Reactome | TLN1 [cytosol]

TLN1 [cytosol]

Stable Identifier

R-SSC-350713

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

cytosol

Synonyms

A0A287AC34

Locations in the PathwayBrowser

Expand all

Immune System (Sus scrofa)

- Cytokine Signaling in Immune system (Sus scrofa)
  - FLT3 Signaling (Sus scrofa)
    - RAF/MAP kinase cascade (Sus scrofa)
      - MAP2K and MAPK activation (Sus scrofa)
        
        Dissociation of RAS:RAF complex (Sus scrofa)
        
        RAF/MAPK scaffolds [cytosol] (Sus scrofa)
        
        Focal Adhesion/Focal contacts [plasma membrane] (Sus scrofa)
        
        Vinculin bound to alphaIIbbeta3 [plasma membrane] (Sus scrofa)
        
        Focal complex [plasma membrane] (Sus scrofa)
        
        Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        TLN1 [cytosol] (Sus scrofa)
        
        activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Sus scrofa)
        
        RAF/MAPK scaffolds [cytosol] (Sus scrofa)
        
        Focal Adhesion/Focal contacts [plasma membrane] (Sus scrofa)
        
        Vinculin bound to alphaIIbbeta3 [plasma membrane] (Sus scrofa)
        
        Focal complex [plasma membrane] (Sus scrofa)
        
        Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        TLN1 [cytosol] (Sus scrofa)
        
        MAP2Ks and MAPKs bind to the activated RAF complex (Sus scrofa)
        
        RAF/MAPK scaffolds [cytosol] (Sus scrofa)
        
        Focal Adhesion/Focal contacts [plasma membrane] (Sus scrofa)
        
        Vinculin bound to alphaIIbbeta3 [plasma membrane] (Sus scrofa)
        
        Focal complex [plasma membrane] (Sus scrofa)
        
        Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        TLN1 [cytosol] (Sus scrofa)
        
        activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
        
        RAF/MAPK scaffolds [cytosol] (Sus scrofa)
        
        Focal Adhesion/Focal contacts [plasma membrane] (Sus scrofa)
        
        Vinculin bound to alphaIIbbeta3 [plasma membrane] (Sus scrofa)
        
        Focal complex [plasma membrane] (Sus scrofa)
        
        Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        TLN1 [cytosol] (Sus scrofa)
        
        MAP2Ks phosphorylate MAPKs (Sus scrofa)
        
        activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Sus scrofa)
        
        activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
        
        RAF/MAPK scaffolds [cytosol] (Sus scrofa)
        
        Focal Adhesion/Focal contacts [plasma membrane] (Sus scrofa)
        
        Vinculin bound to alphaIIbbeta3 [plasma membrane] (Sus scrofa)
        
        Focal complex [plasma membrane] (Sus scrofa)
        
        Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        TLN1 [cytosol] (Sus scrofa)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Sus scrofa)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
        
        RAF/MAPK scaffolds [cytosol] (Sus scrofa)
        
        Focal Adhesion/Focal contacts [plasma membrane] (Sus scrofa)
        
        Vinculin bound to alphaIIbbeta3 [plasma membrane] (Sus scrofa)
        
        Focal complex [plasma membrane] (Sus scrofa)
        
        Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        TLN1 [cytosol] (Sus scrofa)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
        
        RAF/MAPK scaffolds [cytosol] (Sus scrofa)
        
        Focal Adhesion/Focal contacts [plasma membrane] (Sus scrofa)
        
        Vinculin bound to alphaIIbbeta3 [plasma membrane] (Sus scrofa)
        
        Focal complex [plasma membrane] (Sus scrofa)
        
        Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        TLN1 [cytosol] (Sus scrofa)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Sus scrofa)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
        
        RAF/MAPK scaffolds [cytosol] (Sus scrofa)
        
        Focal Adhesion/Focal contacts [plasma membrane] (Sus scrofa)
        
        Vinculin bound to alphaIIbbeta3 [plasma membrane] (Sus scrofa)
        
        Focal complex [plasma membrane] (Sus scrofa)
        
        Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        TLN1 [cytosol] (Sus scrofa)
        
        activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Sus scrofa)
        
        RAF/MAPK scaffolds [cytosol] (Sus scrofa)
        
        Focal Adhesion/Focal contacts [plasma membrane] (Sus scrofa)
        
