Reactome | RXFP2 [plasma membrane]

RXFP2 [plasma membrane]

Stable Identifier

R-SSC-444844

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

plasma membrane

Synonyms

RXFP2, F1RSS8

Locations in the PathwayBrowser

Expand all

Signal Transduction (Sus scrofa)

- Signaling by GPCR (Sus scrofa)
  - GPCR downstream signalling (Sus scrofa)
    - G alpha (s) signalling events (Sus scrofa)
      - Liganded Gs-activating GPCR acts as a GEF for Gs (Sus scrofa)
        
        GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gs [plasma membrane] (Sus scrofa)
        
        RXFP2:RXFP2 ligands [plasma membrane] (Sus scrofa)
        
        RXFP2 [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gs [plasma membrane] (Sus scrofa)
        
        RXFP2:RXFP2 ligands [plasma membrane] (Sus scrofa)
        
        RXFP2 [plasma membrane] (Sus scrofa)
  - GPCR ligand binding (Sus scrofa)
    - Class A/1 (Rhodopsin-like receptors) (Sus scrofa)
      - Peptide ligand-binding receptors (Sus scrofa)
        
        Relaxin receptors (Sus scrofa)
        
        Relaxin receptor 2 binds relaxin 2 and INSL3 (Sus scrofa)
        
        RXFP2 [plasma membrane] (Sus scrofa)
        
        RXFP2:RXFP2 ligands [plasma membrane] (Sus scrofa)
        
        RXFP2 [plasma membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:F1RSS8

Gene Names

RXFP2

Reference Genes

ENSEMBL:ENSSSCG00000009336.4

Other Identifiers

102160691

GO:0004930

GO:0005515

GO:0007165

GO:0007186

GO:0007189

GO:0008584

GO:0016020

GO:0016500

GO:0022414

GO:0023052

GO:0048856

GO:0060089

Participates

as an input of

Relaxin receptor 2 binds relaxin 2 and INSL3 (Sus scrofa)

as a component of

RXFP2:RXFP2 ligands [plasma membrane] (Sus scrofa)

Inferred From

RXFP2 [plasma membrane] (Homo sapiens)

Cross References

OpenTargets

ENSG00000133105

Ensembl

ENSSSCP00000009965, ENSSSCT00000010231, ENSSSCG00000009336

VGNC

92526

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