Reactome | DUSP7 [nucleoplasm]

DUSP7 [nucleoplasm]

Stable Identifier

R-SSC-203791

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

nucleoplasm

Synonyms

DUSP7, F1SIY1

Locations in the PathwayBrowser

Expand all

Immune System (Sus scrofa)

- Cytokine Signaling in Immune system (Sus scrofa)
  - Signaling by Interleukins (Sus scrofa)
    - Interleukin-17 signaling (Sus scrofa)
      - MAP kinase activation (Sus scrofa)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Sus scrofa)
        
        ERK/MAPK targets (Sus scrofa)
        
        ERKs are inactivated (Sus scrofa)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Sus scrofa)
        
        ERK-specific DUSP [nucleoplasm] (Sus scrofa)
        
        DUSP7 [nucleoplasm] (Sus scrofa)
- Innate Immune System (Sus scrofa)
  - Toll-like Receptor Cascades (Sus scrofa)
    - Toll Like Receptor 10 (TLR10) Cascade (Sus scrofa)
      - MyD88 cascade initiated on plasma membrane (Sus scrofa)
        
        MAP kinase activation (Sus scrofa)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Sus scrofa)
        
        ERK/MAPK targets (Sus scrofa)
        
        ERKs are inactivated (Sus scrofa)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Sus scrofa)
        
        ERK-specific DUSP [nucleoplasm] (Sus scrofa)
        
        DUSP7 [nucleoplasm] (Sus scrofa)
    - Toll Like Receptor 2 (TLR2) Cascade (Sus scrofa)
      - Toll Like Receptor TLR1:TLR2 Cascade (Sus scrofa)
        
        MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Sus scrofa)
        
        MAP kinase activation (Sus scrofa)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Sus scrofa)
        
        ERK/MAPK targets (Sus scrofa)
        
        ERKs are inactivated (Sus scrofa)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Sus scrofa)
        
        ERK-specific DUSP [nucleoplasm] (Sus scrofa)
        
        DUSP7 [nucleoplasm] (Sus scrofa)
      - Toll Like Receptor TLR6:TLR2 Cascade (Sus scrofa)
        
        MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Sus scrofa)
        
        MAP kinase activation (Sus scrofa)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Sus scrofa)
        
        ERK/MAPK targets (Sus scrofa)
        
        ERKs are inactivated (Sus scrofa)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Sus scrofa)
        
        ERK-specific DUSP [nucleoplasm] (Sus scrofa)
        
        DUSP7 [nucleoplasm] (Sus scrofa)
    - Toll Like Receptor 3 (TLR3) Cascade (Sus scrofa)
      - MAP kinase activation (Sus scrofa)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Sus scrofa)
        
        ERK/MAPK targets (Sus scrofa)
        
        ERKs are inactivated (Sus scrofa)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Sus scrofa)
        
        ERK-specific DUSP [nucleoplasm] (Sus scrofa)
        
        DUSP7 [nucleoplasm] (Sus scrofa)
    - Toll Like Receptor 4 (TLR4) Cascade (Sus scrofa)
      - MyD88-independent TLR4 cascade (Sus scrofa)
        
        TRIF (TICAM1)-mediated TLR4 signaling (Sus scrofa)
        
        MAP kinase activation (Sus scrofa)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Sus scrofa)
        
        ERK/MAPK targets (Sus scrofa)
        
        ERKs are inactivated (Sus scrofa)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Sus scrofa)
        
        ERK-specific DUSP [nucleoplasm] (Sus scrofa)
        
        DUSP7 [nucleoplasm] (Sus scrofa)
      - MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Sus scrofa)
        
        MAP kinase activation (Sus scrofa)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Sus scrofa)
        
        ERK/MAPK targets (Sus scrofa)
        
        ERKs are inactivated (Sus scrofa)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Sus scrofa)
        
        ERK-specific DUSP [nucleoplasm] (Sus scrofa)
        
        DUSP7 [nucleoplasm] (Sus scrofa)
    - Toll Like Receptor 5 (TLR5) Cascade (Sus scrofa)
      - MyD88 cascade initiated on plasma membrane (Sus scrofa)
        
        MAP kinase activation (Sus scrofa)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Sus scrofa)
        
        ERK/MAPK targets (Sus scrofa)
        
        ERKs are inactivated (Sus scrofa)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Sus scrofa)
        
        ERK-specific DUSP [nucleoplasm] (Sus scrofa)
        
        DUSP7 [nucleoplasm] (Sus scrofa)
    - Toll Like Receptor 7/8 (TLR7/8) Cascade (Sus scrofa)
      - MyD88 dependent cascade initiated on endosome (Sus scrofa)
        
        TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Sus scrofa)
        
        MAP kinase activation (Sus scrofa)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Sus scrofa)
        
        ERK/MAPK targets (Sus scrofa)
        
        ERKs are inactivated (Sus scrofa)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Sus scrofa)
        
        ERK-specific DUSP [nucleoplasm] (Sus scrofa)
        
        DUSP7 [nucleoplasm] (Sus scrofa)
    - Toll Like Receptor 9 (TLR9) Cascade (Sus scrofa)
      - MyD88 dependent cascade initiated on endosome (Sus scrofa)
        
        TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Sus scrofa)
        
        MAP kinase activation (Sus scrofa)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Sus scrofa)
        
        ERK/MAPK targets (Sus scrofa)
        
        ERKs are inactivated (Sus scrofa)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Sus scrofa)
        
        ERK-specific DUSP [nucleoplasm] (Sus scrofa)
        
        DUSP7 [nucleoplasm] (Sus scrofa)

Signal Transduction (Sus scrofa)

- Signaling by Receptor Tyrosine Kinases (Sus scrofa)
  - Signaling by NTRKs (Sus scrofa)
    - Signaling by NTRK1 (TRKA) (Sus scrofa)
      - Nuclear Events (kinase and transcription factor activation) (Sus scrofa)
        
        ERK/MAPK targets (Sus scrofa)
        
        ERKs are inactivated (Sus scrofa)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Sus scrofa)
        
        ERK-specific DUSP [nucleoplasm] (Sus scrofa)
        
        DUSP7 [nucleoplasm] (Sus scrofa)

External Reference Information

External Reference

UniProt:F1SIY1

Gene Names

DUSP7

Reference Genes

ENSEMBL:ENSSSCG00000059013.1

Other Identifiers

100521473

GO:0003824

GO:0004721

GO:0004722

GO:0004725

GO:0005814

GO:0005815

GO:0005829

GO:0005856

GO:0005929

GO:0006470

GO:0008138

GO:0016311

GO:0016787

GO:0016791

GO:0017017

GO:0017018

GO:0036064

GO:0036211

GO:0043226

GO:0044782

GO:0060271

GO:0140096

Ssc.27211.1.S1_at

Participates

as a member of

ERK-specific DUSP [nucleoplasm] (Sus scrofa)

Other forms of this molecule

DUSP7 [cytosol]

Inferred From

DUSP7 [nucleoplasm] (Homo sapiens)

Cross References

OpenTargets

ENSG00000164086

Ensembl

ENSSSCP00000012182, ENSSSCG00000059013, ENSSSCT00000012510

VGNC

91615

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