Reactome | SFI1 [cytosol]

SFI1 [cytosol]

Stable Identifier

R-SSC-380265

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

cytosol

Synonyms

SFI1, A0A287B2Q4

Locations in the PathwayBrowser

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Organelle biogenesis and maintenance (Sus scrofa)

- Cilium Assembly (Sus scrofa)
  - Anchoring of the basal body to the plasma membrane (Sus scrofa)
    - C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole (Sus scrofa)
      - Centrosome:C2CD3:distal appendage proteins [cytosol] (Sus scrofa)
        
        mother centriole:C2CD3 [cytosol] (Sus scrofa)
        
        mother centriole [cytosol] (Sus scrofa)
        
        SFI1 [cytosol] (Sus scrofa)
      - mother centriole:C2CD3 [cytosol] (Sus scrofa)
        
        mother centriole [cytosol] (Sus scrofa)
        
        SFI1 [cytosol] (Sus scrofa)
    - C2CD3 binds the mother centriole (Sus scrofa)
      - mother centriole [cytosol] (Sus scrofa)
        
        SFI1 [cytosol] (Sus scrofa)
      - mother centriole:C2CD3 [cytosol] (Sus scrofa)
        
        mother centriole [cytosol] (Sus scrofa)
        
        SFI1 [cytosol] (Sus scrofa)
    - CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body (Sus scrofa)
      - basal body:transition zone proteins [cytosol] (Sus scrofa)
        
        basal body [cytosol] (Sus scrofa)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Sus scrofa)
        
        SFI1 [cytosol] (Sus scrofa)
      - basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Sus scrofa)
        
        basal body:transition zone proteins [cytosol] (Sus scrofa)
        
        basal body [cytosol] (Sus scrofa)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Sus scrofa)
        
        SFI1 [cytosol] (Sus scrofa)
    - MARK4 binds ODF2 in the centriole (Sus scrofa)
      - Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Sus scrofa)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Sus scrofa)
        
        mother centriole:C2CD3 [cytosol] (Sus scrofa)
        
        mother centriole [cytosol] (Sus scrofa)
        
        SFI1 [cytosol] (Sus scrofa)
      - centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Sus scrofa)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Sus scrofa)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Sus scrofa)
        
        mother centriole:C2CD3 [cytosol] (Sus scrofa)
        
        mother centriole [cytosol] (Sus scrofa)
        
        SFI1 [cytosol] (Sus scrofa)
    - RAB3IP stimulates nucleotide exchange on RAB8A (Sus scrofa)
      - basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Sus scrofa)
        
        basal body:transition zone proteins [cytosol] (Sus scrofa)
        
        basal body [cytosol] (Sus scrofa)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Sus scrofa)
        
        SFI1 [cytosol] (Sus scrofa)
    - Recruitment of transition zone proteins (Sus scrofa)
      - basal body [cytosol] (Sus scrofa)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Sus scrofa)
        
        SFI1 [cytosol] (Sus scrofa)
      - basal body:transition zone proteins [cytosol] (Sus scrofa)
        
        basal body [cytosol] (Sus scrofa)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Sus scrofa)
        
        SFI1 [cytosol] (Sus scrofa)
    - The distal appendage proteins recruit TTBK2 (Sus scrofa)
      - Centrosome:C2CD3:distal appendage proteins [cytosol] (Sus scrofa)
        
        mother centriole:C2CD3 [cytosol] (Sus scrofa)
        
        mother centriole [cytosol] (Sus scrofa)
        
        SFI1 [cytosol] (Sus scrofa)
      - Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Sus scrofa)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Sus scrofa)
        
        mother centriole:C2CD3 [cytosol] (Sus scrofa)
        
        mother centriole [cytosol] (Sus scrofa)
        
        SFI1 [cytosol] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A287B2Q4

Gene Names

SFI1

Reference Genes

ENSEMBL:ENSSSCG00000010031.5

Other Identifiers

100154739

GO:0019902

Ssc.29713.1.A1_at

Participates

as a component of

Inferred From

SFI1 [cytosol] (Homo sapiens)

Cross References

OpenTargets

ENSG00000198089

Ensembl

ENSSSCG00000010031, ENSSSCP00000050691, ENSSSCT00000060735

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