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EGFR [plasma membrane]
Stable Identifier
R-SSC-179837
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
plasma membrane
Synonyms
A0A5G2QBP1
Locations in the PathwayBrowser
Expand all
Signal Transduction (Sus scrofa)
Signaling by GPCR (Sus scrofa)
GPCR downstream signalling (Sus scrofa)
G alpha (q) signalling events (Sus scrofa)
Gastrin-CREB signalling pathway via PKC and MAPK (Sus scrofa)
EGFR Transactivation by Gastrin (Sus scrofa)
Mature HBEGF binds to EGFR, triggering dimerisation and autophosphorylation of the receptor (Sus scrofa)
EGFR [plasma membrane] (Sus scrofa)
Signaling by Non-Receptor Tyrosine Kinases (Sus scrofa)
Signaling by PTK6 (Sus scrofa)
PTK6 promotes HIF1A stabilization (Sus scrofa)
EGFR phosphorylates GPNMB (Sus scrofa)
HBEGF:EGFR:GPNMB [plasma membrane] (Sus scrofa)
HBEGF:EGFR [plasma membrane] (Sus scrofa)
EGFR [plasma membrane] (Sus scrofa)
HBEGF:EGFR:p-Y525-GPNMB [plasma membrane] (Sus scrofa)
HBEGF:EGFR [plasma membrane] (Sus scrofa)
EGFR [plasma membrane] (Sus scrofa)
HBEGF-bound EGFR forms a heterodimer with GPNMB (Sus scrofa)
HBEGF:EGFR [plasma membrane] (Sus scrofa)
EGFR [plasma membrane] (Sus scrofa)
HBEGF:EGFR:GPNMB [plasma membrane] (Sus scrofa)
HBEGF:EGFR [plasma membrane] (Sus scrofa)
EGFR [plasma membrane] (Sus scrofa)
LINC01139 facilitates PTK6 autophosphorylation (Sus scrofa)
HBEGF:EGFR:p-Y525-GPNMB:LINC01139:PTK6:LRRK2 [plasma membrane] (Sus scrofa)
HBEGF:EGFR:p-Y525-GPNMB [plasma membrane] (Sus scrofa)
HBEGF:EGFR [plasma membrane] (Sus scrofa)
EGFR [plasma membrane] (Sus scrofa)
HBEGF:EGFR:p-Y525-GPNMB:LINC01139:p-Y351-PTK6:LRRK2 [plasma membrane] (Sus scrofa)
HBEGF:EGFR:p-Y525-GPNMB [plasma membrane] (Sus scrofa)
HBEGF:EGFR [plasma membrane] (Sus scrofa)
EGFR [plasma membrane] (Sus scrofa)
LINC01139 promotes phosphorylation of HIF1A by LRRK2 (Sus scrofa)
HBEGF:EGFR:p-Y525-GPNMB:LINC01139:p-Y351-PTK6:LRRK2 [plasma membrane] (Sus scrofa)
HBEGF:EGFR:p-Y525-GPNMB [plasma membrane] (Sus scrofa)
HBEGF:EGFR [plasma membrane] (Sus scrofa)
EGFR [plasma membrane] (Sus scrofa)
LINC01139 promotes phosphorylation of HIF1A by PTK6 (Sus scrofa)
HBEGF:EGFR:p-Y525-GPNMB:LINC01139:p-Y351-PTK6:LRRK2 [plasma membrane] (Sus scrofa)
HBEGF:EGFR:p-Y525-GPNMB [plasma membrane] (Sus scrofa)
HBEGF:EGFR [plasma membrane] (Sus scrofa)
EGFR [plasma membrane] (Sus scrofa)
Signaling by Receptor Tyrosine Kinases (Sus scrofa)
Signaling by EGFR (Sus scrofa)
AAMP binds EGFR (Sus scrofa)
EGFR [plasma membrane] (Sus scrofa)
