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phospho-p-Y55-SPRY2 [cytosol]
Stable Identifier
R-SSC-182950
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
cytosol
Synonyms
F1RP67
Locations in the PathwayBrowser
Expand all
Signal Transduction (Sus scrofa)
Signaling by Receptor Tyrosine Kinases (Sus scrofa)
Signaling by EGFR (Sus scrofa)
EGFR downregulation (Sus scrofa)
CBL binds and ubiquitinates phosphorylated Sprouty (Sus scrofa)
EGF-like ligands:p-6Y-EGFR:CBL:Ub-p-Y53/55-SPRY1/2 [plasma membrane] (Sus scrofa)
Ub-p-Y53/55-SPRY1/2 [cytosol] (Sus scrofa)
p-Y53/55-SPRY1/2 [cytosol] (Sus scrofa)
phospho-p-Y55-SPRY2 [cytosol] (Sus scrofa)
CBL ubiquitinates Sprouty (Sus scrofa)
EGF-like ligands:p-6Y-EGFR:CBL:Ub-p-Y53/55-SPRY1/2 [plasma membrane] (Sus scrofa)
Ub-p-Y53/55-SPRY1/2 [cytosol] (Sus scrofa)
p-Y53/55-SPRY1/2 [cytosol] (Sus scrofa)
phospho-p-Y55-SPRY2 [cytosol] (Sus scrofa)
EGF-like ligands:p-6Y-EGFR:CBL:p-Y53/55-SPRY1/2 [plasma membrane] (Sus scrofa)
p-Y53/55-SPRY1/2 [cytosol] (Sus scrofa)
phospho-p-Y55-SPRY2 [cytosol] (Sus scrofa)
Sprouty lures CBL away from EGFR (Sus scrofa)
phospho-p-Y55-SPRY2 [cytosol] (Sus scrofa)
External Reference Information
External Reference
UniProt:F1RP67
Reference Genes
BioGPS Gene:100157266
ENSEMBL:ENSSSCG00000009482.4
ENSEMBL:ENSSSCG00005029787.1
KEGG Gene (Sus scrofa):100157266
Monarch:100157266
NCBI Gene:100157266
Reference Transcript
RefSeq:XM_001927097.4
Other Identifiers
100157266
GO:0000132
GO:0000278
GO:0005634
GO:0005829
GO:0005856
GO:0007010
GO:0007163
GO:0007275
GO:0007605
GO:0008285
GO:0008543
GO:0009966
GO:0010628
GO:0010719
GO:0010801
GO:0012501
GO:0015629
GO:0015630
GO:0016020
GO:0016525
GO:0019901
GO:0023052
GO:0030154
GO:0030324
GO:0030335
GO:0030512
GO:0031345
GO:0031397
GO:0033138
GO:0035924
GO:0036211
GO:0040037
GO:0042472
GO:0043066
GO:0043226
GO:0043539
GO:0045165
GO:0045742
GO:0046580
GO:0048754
GO:0048856
GO:0048870
GO:0050877
GO:0051387
GO:0051897
GO:0055105
GO:0060425
GO:0060437
GO:0060449
GO:0060541
GO:0070371
GO:0070373
GO:0070374
GO:0098772
GO:0140678
GO:1900747
GO:1902747
GO:1990752
GO:1990830
Participates
as an input of
Sprouty lures CBL away from EGFR (Sus scrofa)
as a member of
p-Y53/55-SPRY1/2 [cytosol] (Sus scrofa)
Other forms of this molecule
phospho-p-S111,S120-SPRY2 [cytosol]
phospho-p-S112,S121-SPRY2 [plasma membrane]
phospho-p-Y55,Y227-SPRY2 [plasma membrane]
phospho-p-S112,S115-SPRY2 [cytosol]
SPRY2 [cytosol]
SPRY2 [plasma membrane]
Inferred From
p-Y55-SPRY2 [cytosol]
(Homo sapiens)
Modified Residues
Name
O4'-phospho-L-tyrosine at 55 (in Homo sapiens)
Coordinate
55
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
RefSeq
XP_001927132.1
Ensembl
ENSSSCP00000069477
,
ENSSSCG00000009482
,
ENSSSCT00000085294
VGNC
93425
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