Reactome | GPR143 [plasma membrane]

GPR143 [plasma membrane]

Stable Identifier

R-SSC-8851292

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

plasma membrane

Synonyms

GPR143, A0A286ZZS9

Locations in the PathwayBrowser

Expand all

Signal Transduction (Sus scrofa)

- Signaling by GPCR (Sus scrofa)
  - GPCR downstream signalling (Sus scrofa)
    - G alpha (q) signalling events (Sus scrofa)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        GPR143:L-Dopa [plasma membrane] (Sus scrofa)
        
        Homologues of GPR143 [plasma membrane] (Sus scrofa)
        
        GPR143 [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        GPR143:L-Dopa [plasma membrane] (Sus scrofa)
        
        Homologues of GPR143 [plasma membrane] (Sus scrofa)
        
        GPR143 [plasma membrane] (Sus scrofa)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        GPR143:L-Dopa [plasma membrane] (Sus scrofa)
        
        Homologues of GPR143 [plasma membrane] (Sus scrofa)
        
        GPR143 [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        GPR143:L-Dopa [plasma membrane] (Sus scrofa)
        
        Homologues of GPR143 [plasma membrane] (Sus scrofa)
        
        GPR143 [plasma membrane] (Sus scrofa)
      - The Ligand:GPCR:Gq complex dissociates (Sus scrofa)
        
        GPCRs that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        Homologues of GPR143 [plasma membrane] (Sus scrofa)
        
        GPR143 [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        GPR143:L-Dopa [plasma membrane] (Sus scrofa)
        
        Homologues of GPR143 [plasma membrane] (Sus scrofa)
        
        GPR143 [plasma membrane] (Sus scrofa)
  - GPCR ligand binding (Sus scrofa)
    - Class A/1 (Rhodopsin-like receptors) (Sus scrofa)
      - Amine ligand-binding receptors (Sus scrofa)
        
        GPR143 binds L-Dopa (Sus scrofa)
        
        GPR143:L-Dopa [plasma membrane] (Sus scrofa)
        
        Homologues of GPR143 [plasma membrane] (Sus scrofa)
        
        GPR143 [plasma membrane] (Sus scrofa)
        
        Homologues of GPR143 [plasma membrane] (Sus scrofa)
        
        GPR143 [plasma membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A286ZZS9

Gene Names

GPR143

Reference Genes

BioGPS Gene:100624736 GPR143

ENSEMBL:ENSSSCG00000036341

KEGG Gene (Sus scrofa):100624736 GPR143

Monarch:100624736 GPR143

NCBI Gene:100624736 GPR143

Reference Transcript

RefSeq:XM_003360225.3 GPR143

Other Identifiers

100624736

GO:0003674

GO:0004930

GO:0005575

GO:0005622

GO:0005737

GO:0005886

GO:0007165

GO:0007186

GO:0007218

GO:0008150

GO:0016020

GO:0016021

GO:0031410

GO:0032438

GO:0033162

GO:0035240

GO:0035643

GO:0043167

GO:0043226

GO:0043473

GO:0050848

GO:0072544

GO:0072545

Ssc.27266.1.S1_at

Participant Of

hasMember

Homologues of GPR143 [plasma membrane]

Inferred From

GPR143 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_003360273.2

OpenTargets

ENSG00000101850

Ensembl

ENSSSCP00000037012, ENSSSCT00000058052, ENSSSCG00000036341