Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyze Data
Species Comparison
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site map
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyze Data
Species Comparison
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site map
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
PSMA7 [cytosol]
Stable Identifier
R-SSC-68736
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
cytosol
Synonyms
A0A287AT18
Locations in the PathwayBrowser
Expand all
Cell Cycle (Sus scrofa)
Cell Cycle Checkpoints (Sus scrofa)
G1/S DNA Damage Checkpoints (Sus scrofa)
p53-Dependent G1/S DNA damage checkpoint (Sus scrofa)
p53-Dependent G1 DNA Damage Response (Sus scrofa)
Stabilization of p53 (Sus scrofa)
Autodegradation of the E3 ubiquitin ligase COP1 (Sus scrofa)
Proteasome mediated degradation of COP1 (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
p53-Independent G1/S DNA damage checkpoint (Sus scrofa)
p53-Independent DNA Damage Response (Sus scrofa)
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A (Sus scrofa)
Proteolytic degradation of ubiquitinated-Cdc25A (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
G2/M Checkpoints (Sus scrofa)
GTSE1 facilitates proteasome-mediated degradation of TP53 (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
Cell Cycle, Mitotic (Sus scrofa)
M Phase (Sus scrofa)
Mitotic Metaphase and Anaphase (Sus scrofa)
Mitotic Anaphase (Sus scrofa)
Separation of Sister Chromatids (Sus scrofa)
Degradation of multiubiquitinated Securin (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
Mitotic G2-G2/M phases (Sus scrofa)
G2/M Transition (Sus scrofa)
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis (Sus scrofa)
Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
Proteasome-mediated degradation of PolyUb-FBXL7 (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
The role of GTSE1 in G2/M progression after G2 checkpoint (Sus scrofa)
GTSE1 facilitates proteasome-mediated degradation of TP53 (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
Regulation of mitotic cell cycle (Sus scrofa)
APC/C-mediated degradation of cell cycle proteins (Sus scrofa)
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (Sus scrofa)
APC/C:Cdh1-mediated degradation of Skp2 (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
Degradation of multiubiquitinated cell cycle proteins (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins (Sus scrofa)
APC/C:Cdc20 mediated degradation of mitotic proteins (Sus scrofa)
APC/C:Cdc20 mediated degradation of Securin (Sus scrofa)
Degradation of multiubiquitinated Securin (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint (Sus scrofa)
Cdc20:Phospho-APC/C mediated degradation of Cyclin A (Sus scrofa)
Degradation multiubiquitinated Cyclin A (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
S Phase (Sus scrofa)
Synthesis of DNA (Sus scrofa)
Switching of origins to a post-replicative state (Sus scrofa)
CDK-mediated phosphorylation and removal of Cdc6 (Sus scrofa)
Ubiquitinated Cdc6 is degraded by the proteasome (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
Orc1 removal from chromatin (Sus scrofa)
Ubiquitinated Orc1 is degraded by the proteasome (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
Ubiquitin-dependent degradation of Cyclin D (Sus scrofa)
Proteasome mediated degradation of Cyclin D1 (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
Cellular responses to external stimuli (Sus scrofa)
Cellular responses to stress (Sus scrofa)
Cellular response to hypoxia (Sus scrofa)
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (Sus scrofa)
Proteasome proteolyzes ub-HIF-alpha (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
DNA Replication (Sus scrofa)
DNA Replication Pre-Initiation (Sus scrofa)
Assembly of the pre-replicative complex (Sus scrofa)
CDT1 association with the CDC6:ORC:origin complex (Sus scrofa)
Ubiquitinated geminin is degraded by the proteasome (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
Synthesis of DNA (Sus scrofa)
Switching of origins to a post-replicative state (Sus scrofa)
CDK-mediated phosphorylation and removal of Cdc6 (Sus scrofa)