        Vinculin bound to alphaIIbbeta3 [plasma membrane] (Sus scrofa)
        
        Focal complex [plasma membrane] (Sus scrofa)
        
        Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        TLN1 [cytosol] (Sus scrofa)
        
        RAF phosphorylates MAP2K dimer (Sus scrofa)
        
        activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
        
        RAF/MAPK scaffolds [cytosol] (Sus scrofa)
        
        Focal Adhesion/Focal contacts [plasma membrane] (Sus scrofa)
        
        Vinculin bound to alphaIIbbeta3 [plasma membrane] (Sus scrofa)
        
        Focal complex [plasma membrane] (Sus scrofa)
        
        Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        TLN1 [cytosol] (Sus scrofa)
        
        activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Sus scrofa)
        
        activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
        
        RAF/MAPK scaffolds [cytosol] (Sus scrofa)
        
        Focal Adhesion/Focal contacts [plasma membrane] (Sus scrofa)
        
        Vinculin bound to alphaIIbbeta3 [plasma membrane] (Sus scrofa)
        
        Focal complex [plasma membrane] (Sus scrofa)
        
        Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        TLN1 [cytosol] (Sus scrofa)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
        
        RAF/MAPK scaffolds [cytosol] (Sus scrofa)
        
        Focal Adhesion/Focal contacts [plasma membrane] (Sus scrofa)
        
        Vinculin bound to alphaIIbbeta3 [plasma membrane] (Sus scrofa)
        
        Focal complex [plasma membrane] (Sus scrofa)
        
        Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        TLN1 [cytosol] (Sus scrofa)

Muscle contraction (Sus scrofa)

- Smooth Muscle Contraction (Sus scrofa)
  - Calcium Binds Caldesmon (Sus scrofa)
    - Calcium Bound Myosin Actin Complex [plasma membrane] (Sus scrofa)
      - integrin:cytoskeletal ahesion complex [plasma membrane] (Sus scrofa)
        
        TLN1 [cytosol] (Sus scrofa)
    - Inactive Myosin Actin Contractile Complex [plasma membrane] (Sus scrofa)
      - integrin:cytoskeletal ahesion complex [plasma membrane] (Sus scrofa)
        
        TLN1 [cytosol] (Sus scrofa)
  - Myosin Binds ATP (Sus scrofa)
    - ATP:Calcium Bound Myosin Actin Complex [plasma membrane] (Sus scrofa)
      - integrin:cytoskeletal ahesion complex [plasma membrane] (Sus scrofa)
        
        TLN1 [cytosol] (Sus scrofa)
    - Calcium Bound Myosin Actin Complex [plasma membrane] (Sus scrofa)
      - integrin:cytoskeletal ahesion complex [plasma membrane] (Sus scrofa)
        
        TLN1 [cytosol] (Sus scrofa)
  - Release Of ADP From Myosin (Sus scrofa)
    - ADP:Calcium Bound Myosin Actin Complex [plasma membrane] (Sus scrofa)
      - integrin:cytoskeletal ahesion complex [plasma membrane] (Sus scrofa)
        
        TLN1 [cytosol] (Sus scrofa)
    - Calcium Bound Myosin Actin Complex [plasma membrane] (Sus scrofa)
      - integrin:cytoskeletal ahesion complex [plasma membrane] (Sus scrofa)
        
        TLN1 [cytosol] (Sus scrofa)

Signal Transduction (Sus scrofa)