EGFR:AAMP [plasma membrane] (Sus scrofa)
EGFR [plasma membrane] (Sus scrofa)
EGFR autophosphorylation (Sus scrofa)
EGF-like ligands:EGFR dimer [plasma membrane] (Sus scrofa)
EGFR:EGF-like ligands [plasma membrane] (Sus scrofa)
EGFR [plasma membrane] (Sus scrofa)
EGFR [plasma membrane] (Sus scrofa)
EGFR:FAM83B,(FAM83A, FAM83D) [plasma membrane] (Sus scrofa)
EGFR [plasma membrane] (Sus scrofa)
EGFR binds EGF ligand (Sus scrofa)
EGFR [plasma membrane] (Sus scrofa)
EGFR:EGF-like ligands [plasma membrane] (Sus scrofa)
EGFR [plasma membrane] (Sus scrofa)
EGFR dimerization (Sus scrofa)
EGF-like ligands:EGFR dimer [plasma membrane] (Sus scrofa)
EGFR:EGF-like ligands [plasma membrane] (Sus scrofa)
EGFR [plasma membrane] (Sus scrofa)
EGFR:AAMP [plasma membrane] (Sus scrofa)
EGFR [plasma membrane] (Sus scrofa)
EGFR:EGF-like ligands [plasma membrane] (Sus scrofa)
EGFR [plasma membrane] (Sus scrofa)
EGFR downregulation (Sus scrofa)
EGFR phosphorylates EPS15 (Sus scrofa)
EGFR [plasma membrane] (Sus scrofa)
Phosphorylation of CBL (EGFR:CBL) (Sus scrofa)
EGFR [plasma membrane] (Sus scrofa)
Phosphorylation of CBL (EGFR:GRB2:CBL) (Sus scrofa)
EGFR [plasma membrane] (Sus scrofa)
FAM83B, (FAM83A, FAM83D) bind EGFR (Sus scrofa)
EGFR [plasma membrane] (Sus scrofa)
EGFR:FAM83B,(FAM83A, FAM83D) [plasma membrane] (Sus scrofa)
EGFR [plasma membrane] (Sus scrofa)
Phosphorylation of EGFR by SRC kinase (Sus scrofa)
EGF-like ligands:EGFR dimer [plasma membrane] (Sus scrofa)
EGFR:EGF-like ligands [plasma membrane] (Sus scrofa)
EGFR [plasma membrane] (Sus scrofa)
SHC1 events in EGFR signaling (Sus scrofa)
SHC1 phosphorylation by phosphorylated EGFR (Sus scrofa)
EGFR [plasma membrane] (Sus scrofa)
Signaling by ERBB2 (Sus scrofa)
SRC family kinases phosphorylate ERBB2 (Sus scrofa)
ERBB2 heterodimers [plasma membrane] (Sus scrofa)
EGF:EGFR:ERBB2 [plasma membrane] (Sus scrofa)
EGF:EGFR [plasma membrane] (Sus scrofa)
EGFR [plasma membrane] (Sus scrofa)
p-Y877-ERBB2 heterodimers [plasma membrane] (Sus scrofa)
EGF:EGFR:p-Y877-ERBB2 [plasma membrane] (Sus scrofa)
EGF:EGFR [plasma membrane] (Sus scrofa)
EGFR [plasma membrane] (Sus scrofa)
Trans-autophosphorylation of ERBB2 heterodimers (Sus scrofa)
ERBB2 heterodimers [plasma membrane] (Sus scrofa)
EGF:EGFR:ERBB2 [plasma membrane] (Sus scrofa)
EGF:EGFR [plasma membrane] (Sus scrofa)
EGFR [plasma membrane] (Sus scrofa)
Trans-autophosphorylation of p-Y877-ERBB2 heterodimers (Sus scrofa)
p-Y877-ERBB2 heterodimers [plasma membrane] (Sus scrofa)
EGF:EGFR:p-Y877-ERBB2 [plasma membrane] (Sus scrofa)
