Reactome | phospho-FOXO3 [nucleoplasm]

phospho-FOXO3 [nucleoplasm]

Stable Identifier

R-SSC-199289

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

nucleoplasm

Synonyms

p-T32,S253,S315-FOXO3, F1RT23

Locations in the PathwayBrowser

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Gene expression (Transcription) (Sus scrofa)

- RNA Polymerase II Transcription (Sus scrofa)
  - Generic Transcription Pathway (Sus scrofa)
    - FOXO-mediated transcription (Sus scrofa)
      - Regulation of localization of FOXO transcription factors (Sus scrofa)
        
        AKT-phosphorylated FOXO1,FOXO3,FOXO4 translocate to the cytosol (Sus scrofa)
        
        p-T24,S256,S319-FOXO1,p-T32,S253,S315-FOXO3,p-T32,S197,S262-FOXO4,(p-T26,S184-FOXO6) [nucleoplasm] (Sus scrofa)
        
        phospho-FOXO3 [nucleoplasm] (Sus scrofa)

External Reference Information

External Reference

UniProt:F1RT23

Gene Names

FOXO3

Reference Genes

ENSEMBL:ENSSSCG00000004387

Other Identifiers

733621

GO:0000003

GO:0000122

GO:0000976

GO:0000978

GO:0000981

GO:0001227

GO:0001228

GO:0001542

GO:0001544

GO:0001547

GO:0001556

GO:0003674

GO:0003677

GO:0003700

GO:0005575

GO:0005622

GO:0005634

GO:0005737

GO:0005739

GO:0005741

GO:0005759

GO:0005829

GO:0006355

GO:0006357

GO:0006390

GO:0006914

GO:0006950

GO:0007165

GO:0007267

GO:0008134

GO:0008150

GO:0008219

GO:0008283

GO:0008286

GO:0009056

GO:0009058

GO:0010508

GO:0014737

GO:0016020

GO:0021700

GO:0030154

GO:0030330

GO:0031490

GO:0032991

GO:0034246

GO:0034599

GO:0034641

GO:0040007

GO:0042592

GO:0042593

GO:0042594

GO:0043226

GO:0043565

GO:0045893

GO:0045944

GO:0048854

GO:0048856

GO:0090090

GO:0097150

GO:0097192

GO:1902895

GO:2000177

GO:2000377

Ssc.20531.1.S1_at

Ssc.2488.2.S1_at

Ssc.2943.1.A1_at

Participant Of

input

AKT-phosphorylated FOXO3 translocates to cytosol

hasMember

p-T24,S256,S319-FOXO1,p-T32,S253,S315-FOXO3,p-T32,S197,S262-FOXO4,(p-T26,S184-FOXO6) [nucleoplasm]

Other forms of this molecule

phospho-FOXO3 [nucleoplasm]

phospho-FOXO3 [cytosol]

FOXO3 [cytosol]

FOXO3 [nucleoplasm]

phospho-FOXO3 [cytosol]

FOXO3 [nucleoplasm]

Inferred From

p-T32,S253,S315-FOXO3 [nucleoplasm] (Homo sapiens)

Modified Residues

Name

O-phospho-L-serine at 253 (in Homo sapiens)

Coordinate

253

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Name

O-phospho-L-serine at 315 (in Homo sapiens)

Coordinate

315

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Name

O-phospho-L-threonine at 32 (in Homo sapiens)

Coordinate

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Cross References

OpenTargets

ENSG00000118689

Ensembl

ENSSSCP00000004735, ENSSSCG00000004387, ENSSSCT00000004849

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