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NR1H4 [nucleoplasm]
Stable Identifier
R-SSC-5340228
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
nucleoplasm
Synonyms
NR1H4, A0A287A1X6
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Sus scrofa)
RNA Polymerase II Transcription (Sus scrofa)
Generic Transcription Pathway (Sus scrofa)
Nuclear Receptor transcription pathway (Sus scrofa)
Formation of NR-MED1 Coactivator Complex (Sus scrofa)
NR [nucleoplasm] (Sus scrofa)
NR1H4 [nucleoplasm] (Sus scrofa)
NR-MED1 Coactivator Complex [nucleoplasm] (Sus scrofa)
NR [nucleoplasm] (Sus scrofa)
NR1H4 [nucleoplasm] (Sus scrofa)
Formation of NR-NCOR Corepressor Complex (Sus scrofa)
NR [nucleoplasm] (Sus scrofa)
NR1H4 [nucleoplasm] (Sus scrofa)
NR-NCOR CoRepressor Complex [nucleoplasm] (Sus scrofa)
NR [nucleoplasm] (Sus scrofa)
NR1H4 [nucleoplasm] (Sus scrofa)
Metabolism (Sus scrofa)
Biological oxidations (Sus scrofa)
Phase I - Functionalization of compounds (Sus scrofa)
Cytochrome P450 - arranged by substrate type (Sus scrofa)
Endogenous sterols (Sus scrofa)
CYP7A1 7-hydroxylates CHOL (Sus scrofa)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Sus scrofa)
NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Sus scrofa)
NR1H4 [nucleoplasm] (Sus scrofa)
CYP7B1 7-hydroxylates 25OH-CHOL (Sus scrofa)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Sus scrofa)
NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Sus scrofa)
NR1H4 [nucleoplasm] (Sus scrofa)
Metabolism of lipids (Sus scrofa)
Metabolism of steroids (Sus scrofa)
Bile acid and bile salt metabolism (Sus scrofa)
Recycling of bile acids and salts (Sus scrofa)
NR1H4 binds DCA, CDCA, LCHA (Sus scrofa)
NR1H4 [nucleoplasm] (Sus scrofa)
NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Sus scrofa)
NR1H4 [nucleoplasm] (Sus scrofa)
NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 (Sus scrofa)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Sus scrofa)
NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Sus scrofa)
NR1H4 [nucleoplasm] (Sus scrofa)
NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Sus scrofa)
NR1H4 [nucleoplasm] (Sus scrofa)
SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol (Sus scrofa)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Sus scrofa)
NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Sus scrofa)
NR1H4 [nucleoplasm] (Sus scrofa)
Synthesis of bile acids and bile salts (Sus scrofa)
CYP7B1 7-hydroxylates 25OH-CHOL (Sus scrofa)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Sus scrofa)
NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Sus scrofa)
NR1H4 [nucleoplasm] (Sus scrofa)
Synthesis of bile acids and bile salts via 27-hydroxycholesterol (Sus scrofa)
27-hydroxycholesterol is 7alpha-hydroxylated (Sus scrofa)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Sus scrofa)
NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Sus scrofa)
NR1H4 [nucleoplasm] (Sus scrofa)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Sus scrofa)
CYP7A1 7-hydroxylates CHOL (Sus scrofa)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Sus scrofa)
NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Sus scrofa)
NR1H4 [nucleoplasm] (Sus scrofa)
Metabolism of proteins (Sus scrofa)
Post-translational protein modification (Sus scrofa)
SUMOylation (Sus scrofa)
SUMO E3 ligases SUMOylate target proteins (Sus scrofa)
SUMOylation of intracellular receptors (Sus scrofa)
SUMOylation of NR1H4 with SUMO1 (Sus scrofa)
NR1H4:chenodeoxycholate [nucleoplasm] (Sus scrofa)
NR1H4 [nucleoplasm] (Sus scrofa)
External Reference Information
External Reference
UniProt:A0A287A1X6
Gene Names
NR1H4
Reference Genes
ENSEMBL:ENSSSCG00000000875.5
ENSEMBL:ENSSSCG00005045071.1 NR1H4
Other Identifiers
100153960
GO:0000122
GO:0000791
GO:0000977
GO:0000978
GO:0000981
GO:0001221
GO:0001228
GO:0001678
GO:0002376
GO:0003677
GO:0003700
GO:0004879
GO:0005634
GO:0005694
GO:0006351
GO:0006355
GO:0006357
GO:0006366
GO:0006520
GO:0006629
GO:0006954
GO:0007043
GO:0007219
GO:0008206
GO:0008270
GO:0008289
GO:0010804
GO:0010903
GO:0010988
GO:0012501
GO:0023052
GO:0030522
GO:0032052
GO:0032689
GO:0032692
GO:0032703
GO:0032715
GO:0032720
GO:0032740
GO:0034162
GO:0034255
GO:0034330
GO:0035356
GO:0035774
GO:0038181
GO:0038183
GO:0038185
GO:0042593
GO:0042632
GO:0042742
GO:0043066
GO:0043124
GO:0043226
GO:0043235
GO:0043565
GO:0045893
GO:0045944
GO:0046628
GO:0046872
GO:0046965
GO:0048856
GO:0050728
GO:0055089
GO:0060089
GO:0061178
GO:0070328
GO:0071222
GO:0071398
GO:0071417
GO:0071638
GO:0071941
GO:0098542
GO:0140110
GO:1902122
GO:1903413
GO:1904179
GO:1905695
GO:2000213
GO:2001250
Ssc.29683.1.A1_at
Participates
as a component of
NR1H4:chenodeoxycholate [nucleoplasm] (Sus scrofa)
NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Sus scrofa)
as an input of
NR1H4 binds DCA, CDCA, LCHA (Sus scrofa)
as a member of
NR [nucleoplasm] (Sus scrofa)
Other forms of this molecule
NR1H4 [nucleoplasm]
Inferred From
NR1H4 [nucleoplasm]
(Homo sapiens)
NR1H4-1 [nucleoplasm]
(Homo sapiens)
NR1H4-3 [nucleoplasm]
(Homo sapiens)
NR1H4-2 [nucleoplasm]
(Homo sapiens)
NR1H4-4 [nucleoplasm]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000012504
Ensembl
ENSSSCP00000037758
,
ENSSSCT00000050577
,
ENSSSCG00000000875
VGNC
90872
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