Reactome | HNRNPA1 [nucleoplasm]

HNRNPA1 [nucleoplasm]

Stable Identifier

R-SSC-71927

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

nucleoplasm

Synonyms

A0A286ZPE3

Locations in the PathwayBrowser

Expand all

Metabolism of RNA (Sus scrofa)

- Processing of Capped Intron-Containing Pre-mRNA (Sus scrofa)
  - Formation of pre-mRNPs (Sus scrofa)
    - Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
      - shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPA1 [nucleoplasm] (Sus scrofa)
    - capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Sus scrofa)
      - Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPA1 [nucleoplasm] (Sus scrofa)
  - mRNA Splicing (Sus scrofa)
    - mRNA Splicing - Major Pathway (Sus scrofa)
      - Formation of the Spliceosomal Bact complex (Sus scrofa)
        
        Spliceosomal B complex [nucleoplasm] (Sus scrofa)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPA1 [nucleoplasm] (Sus scrofa)
        
        Spliceosomal Bact complex [nucleoplasm] (Sus scrofa)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPA1 [nucleoplasm] (Sus scrofa)
      - Formation of the Spliceosomal C* complex (Sus scrofa)
        
        Spliceosomal C complex [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPA1 [nucleoplasm] (Sus scrofa)
        
        Spliceosomal C* complex [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPA1 [nucleoplasm] (Sus scrofa)
      - Formation of the Spliceosomal E complex (Sus scrofa)
        
        Spliceosomal E complex [nucleoplasm] (Sus scrofa)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPA1 [nucleoplasm] (Sus scrofa)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPA1 [nucleoplasm] (Sus scrofa)
      - Formation of the Spliceosomal P complex and exon ligation (Sus scrofa)
        
        Spliceosomal C* complex [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPA1 [nucleoplasm] (Sus scrofa)
        
        Spliceosomal P complex [nucleoplasm] (Sus scrofa)
        
        spliced mRNA:EJC:CBC complex:Alternative splicing factor [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPA1 [nucleoplasm] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A286ZPE3

Reference Genes

BioGPS Gene:768103

ENSEMBL:ENSSSCG00000000288.5

ENSEMBL:ENSSSCG00005014585.1

Monarch:768103

NCBI Gene:768103

Reference Transcript

RefSeq:XM_005663854.2

Other Identifiers

768103

GO:0003676

GO:0003723

GO:0005634

GO:0005681

GO:0005737

GO:0043226

Participates

as an input of

PTB and hnRNPA1 bind FGFR2 pre-mRNA to repress IIIb splicing and promote formation of FGFR2c mRNA (Sus scrofa)

as a component of

FGFR2 IIIc-specific splicing complex [nucleoplasm] (Sus scrofa)

as a member of

shuttling HNRNPs [nucleoplasm] (Sus scrofa)

Inferred From

HNRNPA1 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_005663911.1

Ensembl

ENSSSCG00000000288, ENSSSCT00000058552, ENSSSCP00000033484

VGNC

88918