Ubiquitinated Cdc6 is degraded by the proteasome (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
Orc1 removal from chromatin (Sus scrofa)
Ubiquitinated Orc1 is degraded by the proteasome (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
Gene expression (Transcription) (Sus scrofa)
RNA Polymerase II Transcription (Sus scrofa)
Generic Transcription Pathway (Sus scrofa)
Transcriptional regulation by RUNX1 (Sus scrofa)
RUNX1 regulates transcription of genes involved in differentiation of HSCs (Sus scrofa)
26S proteasome degrades TP73 polyubiquitinated by ITCH (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
Immune System (Sus scrofa)
Adaptive Immune System (Sus scrofa)
Class I MHC mediated antigen processing & presentation (Sus scrofa)
Antigen processing-Cross presentation (Sus scrofa)
Cross-presentation of soluble exogenous antigens (endosomes) (Sus scrofa)
Proteasomal clevage of exogenous antigen (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
Antigen processing: Ubiquitination & Proteasome degradation (Sus scrofa)
Proteasomal cleavage of substrate (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
Signaling by the B Cell Receptor (BCR) (Sus scrofa)
Downstream signaling events of B Cell Receptor (BCR) (Sus scrofa)
Activation of NF-kappaB in B cells (Sus scrofa)
Ubiquitinated IkB is degraded (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
TCR signaling (Sus scrofa)
Downstream TCR signaling (Sus scrofa)
26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
Cytokine Signaling in Immune system (Sus scrofa)
FLT3 Signaling (Sus scrofa)
RAF/MAP kinase cascade (Sus scrofa)
Regulation of RAS by GAPs (Sus scrofa)
NF1 is degraded by the proteasome (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
Signaling by Interleukins (Sus scrofa)
Interleukin-1 family signaling (Sus scrofa)
Interleukin-1 signaling (Sus scrofa)
Ubiquitinated and phosphorylated IKBA binds to and is degraded by the proteasome complex (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
TNFR2 non-canonical NF-kB pathway (Sus scrofa)
26Sproteasome degrades K48polyUb-NIK (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
NIK-->noncanonical NF-kB signaling (Sus scrofa)
26S proteasome processes p-7S-p100:RELB to form p52:RELB (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
Protesomal degradation of K48polyUb-TRAF3 (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
Innate Immune System (Sus scrofa)
C-type lectin receptors (CLRs) (Sus scrofa)
CLEC7A (Dectin-1) signaling (Sus scrofa)
26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
Dectin-1 mediated noncanonical NF-kB signaling (Sus scrofa)
26S proteasome processes p-7S-p100:RELB to form p52:RELB (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
Fc epsilon receptor (FCERI) signaling (Sus scrofa)
FCERI mediated NF-kB activation (Sus scrofa)
26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
Metabolism (Sus scrofa)
Metabolism of amino acids and derivatives (Sus scrofa)
Metabolism of polyamines (Sus scrofa)
Regulation of ornithine decarboxylase (ODC) (Sus scrofa)
26S proteosome degrades ODC holoenzyme complex (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
Metabolism of RNA (Sus scrofa)
Regulation of mRNA stability by proteins that bind AU-rich elements (Sus scrofa)
AUF1 (hnRNP D0) binds and destabilizes mRNA (Sus scrofa)
AUF1:mRNA complex is destroyed (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
Metabolism of proteins (Sus scrofa)
Post-translational protein modification (Sus scrofa)
Deubiquitination (Sus scrofa)
UCH proteinases (Sus scrofa)
ADRM1 binds 26S proteasome (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
ADRM1:26S proteasome [cytosol] (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
ADRM1:26S proteaseome binds UCHL5 (Sus scrofa)
ADRM1:26S proteasome [cytosol] (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
ADRM1:26S proteasome:UCHL5 [cytosol] (Sus scrofa)
ADRM1:26S proteasome [cytosol] (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
Ub-specific processing proteases (Sus scrofa)
ADRM1:26S proteaseome binds USP14 (Sus scrofa)
ADRM1:26S proteasome [cytosol] (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
ADRM1:26S proteasome:USP14 [cytosol] (Sus scrofa)