EGF:EGFR [plasma membrane] (Sus scrofa)
EGFR [plasma membrane] (Sus scrofa)
Signaling by ERBB4 (Sus scrofa)
ERBB4 forms heterodimers with EGFR (Sus scrofa)
EGF:EGFR [plasma membrane] (Sus scrofa)
EGFR [plasma membrane] (Sus scrofa)
ERBB4:EGFR heterodimer [plasma membrane] (Sus scrofa)
EGF:EGFR [plasma membrane] (Sus scrofa)
EGFR [plasma membrane] (Sus scrofa)
External Reference Information
External Reference
UniProt:A0A5G2QBP1
Reference Genes
ENSEMBL:ENSSSCG00000022126.4
Other Identifiers
397070
GO:0000166
GO:0000278
GO:0001934
GO:0003682
GO:0003824
GO:0004672
GO:0004713
GO:0004714
GO:0004888
GO:0005006
GO:0005524
GO:0005634
GO:0005737
GO:0005768
GO:0005886
GO:0006260
GO:0006281
GO:0006351
GO:0006355
GO:0007155
GO:0007165
GO:0007166
GO:0007169
GO:0007173
GO:0008092
GO:0008284
GO:0009986
GO:0010008
GO:0012501
GO:0016020
GO:0016301
GO:0016310
GO:0016323
GO:0016740
GO:0019899
GO:0019900
GO:0019903
GO:0023052
GO:0030054
GO:0030154
GO:0030163
GO:0030296
GO:0030307
GO:0030335
GO:0031410
GO:0031625
GO:0031901
GO:0032587
GO:0032991
GO:0033138
GO:0034614
GO:0036211
GO:0038127
GO:0038134
GO:0042127
GO:0042177
GO:0042327
GO:0042802
GO:0043066
GO:0043226
GO:0043235
GO:0045121
GO:0045739
GO:0045740
GO:0045893
GO:0045944
GO:0046328
GO:0048471
GO:0048856
GO:0048870
GO:0050679
GO:0050730
GO:0051015
GO:0051896
GO:0051897
GO:0060089
GO:0070141
GO:0070372
GO:0070374
GO:0071276
GO:0071392
GO:0072659
GO:0090263
GO:0097489
GO:0097708
GO:0098590
GO:0098609
GO:0098772
GO:0140096
GO:1900087
GO:1901224
GO:1902895
GO:1903078
GO:1905208
Ssc.55.1.S1_at
Participates
as a component of
HBEGF:EGFR [plasma membrane] (Sus scrofa)
EGF:EGFR [plasma membrane] (Sus scrofa)
EGFR:FAM83B,(FAM83A, FAM83D) [plasma membrane] (Sus scrofa)
EGFR:AAMP [plasma membrane] (Sus scrofa)
EGFR:EGF-like ligands [plasma membrane] (Sus scrofa)
as an input of
Mature HBEGF binds to EGFR, triggering dimerisation and autophosphorylation of the receptor (Sus scrofa)
FAM83B, (FAM83A, FAM83D) bind EGFR (Sus scrofa)
EGFR binds EGF ligand (Sus scrofa)
AAMP binds EGFR (Sus scrofa)
Other forms of this molecule
phospho-p-6Y-EGFR [clathrin-coated endocytic vesicle membrane]
phospho-p-4Y-EGFR [plasma membrane]
phospho-p-Y1016,Y1069,Y1092,Y1110,Y1197-EGFR [plasma membrane]
phospho-p-Y1086,Y1101-EGFR [plasma membrane]
phospho-p-6Y-EGFR [plasma membrane]
Inferred From
EGFR [plasma membrane]
(Homo sapiens)
Cross References
Ensembl
ENSSSCP00000061918
,
ENSSSCT00000069349
,
ENSSSCG00000022126
VGNC
87587
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