- Integrin signaling (Sus scrofa)
  - Activated integrin alphaIIb beta3 binds SHC1 (Sus scrofa)
    - Integrin alphaIIb beta 3:p(Y530)-SRC:CSK:Talin:RIAM complex:SHC [plasma membrane] (Sus scrofa)
      - Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        TLN1 [cytosol] (Sus scrofa)
    - Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Sus scrofa)
      - Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        TLN1 [cytosol] (Sus scrofa)
  - Activation of Talin (Sus scrofa)
    - TLN1 [cytosol] (Sus scrofa)
    - Talin:RIAM complex [plasma membrane] (Sus scrofa)
      - TLN1 [cytosol] (Sus scrofa)
  - Integrin alphaIIb beta3 activation (Sus scrofa)
    - Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Sus scrofa)
      - Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        TLN1 [cytosol] (Sus scrofa)
    - Talin:RIAM complex [plasma membrane] (Sus scrofa)
      - TLN1 [cytosol] (Sus scrofa)
  - SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow (Sus scrofa)
    - Integrin alpha IIb beta 3:p-Y530-SRC:CSK:Talin:RIAM complex:p-Y427-SHC [plasma membrane] (Sus scrofa)
      - Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        TLN1 [cytosol] (Sus scrofa)
    - Integrin alphaIIb beta 3:p(Y530)-SRC:CSK:Talin:RIAM complex:SHC [plasma membrane] (Sus scrofa)
      - Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        TLN1 [cytosol] (Sus scrofa)
  - SHC1 dissociates from integrin alphaIIb beta3 (Sus scrofa)
    - Integrin alpha IIb beta 3:p-Y530-SRC:CSK:Talin:RIAM complex:p-Y427-SHC [plasma membrane] (Sus scrofa)
      - Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        TLN1 [cytosol] (Sus scrofa)
    - Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Sus scrofa)
      - Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        TLN1 [cytosol] (Sus scrofa)
- MAPK family signaling cascades (Sus scrofa)
  - MAPK1/MAPK3 signaling (Sus scrofa)
    - RAF/MAP kinase cascade (Sus scrofa)
      - MAP2K and MAPK activation (Sus scrofa)
        
        Dissociation of RAS:RAF complex (Sus scrofa)
        
        RAF/MAPK scaffolds [cytosol] (Sus scrofa)
        
        Focal Adhesion/Focal contacts [plasma membrane] (Sus scrofa)
        
        Vinculin bound to alphaIIbbeta3 [plasma membrane] (Sus scrofa)
        
        Focal complex [plasma membrane] (Sus scrofa)
        
        Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        TLN1 [cytosol] (Sus scrofa)
        
        activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Sus scrofa)
        
        RAF/MAPK scaffolds [cytosol] (Sus scrofa)
        
        Focal Adhesion/Focal contacts [plasma membrane] (Sus scrofa)
        
        Vinculin bound to alphaIIbbeta3 [plasma membrane] (Sus scrofa)
        
        Focal complex [plasma membrane] (Sus scrofa)
        
        Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        TLN1 [cytosol] (Sus scrofa)
        
        MAP2Ks and MAPKs bind to the activated RAF complex (Sus scrofa)
        
        RAF/MAPK scaffolds [cytosol] (Sus scrofa)
        
        Focal Adhesion/Focal contacts [plasma membrane] (Sus scrofa)
        
        Vinculin bound to alphaIIbbeta3 [plasma membrane] (Sus scrofa)
        
        Focal complex [plasma membrane] (Sus scrofa)
        
        Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        TLN1 [cytosol] (Sus scrofa)
        
        activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
        
        RAF/MAPK scaffolds [cytosol] (Sus scrofa)
        
        Focal Adhesion/Focal contacts [plasma membrane] (Sus scrofa)
        
        Vinculin bound to alphaIIbbeta3 [plasma membrane] (Sus scrofa)
        
        Focal complex [plasma membrane] (Sus scrofa)
        
        Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        TLN1 [cytosol] (Sus scrofa)
        
        MAP2Ks phosphorylate MAPKs (Sus scrofa)
        
        activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Sus scrofa)
        
        activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
        
        RAF/MAPK scaffolds [cytosol] (Sus scrofa)
        
        Focal Adhesion/Focal contacts [plasma membrane] (Sus scrofa)
        
        Vinculin bound to alphaIIbbeta3 [plasma membrane] (Sus scrofa)
        
        Focal complex [plasma membrane] (Sus scrofa)
        
        Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        TLN1 [cytosol] (Sus scrofa)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Sus scrofa)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
        
        RAF/MAPK scaffolds [cytosol] (Sus scrofa)
        
        Focal Adhesion/Focal contacts [plasma membrane] (Sus scrofa)
        
        Vinculin bound to alphaIIbbeta3 [plasma membrane] (Sus scrofa)
        
        Focal complex [plasma membrane] (Sus scrofa)
        
        Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        TLN1 [cytosol] (Sus scrofa)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
        
        RAF/MAPK scaffolds [cytosol] (Sus scrofa)
        
        Focal Adhesion/Focal contacts [plasma membrane] (Sus scrofa)
        
        Vinculin bound to alphaIIbbeta3 [plasma membrane] (Sus scrofa)
        
        Focal complex [plasma membrane] (Sus scrofa)
        
        Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        TLN1 [cytosol] (Sus scrofa)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Sus scrofa)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
        
