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ROCK1 [cytosol]
Stable Identifier
R-SSC-212509
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
cytosol
Synonyms
A0A5G2QIS7
Locations in the PathwayBrowser
Expand all
Developmental Biology (Sus scrofa)
Nervous system development (Sus scrofa)
Axon guidance (Sus scrofa)
EPH-Ephrin signaling (Sus scrofa)
EPHB-mediated forward signaling (Sus scrofa)
RHOA:GTP binds ROCK, activating it (Sus scrofa)
RHOA:GTP:ROCK1,ROCK2 [plasma membrane] (Sus scrofa)
ROCK1,ROCK2 [cytosol] (Sus scrofa)
ROCK1 [cytosol] (Sus scrofa)
ROCK1,ROCK2 [cytosol] (Sus scrofa)
ROCK1 [cytosol] (Sus scrofa)
Semaphorin interactions (Sus scrofa)
Sema4D in semaphorin signaling (Sus scrofa)
Sema4D induced cell migration and growth-cone collapse (Sus scrofa)
ROCK activation by RHO (Sus scrofa)
Activated ROCK:RhoA/B/C:GTP [plasma membrane] (Sus scrofa)
ROCK1,ROCK2 [cytosol] (Sus scrofa)
ROCK1 [cytosol] (Sus scrofa)
ROCK1,ROCK2 [cytosol] (Sus scrofa)
ROCK1 [cytosol] (Sus scrofa)
ROCK1,ROCK2:ROCKi [cytosol] (Sus scrofa)
ROCK1,ROCK2 [cytosol] (Sus scrofa)
ROCK1 [cytosol] (Sus scrofa)
ROCK1,2 bind ROCKi (Sus scrofa)
ROCK1,ROCK2 [cytosol] (Sus scrofa)
ROCK1 [cytosol] (Sus scrofa)
ROCK1,ROCK2:ROCKi [cytosol] (Sus scrofa)
ROCK1,ROCK2 [cytosol] (Sus scrofa)
ROCK1 [cytosol] (Sus scrofa)
Programmed Cell Death (Sus scrofa)
Apoptosis (Sus scrofa)
Apoptotic execution phase (Sus scrofa)
Apoptotic cleavage of cellular proteins (Sus scrofa)
Caspase-mediated cleavage of Rock-1 (Sus scrofa)
ROCK1 [cytosol] (Sus scrofa)
Signal Transduction (Sus scrofa)
Signaling by GPCR (Sus scrofa)
GPCR downstream signalling (Sus scrofa)
G alpha (12/13) signalling events (Sus scrofa)
ROCK activation by RHO (Sus scrofa)
Activated ROCK:RhoA/B/C:GTP [plasma membrane] (Sus scrofa)
ROCK1,ROCK2 [cytosol] (Sus scrofa)
ROCK1 [cytosol] (Sus scrofa)
ROCK1,ROCK2 [cytosol] (Sus scrofa)
ROCK1 [cytosol] (Sus scrofa)
ROCK1,ROCK2:ROCKi [cytosol] (Sus scrofa)
ROCK1,ROCK2 [cytosol] (Sus scrofa)
ROCK1 [cytosol] (Sus scrofa)
ROCK1,2 bind ROCKi (Sus scrofa)
ROCK1,ROCK2 [cytosol] (Sus scrofa)
ROCK1 [cytosol] (Sus scrofa)
ROCK1,ROCK2:ROCKi [cytosol] (Sus scrofa)
ROCK1,ROCK2 [cytosol] (Sus scrofa)
ROCK1 [cytosol] (Sus scrofa)
Signaling by Receptor Tyrosine Kinases (Sus scrofa)
Signaling by VEGF (Sus scrofa)
VEGFA-VEGFR2 Pathway (Sus scrofa)
Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 (Sus scrofa)
RHOA:GTP:Mg2+:Activated ROCK1,ROCK2 [cytosol] (Sus scrofa)
ROCK1,ROCK2 [cytosol] (Sus scrofa)
ROCK1 [cytosol] (Sus scrofa)
RHOA:GTP:Mg2+ binds ROCK1,ROCK2 (Sus scrofa)
RHOA:GTP:ROCK1,ROCK2 [plasma membrane] (Sus scrofa)
ROCK1,ROCK2 [cytosol] (Sus scrofa)
ROCK1 [cytosol] (Sus scrofa)
ROCK1,ROCK2 [cytosol] (Sus scrofa)
ROCK1 [cytosol] (Sus scrofa)
ROCK1,ROCK2 are activated (Sus scrofa)
RHOA:GTP:Mg2+:Activated ROCK1,ROCK2 [cytosol] (Sus scrofa)
ROCK1,ROCK2 [cytosol] (Sus scrofa)
ROCK1 [cytosol] (Sus scrofa)
RHOA:GTP:ROCK1,ROCK2 [plasma membrane] (Sus scrofa)
ROCK1,ROCK2 [cytosol] (Sus scrofa)
ROCK1 [cytosol] (Sus scrofa)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Sus scrofa)
Signaling by Rho GTPases (Sus scrofa)
RHO GTPase Effectors (Sus scrofa)
RHO GTPases Activate ROCKs (Sus scrofa)
ROCK activation by RHO (Sus scrofa)
Activated ROCK:RhoA/B/C:GTP [plasma membrane] (Sus scrofa)
ROCK1,ROCK2 [cytosol] (Sus scrofa)
ROCK1 [cytosol] (Sus scrofa)
ROCK1,ROCK2 [cytosol] (Sus scrofa)
