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SPDL1 [cytosol]
Stable Identifier
R-SSC-377733
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
cytosol
Synonyms
SPDL1, I3LS43
Locations in the PathwayBrowser
Expand all
Cell Cycle (Sus scrofa)
Cell Cycle Checkpoints (Sus scrofa)
Mitotic Spindle Checkpoint (Sus scrofa)
Amplification of signal from the kinetochores (Sus scrofa)
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal (Sus scrofa)
MAD2 associates with the Mad1 kinetochore complex (Sus scrofa)
Kinetochore:Mad1:MAD2 Complex [cytosol] (Sus scrofa)
Mad1:kinetochore complex [cytosol] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
SPDL1 [cytosol] (Sus scrofa)
Mad1:kinetochore complex [cytosol] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
SPDL1 [cytosol] (Sus scrofa)
MAD2 converted to an inhibitory state via interaction with Mad1 (Sus scrofa)
Kinetochore:Mad1:MAD2 Complex [cytosol] (Sus scrofa)
Mad1:kinetochore complex [cytosol] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
SPDL1 [cytosol] (Sus scrofa)
Mad1 binds kinetochore (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
SPDL1 [cytosol] (Sus scrofa)
Mad1:kinetochore complex [cytosol] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
SPDL1 [cytosol] (Sus scrofa)
Release of activated MAD2 from kinetochores (Sus scrofa)
Kinetochore:Mad1:MAD2 Complex [cytosol] (Sus scrofa)
Mad1:kinetochore complex [cytosol] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
SPDL1 [cytosol] (Sus scrofa)
Mad1:kinetochore complex [cytosol] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
SPDL1 [cytosol] (Sus scrofa)
Cell Cycle, Mitotic (Sus scrofa)
M Phase (Sus scrofa)
Mitotic Metaphase and Anaphase (Sus scrofa)
Mitotic Anaphase (Sus scrofa)
Separation of Sister Chromatids (Sus scrofa)
ESPL1 (Separase) cleaves centromeric cohesin (Sus scrofa)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
SPDL1 [cytosol] (Sus scrofa)
p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Sus scrofa)
Microtubule-bound kinetochore [cytosol] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
SPDL1 [cytosol] (Sus scrofa)
Separation of sister chromatids (Sus scrofa)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
SPDL1 [cytosol] (Sus scrofa)
Sister Centromere:Kinetochore:Microtubules [cytosol] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
SPDL1 [cytosol] (Sus scrofa)
Mitotic Prometaphase (Sus scrofa)
EML4 and NUDC in mitotic spindle formation (Sus scrofa)
EML4 recruits NUDC to mitotic spindle (Sus scrofa)
Microtubule-bound kinetochore [cytosol] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
SPDL1 [cytosol] (Sus scrofa)
p-S274,S326-NUDC:EML4 homotrimer:Microtubule-bound kinetochore [spindle] (Sus scrofa)
Microtubule-bound kinetochore [cytosol] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
SPDL1 [cytosol] (Sus scrofa)
Kinetochore capture of astral microtubules (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
SPDL1 [cytosol] (Sus scrofa)
Microtubule-bound kinetochore [cytosol] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
SPDL1 [cytosol] (Sus scrofa)
Resolution of Sister Chromatid Cohesion (Sus scrofa)
CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Sus scrofa)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Sus scrofa)
Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Sus scrofa)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
SPDL1 [cytosol] (Sus scrofa)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
SPDL1 [cytosol] (Sus scrofa)
Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Sus scrofa)
Microtubule-bound kinetochore [cytosol] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
SPDL1 [cytosol] (Sus scrofa)
Kinetochore assembly (Sus scrofa)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Sus scrofa)
Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Sus scrofa)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
SPDL1 [cytosol] (Sus scrofa)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
SPDL1 [cytosol] (Sus scrofa)
Microtubule-bound kinetochore [cytosol] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
SPDL1 [cytosol] (Sus scrofa)
PP2A-B56 dephosphorylates centromeric cohesin (Sus scrofa)
p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Sus scrofa)
Microtubule-bound kinetochore [cytosol] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
SPDL1 [cytosol] (Sus scrofa)
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Sus scrofa)
Microtubule-bound kinetochore [cytosol] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
SPDL1 [cytosol] (Sus scrofa)
Phosphorylation of cohesin by PLK1 at centromeres (Sus scrofa)
Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Sus scrofa)
Microtubule-bound kinetochore [cytosol] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
SPDL1 [cytosol] (Sus scrofa)
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Sus scrofa)
Microtubule-bound kinetochore [cytosol] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
SPDL1 [cytosol] (Sus scrofa)
Signal Transduction (Sus scrofa)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Sus scrofa)
Signaling by Rho GTPases (Sus scrofa)
RHO GTPase Effectors (Sus scrofa)
RHO GTPases Activate Formins (Sus scrofa)
AURKB phosphorylates DIAPH2-2 at kinetochores (Sus scrofa)
Kinetochore:CDC42:GTP:DIAPH2-2 [cytosol] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
SPDL1 [cytosol] (Sus scrofa)
Kinetochore:CDC42:GTP:p-S196-DIAPH2-2 [cytosol] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
SPDL1 [cytosol] (Sus scrofa)
CDC42:GTP recruits DIAPH2-2 to kinetochores (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
SPDL1 [cytosol] (Sus scrofa)
Kinetochore:CDC42:GTP:DIAPH2-2 [cytosol] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
SPDL1 [cytosol] (Sus scrofa)
Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
SPDL1 [cytosol] (Sus scrofa)
Kinetochore:CDC42:GTP:p-S196-DIAPH2-2 [cytosol] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
SPDL1 [cytosol] (Sus scrofa)
Microtubule-bound kinetochore [cytosol] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
SPDL1 [cytosol] (Sus scrofa)
External Reference Information
External Reference
UniProt:I3LS43
Gene Names
SPDL1
Reference Genes
BioGPS Gene:100510938 SPDL1
ENSEMBL:ENSSSCG00000025965.4
ENSEMBL:ENSSSCG00005025830.1 SPDL1
KEGG Gene (Sus scrofa):100510938 SPDL1
Monarch:100510938 SPDL1
NCBI Gene:100510938 SPDL1
Reference Transcript
RefSeq:XM_005672552.2 SPDL1
RefSeq:XM_003134063.4 SPDL1
Other Identifiers
100510938
GO:0000132
GO:0000278
GO:0000775
GO:0000776
GO:0000922
GO:0000940
GO:0005634
GO:0005694
GO:0005737
GO:0005813
GO:0005815
GO:0005856
GO:0007010
GO:0007049
GO:0007059
GO:0007080
GO:0007094
GO:0007163
GO:0016477
GO:0019899
GO:0023052
GO:0034501
GO:0043226
GO:0043515
GO:0048870
GO:0051301
GO:0140014
Ssc.22545.1.A1_at
Participates
as a component of
Kinetochore [cytosol] (Sus scrofa)
Inferred From
SPDL1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_003134111.2
,
XP_005672609.1
OpenTargets
ENSG00000040275
Ensembl
ENSSSCG00000025965
,
ENSSSCP00000026934
,
ENSSSCT00000027418
VGNC
93395
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