Reactome | MAPK3 [nucleoplasm]

MAPK3 [nucleoplasm]

Stable Identifier

R-SSC-73724

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

nucleoplasm

Synonyms

A0A287BLM6

Locations in the PathwayBrowser

Expand all

Immune System (Sus scrofa)

- Cytokine Signaling in Immune system (Sus scrofa)
  - Signaling by Interleukins (Sus scrofa)
    - Interleukin-17 signaling (Sus scrofa)
      - MAP kinase activation (Sus scrofa)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Sus scrofa)
        
        ERK/MAPK targets (Sus scrofa)
        
        ERKs are inactivated (Sus scrofa)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Sus scrofa)
        
        MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Sus scrofa)
        
        MAPK3 dimer [nucleoplasm] (Sus scrofa)
        
        MAPK3 [nucleoplasm] (Sus scrofa)
- Innate Immune System (Sus scrofa)
  - Toll-like Receptor Cascades (Sus scrofa)
    - Toll Like Receptor 10 (TLR10) Cascade (Sus scrofa)
      - MyD88 cascade initiated on plasma membrane (Sus scrofa)
        
        MAP kinase activation (Sus scrofa)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Sus scrofa)
        
        ERK/MAPK targets (Sus scrofa)
        
        ERKs are inactivated (Sus scrofa)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Sus scrofa)
        
        MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Sus scrofa)
        
        MAPK3 dimer [nucleoplasm] (Sus scrofa)
        
        MAPK3 [nucleoplasm] (Sus scrofa)
    - Toll Like Receptor 2 (TLR2) Cascade (Sus scrofa)
      - Toll Like Receptor TLR1:TLR2 Cascade (Sus scrofa)
        
        MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Sus scrofa)
        
        MAP kinase activation (Sus scrofa)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Sus scrofa)
        
        ERK/MAPK targets (Sus scrofa)
        
        ERKs are inactivated (Sus scrofa)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Sus scrofa)
        
        MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Sus scrofa)
        
        MAPK3 dimer [nucleoplasm] (Sus scrofa)
        
        MAPK3 [nucleoplasm] (Sus scrofa)
      - Toll Like Receptor TLR6:TLR2 Cascade (Sus scrofa)
        
        MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Sus scrofa)
        
        MAP kinase activation (Sus scrofa)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Sus scrofa)
        
        ERK/MAPK targets (Sus scrofa)
        
        ERKs are inactivated (Sus scrofa)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Sus scrofa)
        
        MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Sus scrofa)
        
        MAPK3 dimer [nucleoplasm] (Sus scrofa)
        
        MAPK3 [nucleoplasm] (Sus scrofa)
    - Toll Like Receptor 3 (TLR3) Cascade (Sus scrofa)
      - MAP kinase activation (Sus scrofa)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Sus scrofa)
        
        ERK/MAPK targets (Sus scrofa)
        
        ERKs are inactivated (Sus scrofa)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Sus scrofa)
        
        MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Sus scrofa)
        
        MAPK3 dimer [nucleoplasm] (Sus scrofa)
        
        MAPK3 [nucleoplasm] (Sus scrofa)
    - Toll Like Receptor 4 (TLR4) Cascade (Sus scrofa)
      - MyD88-independent TLR4 cascade (Sus scrofa)
        
        TRIF(TICAM1)-mediated TLR4 signaling (Sus scrofa)
        
        MAP kinase activation (Sus scrofa)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Sus scrofa)
        
        ERK/MAPK targets (Sus scrofa)
        
        ERKs are inactivated (Sus scrofa)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Sus scrofa)
        
        MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Sus scrofa)
        
        MAPK3 dimer [nucleoplasm] (Sus scrofa)
        
        MAPK3 [nucleoplasm] (Sus scrofa)
      - MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Sus scrofa)
        
        MAP kinase activation (Sus scrofa)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Sus scrofa)
        
        ERK/MAPK targets (Sus scrofa)
        
        ERKs are inactivated (Sus scrofa)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Sus scrofa)
        
        MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Sus scrofa)
        
        MAPK3 dimer [nucleoplasm] (Sus scrofa)
        
