Reactome | PCM1 [cytosol]

PCM1 [cytosol]

Stable Identifier

R-SSC-380308

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

cytosol

Synonyms

PCM1, A0A287BBG5

Locations in the PathwayBrowser

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Organelle biogenesis and maintenance (Sus scrofa)

- Cilium Assembly (Sus scrofa)
  - Anchoring of the basal body to the plasma membrane (Sus scrofa)
    - C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole (Sus scrofa)
      - Centrosome:C2CD3:distal appendage proteins [cytosol] (Sus scrofa)
        
        mother centriole:C2CD3 [cytosol] (Sus scrofa)
        
        mother centriole [cytosol] (Sus scrofa)
        
        PCM1 [cytosol] (Sus scrofa)
      - mother centriole:C2CD3 [cytosol] (Sus scrofa)
        
        mother centriole [cytosol] (Sus scrofa)
        
        PCM1 [cytosol] (Sus scrofa)
    - C2CD3 binds the mother centriole (Sus scrofa)
      - mother centriole [cytosol] (Sus scrofa)
        
        PCM1 [cytosol] (Sus scrofa)
      - mother centriole:C2CD3 [cytosol] (Sus scrofa)
        
        mother centriole [cytosol] (Sus scrofa)
        
        PCM1 [cytosol] (Sus scrofa)
    - CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body (Sus scrofa)
      - basal body:transition zone proteins [cytosol] (Sus scrofa)
        
        basal body [cytosol] (Sus scrofa)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Sus scrofa)
        
        PCM1 [cytosol] (Sus scrofa)
      - basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Sus scrofa)
        
        basal body:transition zone proteins [cytosol] (Sus scrofa)
        
        basal body [cytosol] (Sus scrofa)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Sus scrofa)
        
        PCM1 [cytosol] (Sus scrofa)
    - MARK4 binds ODF2 in the centriole (Sus scrofa)
      - Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Sus scrofa)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Sus scrofa)
        
        mother centriole:C2CD3 [cytosol] (Sus scrofa)
        
        mother centriole [cytosol] (Sus scrofa)
        
        PCM1 [cytosol] (Sus scrofa)
      - centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Sus scrofa)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Sus scrofa)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Sus scrofa)
        
        mother centriole:C2CD3 [cytosol] (Sus scrofa)
        
        mother centriole [cytosol] (Sus scrofa)
        
        PCM1 [cytosol] (Sus scrofa)
    - RAB3IP stimulates nucleotide exchange on RAB8A (Sus scrofa)
      - basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Sus scrofa)
        
        basal body:transition zone proteins [cytosol] (Sus scrofa)
        
        basal body [cytosol] (Sus scrofa)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Sus scrofa)
        
        PCM1 [cytosol] (Sus scrofa)
    - Recruitment of transition zone proteins (Sus scrofa)
      - basal body [cytosol] (Sus scrofa)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Sus scrofa)
        
        PCM1 [cytosol] (Sus scrofa)
      - basal body:transition zone proteins [cytosol] (Sus scrofa)
        
        basal body [cytosol] (Sus scrofa)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Sus scrofa)
        
        PCM1 [cytosol] (Sus scrofa)
    - The distal appendage proteins recruit TTBK2 (Sus scrofa)
      - Centrosome:C2CD3:distal appendage proteins [cytosol] (Sus scrofa)
        
        mother centriole:C2CD3 [cytosol] (Sus scrofa)
        
        mother centriole [cytosol] (Sus scrofa)
        
        PCM1 [cytosol] (Sus scrofa)
      - Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Sus scrofa)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Sus scrofa)
        
        mother centriole:C2CD3 [cytosol] (Sus scrofa)
        
        mother centriole [cytosol] (Sus scrofa)
        
        PCM1 [cytosol] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A287BBG5

Gene Names

PCM1

Reference Genes

ENSEMBL:ENSSSCG00000006994.5

Other Identifiers

100514927

GO:0000242

GO:0001764

GO:0005634

GO:0005635

GO:0005654

GO:0005737

GO:0005813

GO:0005814

GO:0005815

GO:0005829

GO:0005856

GO:0005929

GO:0006886

GO:0007010

GO:0007018

GO:0007098

GO:0022027

GO:0030154

GO:0031122

GO:0031965

GO:0032991

GO:0033365

GO:0034451

GO:0034453

GO:0034454

GO:0035176

GO:0035735

GO:0035869

GO:0036064

GO:0043226

GO:0044782

GO:0045177

GO:0048856

GO:0048870

GO:0050768

GO:0060090

GO:0060271

GO:0061635

GO:0071539

GO:0090316

GO:0097150

GO:0140706

GO:1905515

Ssc.24677.1.S1_at

Participates

as a component of

Inferred From

PCM1 [cytosol] (Homo sapiens)

Cross References

OpenTargets

ENSG00000078674

Ensembl

ENSSSCP00000053680, ENSSSCT00000055887, ENSSSCG00000006994

VGNC

96470

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