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NFKB1(1-433), NFKB2(1-454):RELA [nucleoplasm]
Stable Identifier
R-SSC-177673
Type
Complex
Species
Sus scrofa
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Chromatin organization (Sus scrofa)
Chromatin modifying enzymes (Sus scrofa)
PKMTs methylate histone lysines (Sus scrofa)
SETD6 methylates RELA in the NFkB complex (Sus scrofa)
NFKB1(1-433), NFKB2(1-454):RELA [nucleoplasm] (Sus scrofa)
Immune System (Sus scrofa)
Cytokine Signaling in Immune system (Sus scrofa)
Signaling by Interleukins (Sus scrofa)
Interleukin-1 family signaling (Sus scrofa)
Interleukin-1 processing (Sus scrofa)
Interleukin-1 family precursors are cleaved by caspase-1 (Sus scrofa)
NFKB1(1-433), NFKB2(1-454):RELA [nucleoplasm] (Sus scrofa)
Interleukin-1 signaling (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
NF-kappa-B complex is transported from cytosol to nucleus (Sus scrofa)
NFKB1(1-433), NFKB2(1-454):RELA [nucleoplasm] (Sus scrofa)
Innate Immune System (Sus scrofa)
Cytosolic sensors of pathogen-associated DNA (Sus scrofa)
DEx/H-box helicases activate type I IFN and inflammatory cytokines production (Sus scrofa)
NFkB complex translocates from the cytosol to the nucleus (Sus scrofa)
NFKB1(1-433), NFKB2(1-454):RELA [nucleoplasm] (Sus scrofa)
ZBP1(DAI) mediated induction of type I IFNs (Sus scrofa)
RIP-mediated NFkB activation via ZBP1 (Sus scrofa)
NFkB complex translocates from the cytosol to the nucleus (Sus scrofa)
NFKB1(1-433), NFKB2(1-454):RELA [nucleoplasm] (Sus scrofa)
DDX58/IFIH1-mediated induction of interferon-alpha/beta (Sus scrofa)
TRAF6 mediated NF-kB activation (Sus scrofa)
NF-kappa-B complex is transported from cytosol to nucleus (Sus scrofa)
NFKB1(1-433), NFKB2(1-454):RELA [nucleoplasm] (Sus scrofa)
Toll-like Receptor Cascades (Sus scrofa)
Toll Like Receptor 10 (TLR10) Cascade (Sus scrofa)
MyD88 cascade initiated on plasma membrane (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
NF-kappa-B complex is transported from cytosol to nucleus (Sus scrofa)
NFKB1(1-433), NFKB2(1-454):RELA [nucleoplasm] (Sus scrofa)
Toll Like Receptor 2 (TLR2) Cascade (Sus scrofa)
Toll Like Receptor TLR1:TLR2 Cascade (Sus scrofa)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
NF-kappa-B complex is transported from cytosol to nucleus (Sus scrofa)
NFKB1(1-433), NFKB2(1-454):RELA [nucleoplasm] (Sus scrofa)
Toll Like Receptor TLR6:TLR2 Cascade (Sus scrofa)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
NF-kappa-B complex is transported from cytosol to nucleus (Sus scrofa)
NFKB1(1-433), NFKB2(1-454):RELA [nucleoplasm] (Sus scrofa)
Toll Like Receptor 3 (TLR3) Cascade (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
NF-kappa-B complex is transported from cytosol to nucleus (Sus scrofa)
NFKB1(1-433), NFKB2(1-454):RELA [nucleoplasm] (Sus scrofa)
Toll Like Receptor 4 (TLR4) Cascade (Sus scrofa)
MyD88-independent TLR4 cascade (Sus scrofa)
TRIF (TICAM1)-mediated TLR4 signaling (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
NF-kappa-B complex is transported from cytosol to nucleus (Sus scrofa)
NFKB1(1-433), NFKB2(1-454):RELA [nucleoplasm] (Sus scrofa)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
NF-kappa-B complex is transported from cytosol to nucleus (Sus scrofa)
NFKB1(1-433), NFKB2(1-454):RELA [nucleoplasm] (Sus scrofa)
Toll Like Receptor 5 (TLR5) Cascade (Sus scrofa)
MyD88 cascade initiated on plasma membrane (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
NF-kappa-B complex is transported from cytosol to nucleus (Sus scrofa)
NFKB1(1-433), NFKB2(1-454):RELA [nucleoplasm] (Sus scrofa)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Sus scrofa)
MyD88 dependent cascade initiated on endosome (Sus scrofa)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
NF-kappa-B complex is transported from cytosol to nucleus (Sus scrofa)
NFKB1(1-433), NFKB2(1-454):RELA [nucleoplasm] (Sus scrofa)
Toll Like Receptor 9 (TLR9) Cascade (Sus scrofa)
MyD88 dependent cascade initiated on endosome (Sus scrofa)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
NF-kappa-B complex is transported from cytosol to nucleus (Sus scrofa)
NFKB1(1-433), NFKB2(1-454):RELA [nucleoplasm] (Sus scrofa)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
Nuclear factor NF-kappa-B p50 [nucleoplasm]
(Sus scrofa)
RELA [nucleoplasm]
(Sus scrofa)
Participates
as an input of
SETD6 methylates RELA in the NFkB complex (Sus scrofa)
as an output of
NFkB complex translocates from the cytosol to the nucleus (Sus scrofa)
NF-kappa-B complex is transported from cytosol to nucleus (Sus scrofa)
This entity regulates
Positively
Interleukin-1 family precursors are cleaved by caspase-1
(Sus scrofa)
Inferred From
NFKB1(1-433), NFKB2(1-454):RELA [nucleoplasm]
(Homo sapiens)
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