        MAPK3 [nucleoplasm] (Sus scrofa)
    - Toll Like Receptor 5 (TLR5) Cascade (Sus scrofa)
      - MyD88 cascade initiated on plasma membrane (Sus scrofa)
        
        MAP kinase activation (Sus scrofa)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Sus scrofa)
        
        ERK/MAPK targets (Sus scrofa)
        
        ERKs are inactivated (Sus scrofa)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Sus scrofa)
        
        MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Sus scrofa)
        
        MAPK3 dimer [nucleoplasm] (Sus scrofa)
        
        MAPK3 [nucleoplasm] (Sus scrofa)
    - Toll Like Receptor 7/8 (TLR7/8) Cascade (Sus scrofa)
      - MyD88 dependent cascade initiated on endosome (Sus scrofa)
        
        TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Sus scrofa)
        
        MAP kinase activation (Sus scrofa)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Sus scrofa)
        
        ERK/MAPK targets (Sus scrofa)
        
        ERKs are inactivated (Sus scrofa)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Sus scrofa)
        
        MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Sus scrofa)
        
        MAPK3 dimer [nucleoplasm] (Sus scrofa)
        
        MAPK3 [nucleoplasm] (Sus scrofa)
    - Toll Like Receptor 9 (TLR9) Cascade (Sus scrofa)
      - MyD88 dependent cascade initiated on endosome (Sus scrofa)
        
        TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Sus scrofa)
        
        MAP kinase activation (Sus scrofa)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Sus scrofa)
        
        ERK/MAPK targets (Sus scrofa)
        
        ERKs are inactivated (Sus scrofa)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Sus scrofa)
        
        MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Sus scrofa)
        
        MAPK3 dimer [nucleoplasm] (Sus scrofa)
        
        MAPK3 [nucleoplasm] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A287BLM6

Reference Genes

ENSEMBL:ENSSSCG00000040682

Other Identifiers

445013

GO:0000166

GO:0000187

GO:0001784

GO:0001934

GO:0002376

GO:0002720

GO:0003674

GO:0004672

GO:0004674

GO:0004707

GO:0004708

GO:0005524

GO:0005575

GO:0005622

GO:0005634

GO:0005635

GO:0005737

GO:0005829

GO:0005886

GO:0005901

GO:0006259

GO:0006351

GO:0006464

GO:0006468

GO:0006914

GO:0006950

GO:0006974

GO:0006975

GO:0007049

GO:0007165

GO:0007166

GO:0008150

GO:0008283

GO:0009056

GO:0009058

GO:0009790

GO:0009887

GO:0010468

GO:0010628

GO:0010759

GO:0014032

GO:0016301

GO:0016310

GO:0016740

GO:0019233

GO:0019899

GO:0019902

GO:0030154

GO:0030278

GO:0030509

GO:0030641

GO:0030878

GO:0031143

GO:0031281

GO:0031663

GO:0032212

GO:0032496

GO:0033129

GO:0034198

GO:0034614

GO:0034641

GO:0035066

GO:0035556

GO:0038083

GO:0040011

GO:0042473

GO:0042592

GO:0042802

GO:0043167

GO:0043226

GO:0043330

GO:0045944

GO:0048538

GO:0048646

GO:0048856

GO:0048870

GO:0050877

GO:0051090

GO:0051216

GO:0051276

GO:0051403

GO:0051973

GO:0060020

GO:0060324

GO:0060425

GO:0060440

GO:0061308

GO:0070371

GO:0070374

GO:0070498

GO:0070849

GO:0071260

GO:0071276

GO:0071356

GO:0120041

GO:1903351

GO:1904355

GO:1904417

GO:1905050

GO:2000657

Ssc.5924.1.S1_at

Participant Of

hasMember

MAPK monomers and dimers [nucleoplasm]

hasComponent

MAPK3 dimer [nucleoplasm]

Other forms of this molecule

phospho-p-Y204-MAPK3-3 [cytosol]

MAPK3 [cytosol]

phospho-p-T202,Y204-MAPK3 [cytosol]

phospho-p-T202,Y204-MAPK3 [nucleoplasm]

Inferred From

MAPK3 [nucleoplasm] (Homo sapiens)

Cross References

Ensembl

ENSSSCG00000040682, ENSSSCT00000060796, ENSSSCP00000057520

VGNC

90003

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