO:0023052

GO:0033314

GO:0043226

Ssc.19346.1.S1_at

Ssc.21360.1.A1_at

Participates

as a component of

as an output of

Activation of CHEK1 at resected DNA DSBs (Sus scrofa)

as an input of

CHEK1 is recruited to resected DNA DSBs (Sus scrofa)

Other forms of this molecule

CLSPN [nucleoplasm]

Inferred From

p-T916,S945-CLSPN [nucleoplasm] (Homo sapiens)

Modified Residues

Name

O-phospho-L-serine at 945 (in Homo sapiens)

Coordinate

945

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Name

O-phospho-L-threonine at 916 (in Homo sapiens)

Coordinate

916

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Cross References

OpenTargets

ENSG00000092853

Ensembl

ENSSSCP00000032585, ENSSSCT00000042351, ENSSSCG00000003628

VGNC

86783

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