Reactome | MRPS18B [mitochondrial inner membrane]

MRPS18B [mitochondrial inner membrane]

Stable Identifier

R-SSC-5368234

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

mitochondrial inner membrane

Synonyms

MRPS18B, Q767K8

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Sus scrofa)

- Translation (Sus scrofa)
  - Mitochondrial translation (Sus scrofa)
    - Mitochondrial translation elongation (Sus scrofa)
      - 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP (Sus scrofa)
        
        55S ribosome:mRNA:tRNA:peptidyl-tRNA at A-site [mitochondrial inner membrane] (Sus scrofa)
        
        55S ribosome [mitochondrial inner membrane] (Sus scrofa)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Sus scrofa)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Sus scrofa)
        
        MRPS18B [mitochondrial inner membrane] (Sus scrofa)
        
        55S ribosome:mRNA:tRNA:peptidyl-tRNA:GFM1:GTP [mitochondrial inner membrane] (Sus scrofa)
        
        55S ribosome [mitochondrial inner membrane] (Sus scrofa)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Sus scrofa)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Sus scrofa)
        
        MRPS18B [mitochondrial inner membrane] (Sus scrofa)
    - Mitochondrial translation termination (Sus scrofa)
      - 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP (Sus scrofa)
        
        55S ribosome:mRNA:peptidyl-tRNA:MTRF1L:GTP [mitochondrial inner membrane] (Sus scrofa)
        
        55S ribosome [mitochondrial inner membrane] (Sus scrofa)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Sus scrofa)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Sus scrofa)
        
        MRPS18B [mitochondrial inner membrane] (Sus scrofa)
        
        55S ribosome:mRNA:tRNA [mitochondrial inner membrane] (Sus scrofa)
        
        55S ribosome [mitochondrial inner membrane] (Sus scrofa)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Sus scrofa)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Sus scrofa)
        
        MRPS18B [mitochondrial inner membrane] (Sus scrofa)
      - Hydrolysis of GTP and dissociation of 28S and 39S subunits (Sus scrofa)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Sus scrofa)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Sus scrofa)
        
        MRPS18B [mitochondrial inner membrane] (Sus scrofa)
        
        55S ribosome:MRRF:GFM2:GTP [mitochondrial inner membrane] (Sus scrofa)
        
        55S ribosome [mitochondrial inner membrane] (Sus scrofa)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Sus scrofa)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Sus scrofa)
        
        MRPS18B [mitochondrial inner membrane] (Sus scrofa)
      - MRRF binds 55S ribosome:mRNA:tRNA (Sus scrofa)
        
        55S ribosome:mRNA:tRNA [mitochondrial inner membrane] (Sus scrofa)
        
        55S ribosome [mitochondrial inner membrane] (Sus scrofa)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Sus scrofa)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Sus scrofa)
        
        MRPS18B [mitochondrial inner membrane] (Sus scrofa)
        
        55S ribosome:mRNA:tRNA:MRRF [mitochondrial inner membrane] (Sus scrofa)
        
        55S ribosome [mitochondrial inner membrane] (Sus scrofa)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Sus scrofa)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Sus scrofa)
        
        MRPS18B [mitochondrial inner membrane] (Sus scrofa)
      - MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA (Sus scrofa)
        
        55S ribosome:mRNA:peptidyl-tRNA at P-site [mitochondrial inner membrane] (Sus scrofa)
        
        55S ribosome [mitochondrial inner membrane] (Sus scrofa)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Sus scrofa)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Sus scrofa)
        
        MRPS18B [mitochondrial inner membrane] (Sus scrofa)
        
        55S ribosome:mRNA:peptidyl-tRNA:MTRF1L:GTP [mitochondrial inner membrane] (Sus scrofa)
        
        55S ribosome [mitochondrial inner membrane] (Sus scrofa)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Sus scrofa)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Sus scrofa)
        
        MRPS18B [mitochondrial inner membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:Q767K8

Gene Names

MRPS18B

Reference Genes

BioGPS Gene:100144465 MRPS18B

ENSEMBL:ENSSSCG00000029425.3 MRPS18B

ENSEMBL:ENSSSCG00005010016.1 MRPS18B

ENSEMBL:ENSSSCG00015032778.1 MRPS18B

ENSEMBL:ENSSSCG00025077792.1

ENSEMBL:ENSSSCG00030061571.1 MRPS18B

ENSEMBL:ENSSSCG00035063512.1 MRPS18B

ENSEMBL:ENSSSCG00045039367.1 MRPS18B

ENSEMBL:ENSSSCG00050016533.1 MRPS18B

ENSEMBL:ENSSSCG00055030616.1 MRPS18B

ENSEMBL:ENSSSCG00060050808.1 MRPS18B

ENSEMBL:ENSSSCG00065056075.1 MRPS18B

ENSEMBL:ENSSSCG00070024659.1 MRPS18B

KEGG Gene (Sus scrofa):100144465 MRPS18B

Monarch:100144465 MRPS18B

NCBI Gene:100144465 MRPS18B

Reference Transcript

RefSeq:NM_001123140.1 MRPS18B

Other Identifiers

100144465

GO:0003735

GO:0005198

GO:0005634

GO:0005654

GO:0005739

GO:0005763

GO:0005840

GO:0006412

GO:0030054

GO:0032543

GO:0043226

GO:0140053

GO:1990904

Ssc.3787.1.S1_at

Participates

as a member of

MRPS18A,B,C [mitochondrial inner membrane] (Sus scrofa)

Inferred From

MRPS18B [mitochondrial inner membrane] (Homo sapiens)

Cross References

RefSeq

NP_001116612.1

OpenTargets

ENSG00000204568

Ensembl

ENSSSCG00000029425, ENSSSCP00000024944, ENSSSCT00000027559

VGNC

90385

PDB

6GAZ, 8OIP, 7NSJ, 7NQL, 6YDP, 8OIN, 5AJ3, 7NQH, 5AJ4, 6GAW, 7NSI, 6YDW