        RAF/MAPK scaffolds [cytosol] (Sus scrofa)
        
        Focal Adhesion/Focal contacts [plasma membrane] (Sus scrofa)
        
        Vinculin bound to alphaIIbbeta3 [plasma membrane] (Sus scrofa)
        
        Focal complex [plasma membrane] (Sus scrofa)
        
        Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        TLN1 [cytosol] (Sus scrofa)
        
        activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Sus scrofa)
        
        RAF/MAPK scaffolds [cytosol] (Sus scrofa)
        
        Focal Adhesion/Focal contacts [plasma membrane] (Sus scrofa)
        
        Vinculin bound to alphaIIbbeta3 [plasma membrane] (Sus scrofa)
        
        Focal complex [plasma membrane] (Sus scrofa)
        
        Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        TLN1 [cytosol] (Sus scrofa)
        
        RAF phosphorylates MAP2K dimer (Sus scrofa)
        
        activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
        
        RAF/MAPK scaffolds [cytosol] (Sus scrofa)
        
        Focal Adhesion/Focal contacts [plasma membrane] (Sus scrofa)
        
        Vinculin bound to alphaIIbbeta3 [plasma membrane] (Sus scrofa)
        
        Focal complex [plasma membrane] (Sus scrofa)
        
        Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        TLN1 [cytosol] (Sus scrofa)
        
        activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Sus scrofa)
        
        activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
        
        RAF/MAPK scaffolds [cytosol] (Sus scrofa)
        
        Focal Adhesion/Focal contacts [plasma membrane] (Sus scrofa)
        
        Vinculin bound to alphaIIbbeta3 [plasma membrane] (Sus scrofa)
        
        Focal complex [plasma membrane] (Sus scrofa)
        
        Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        TLN1 [cytosol] (Sus scrofa)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
        
        RAF/MAPK scaffolds [cytosol] (Sus scrofa)
        
        Focal Adhesion/Focal contacts [plasma membrane] (Sus scrofa)
        
        Vinculin bound to alphaIIbbeta3 [plasma membrane] (Sus scrofa)
        
        Focal complex [plasma membrane] (Sus scrofa)
        
        Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        Talin:RIAM complex [plasma membrane] (Sus scrofa)
        
        TLN1 [cytosol] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A287AC34

Reference Genes

ENSEMBL:ENSSSCG00000005317

Other Identifiers

100157220

AEMK02000005

ENSSSCG00000005317

ENSSSCP00000041366

ENSSSCT00000062014

EntrezGene:100157220

EntrezGene:TLN1

GO:0001726

GO:0001786

GO:0003674

GO:0003779

GO:0005178

GO:0005198

GO:0005200

GO:0005575

GO:0005622

GO:0005623

GO:0005856

GO:0005912

GO:0005925

GO:0007010

GO:0007016

GO:0007044

GO:0007155

GO:0007165

GO:0007229

GO:0008092

GO:0008150

GO:0008289

GO:0017166

GO:0022607

GO:0030274

GO:0030866

GO:0033622

GO:0034330

GO:0035091

GO:0043167

GO:0043226

GO:0051015

GO:0065003

HGNC:11845

IPR000299

IPR002558

IPR011993

IPR014352

IPR015009

IPR015224

IPR018979

IPR019747

IPR019748

IPR019749

IPR029071

IPR032425

IPR035963

IPR035964

IPR036476

IPR036723

IPR037438

PF00373

PF01608

PF08913

PF09141

PF09379

PF16511

SM00295

SM00307

SM01244

Ssc.16858.1.S1_at

Ssc.25160.1.S1_at

TLN1

TLN1-201

UPI000A2B4D24

XM_021065652

XM_021065656

XM_021065662

XM_021065668

XM_021065677

XM_021065688

XM_021065699

XP_020921311

XP_020921315

XP_020921321

XP_020921327

XP_020921336

XP_020921347

XP_020921358

Participant Of

hasComponent

input

Activation of Talin

hasMember

Platelet releasate cytosolic proteins [cytosol]

output

Inhibition of integrin activation by sequestering PIP5KIgamma

Other forms of this molecule

TLN1 [extracellular region]

Inferred From

TLN1 [cytosol] (Homo sapiens)

Cross References

Target Pathogen

5b354852be737e166372eb76

Ensembl

ENSSSCP00000041366, ENSSSCG00000005317, ENSSSCT00000062014