ADRM1:26S proteasome [cytosol] (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
Neddylation (Sus scrofa)
26S- and NUB1-mediated degradation of NEDD8, UBD and their conjugates (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
NEDD8,UBD:NUB1:26S proteasome [cytosol] (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
NEDD8 and UBD bind NUB1 and the 26S proteasome (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
NEDD8,UBD:NUB1:26S proteasome [cytosol] (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
Signal Transduction (Sus scrofa)
Intracellular signaling by second messengers (Sus scrofa)
PIP3 activates AKT signaling (Sus scrofa)
PTEN Regulation (Sus scrofa)
Regulation of PTEN stability and activity (Sus scrofa)
Proteasome degrades polyubiquitinated PTEN (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
MAPK family signaling cascades (Sus scrofa)
MAPK1/MAPK3 signaling (Sus scrofa)
RAF/MAP kinase cascade (Sus scrofa)
Regulation of RAS by GAPs (Sus scrofa)
NF1 is degraded by the proteasome (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
MAPK6/MAPK4 signaling (Sus scrofa)
MAPK6 is degraded by the 26S proteasome (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
Signaling by Hedgehog (Sus scrofa)
Hedgehog 'off' state (Sus scrofa)
Degradation of GLI1 by the proteasome (Sus scrofa)
GLI1 is degraded by the proteasome after ubiquitination by ITCH (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
GLI1 is degraded by the proteasome after ubiquitination by beta-TrCP (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
GLI3 is processed to GLI3R by the proteasome (Sus scrofa)
GLI3 is partially degraded by the proteasome to yield the GLI3 repressor (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
Hedgehog 'on' state (Sus scrofa)
ub-GLI is degraded by the proteasome (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
Hedgehog ligand biogenesis (Sus scrofa)
Hh C-terminal fragments are degraded by the proteasome (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
Signaling by WNT (Sus scrofa)
Beta-catenin independent WNT signaling (Sus scrofa)
PCP/CE pathway (Sus scrofa)
Asymmetric localization of PCP proteins (Sus scrofa)
PRICKLE1 is degraded by the proteasome (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
Degradation of beta-catenin by the destruction complex (Sus scrofa)
Degradation of ubiquitinated beta catenin by the proteasome (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
TCF dependent signaling in response to WNT (Sus scrofa)
Degradation of AXIN (Sus scrofa)
Ub-RibC-AXIN is degraded by the proteasome (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
Ubiquitinated AXIN is degraded by the proteasome (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
Degradation of DVL (Sus scrofa)
Ubiquitinated DVL is degraded by the proteasome (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
Ubiquitinated DVL1 is degraded by the proteasome (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
Transport of small molecules (Sus scrofa)
ABC-family proteins mediated transport (Sus scrofa)
misfolded CFTR is degraded by the 26S proteasome (Sus scrofa)
26S proteasome [cytosol] (Sus scrofa)
PSMA7 [cytosol] (Sus scrofa)
External Reference Information
External Reference
UniProt:A0A287AT18
Reference Genes
BioGPS Gene:100626738
ENSEMBL:ENSSSCG00000033332
KEGG Gene (Sus scrofa):100626738
Monarch:100626738
NCBI Gene:100626738
Reference Transcript
RefSeq:NM_001243652.1
Other Identifiers
100626738
AEMK02000106
ENSSSCG00000033332
ENSSSCP00000047002
ENSSSCT00000044737
EntrezGene:100626738
EntrezGene:PSMA7
EntrezGene:PSMA7-202
GO:0000502
GO:0003674
GO:0004175
GO:0004298
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005737
GO:0005839
GO:0006508
GO:0006511
GO:0008150
GO:0008233
GO:0009056
GO:0010498
GO:0010499
GO:0016787
GO:0019773
GO:0032991
GO:0043161
GO:0043226
GO:0051603
GO:0098794
IPR000426
IPR001353
IPR023332
IPR029055
IPR035190
NM_001243652
NP_001230581
PF00227
PF10584
PSMA7
SM00948
Ssc.846.1.S1_at
UPI00021DE044
Participant Of
hasComponent
26S proteasome [cytosol]
Other forms of this molecule
PSMA7 [nucleoplasm]
Inferred From
PSMA7 [cytosol] (Homo sapiens)
Cross References
RefSeq
NP_001230581.1
© 2019
Reactome