ROCK1 [cytosol] (Sus scrofa)
ROCK1,ROCK2:ROCKi [cytosol] (Sus scrofa)
ROCK1,ROCK2 [cytosol] (Sus scrofa)
ROCK1 [cytosol] (Sus scrofa)
ROCK1,2 bind ROCKi (Sus scrofa)
ROCK1,ROCK2 [cytosol] (Sus scrofa)
ROCK1 [cytosol] (Sus scrofa)
ROCK1,ROCK2:ROCKi [cytosol] (Sus scrofa)
ROCK1,ROCK2 [cytosol] (Sus scrofa)
ROCK1 [cytosol] (Sus scrofa)
RHO GTPase cycle (Sus scrofa)
RHOA GTPase cycle (Sus scrofa)
RHOA binds effectors at the plasma membrane (Sus scrofa)
RHOA plasma membrane effectors [cytosol] (Sus scrofa)
ROCK1 [cytosol] (Sus scrofa)
RHOA:GTP:cytosolic RHOA effectors [plasma membrane] (Sus scrofa)
RHOA plasma membrane effectors [cytosol] (Sus scrofa)
ROCK1 [cytosol] (Sus scrofa)
RHOB GTPase cycle (Sus scrofa)
RHOB binds effectors at the plasma membrane (Sus scrofa)
RHOB effectors (plasma membrane) [cytosol] (Sus scrofa)
ROCK1 [cytosol] (Sus scrofa)
RHOB:GTP:cytosolic RHOB effectors [plasma membrane] (Sus scrofa)
RHOB effectors (plasma membrane) [cytosol] (Sus scrofa)
ROCK1 [cytosol] (Sus scrofa)
RHOBTB GTPase Cycle (Sus scrofa)
RHOBTB1 GTPase cycle (Sus scrofa)
RHOBTB1 binds interacting proteins at the endosome membrane (Sus scrofa)
RHOBTB1 interacting proteins [cytosol] (Sus scrofa)
ROCK1 [cytosol] (Sus scrofa)
RHOBTB1:GTP:RHOBTB1 interacting proteins [endosome membrane] (Sus scrofa)
RHOBTB1 interacting proteins [cytosol] (Sus scrofa)
ROCK1 [cytosol] (Sus scrofa)
RHOC GTPase cycle (Sus scrofa)
RHOC binds effectors at the plasma membrane (Sus scrofa)
RHOC effectors [cytosol] (Sus scrofa)
ROCK1 [cytosol] (Sus scrofa)
RHOC:GTP:RHOC effectors [plasma membrane] (Sus scrofa)
RHOC effectors [cytosol] (Sus scrofa)
ROCK1 [cytosol] (Sus scrofa)
RHOH GTPase cycle (Sus scrofa)
RHOH binds effectors at the plasma membrane (Sus scrofa)
RHOH effectors [cytosol] (Sus scrofa)
ROCK1 [cytosol] (Sus scrofa)
RHOH:GTP:RHOH effectors [plasma membrane] (Sus scrofa)
RHOH effectors [cytosol] (Sus scrofa)
ROCK1 [cytosol] (Sus scrofa)
RND3 GTPase cycle (Sus scrofa)
RND3 binds effectors (Sus scrofa)
RND3 effectors [cytosol] (Sus scrofa)
ROCK1 [cytosol] (Sus scrofa)
RND3:GTP:RND3 effectors [plasma membrane] (Sus scrofa)
RND3 effectors [cytosol] (Sus scrofa)
ROCK1 [cytosol] (Sus scrofa)
External Reference Information
External Reference
UniProt:A0A5G2QIS7
Reference Genes
ENSEMBL:ENSSSCG00000021893.4
Other Identifiers
397447
GO:0000166
GO:0003824
GO:0004672
GO:0004674
GO:0005524
GO:0005856
GO:0005886
GO:0007010
GO:0007165
GO:0007266
GO:0016020
GO:0016301
GO:0016310
GO:0016740
GO:0023052
GO:0030036
GO:0031267
GO:0043226
GO:0046872
GO:0140096
Ssc.16167.1.A1_at
Ssc.24477.1.A1_at
Participates
as a member of
RHOA plasma membrane effectors [cytosol] (Sus scrofa)
RND3 effectors [cytosol] (Sus scrofa)
RHOC effectors [cytosol] (Sus scrofa)
RHOBTB1 interacting proteins [cytosol] (Sus scrofa)
RHOB effectors (plasma membrane) [cytosol] (Sus scrofa)
ROCK1,ROCK2 [cytosol] (Sus scrofa)
as a candidate of
RHOH effectors [cytosol] (Sus scrofa)
as an input of
Caspase-mediated cleavage of Rock-1 (Sus scrofa)
Other forms of this molecule
ROCK1 [extracellular region]
ROCK1 [secretory granule lumen]
ROCK1(1114-1354) [cytosol]
ROCK1(1-1113) [cytosol]
Inferred From
Activated ROCK1 [cytosol]
(Homo sapiens)
ROCK1 [cytosol]
(Homo sapiens)
Cross References
Ensembl
ENSSSCT00000069047
,
ENSSSCG00000021893
,
ENSSSCP00000063816
VGNC
98294
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