Reactome | BTBD1 [cytosol]

BTBD1 [cytosol]

Stable Identifier

R-SSC-8851650

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

cytosol

Synonyms

BTBD1, F1RIB2

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Sus scrofa)

- Post-translational protein modification (Sus scrofa)
  - Neddylation (Sus scrofa)
    - AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex (Sus scrofa)
      - NEDD8-AcM-UBE2M:CRL3 E3 ubiquitin ligase :DCUN1D1,2,4,5 [cytosol] (Sus scrofa)
        
        CRL3 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        RBX1:CUL3:BTB [cytosol] (Sus scrofa)
        
        BTB proteins [cytosol] (Sus scrofa)
        
        BTBD1 [cytosol] (Sus scrofa)
      - NEDD8-CRL3 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Sus scrofa)
        
        NEDD8-CUL3:RBX1:BTB [cytosol] (Sus scrofa)
        
        BTB proteins [cytosol] (Sus scrofa)
        
        BTBD1 [cytosol] (Sus scrofa)
    - CAND1 binds cytosolic CRL E3 ubiquitin ligases (Sus scrofa)
      - CRL E3 ubiquitin ligase:CAND1 [cytosol] (Sus scrofa)
        
        CRL E3 ubiquitin ligases [cytosol] (Sus scrofa)
        
        RBX1:CUL3:BTB [cytosol] (Sus scrofa)
        
        BTB proteins [cytosol] (Sus scrofa)
        
        BTBD1 [cytosol] (Sus scrofa)
      - CRL E3 ubiquitin ligases [cytosol] (Sus scrofa)
        
        RBX1:CUL3:BTB [cytosol] (Sus scrofa)
        
        BTB proteins [cytosol] (Sus scrofa)
        
        BTBD1 [cytosol] (Sus scrofa)
    - COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes (Sus scrofa)
      - CRL E3 ubiquitin ligase:CAND1 [cytosol] (Sus scrofa)
        
        CRL E3 ubiquitin ligases [cytosol] (Sus scrofa)
        
        RBX1:CUL3:BTB [cytosol] (Sus scrofa)
        
        BTB proteins [cytosol] (Sus scrofa)
        
        BTBD1 [cytosol] (Sus scrofa)
      - CRL E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        CRL3 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        RBX1:CUL3:BTB [cytosol] (Sus scrofa)
        
        BTB proteins [cytosol] (Sus scrofa)
        
        BTBD1 [cytosol] (Sus scrofa)
    - COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Sus scrofa)
      - CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Sus scrofa)
        
        CRL3 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Sus scrofa)
        
        RBX1:CUL3:BTB [cytosol] (Sus scrofa)
        
        BTB proteins [cytosol] (Sus scrofa)
        
        BTBD1 [cytosol] (Sus scrofa)
      - NEDD8 CRL E3 ubiquitin ligases:COMMDs:CCDC22:DCUN1Ds [cytosol] (Sus scrofa)
        
        NEDD8-CRL3 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Sus scrofa)
        
        NEDD8-CUL3:RBX1:BTB [cytosol] (Sus scrofa)
        
        BTB proteins [cytosol] (Sus scrofa)
        
        BTBD1 [cytosol] (Sus scrofa)

External Reference Information

External Reference

UniProt:F1RIB2

Gene Names

BTBD1

Reference Genes

BioGPS Gene:100154013 BTBD1

ENSEMBL:ENSSSCG00000001801.4

KEGG Gene (Sus scrofa):100154013 BTBD1

Monarch:100154013 BTBD1

NCBI Gene:100154013 BTBD1

Reference Transcript

RefSeq:XM_001929165.4 BTBD1

Other Identifiers

100154013

GO:0000932

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0022008

GO:0030154

GO:0032991

GO:0036464

GO:0042802

GO:0043226

GO:0048856

GO:0097602

Ssc.22958.1.S1_a_at

Participates

as a candidate of

E3 ligases in proteasomal degradation [cytosol] (Sus scrofa)

as a member of

BTB proteins [cytosol] (Sus scrofa)

Inferred From

BTBD1 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_001929200.1

OpenTargets

ENSG00000064726

Ensembl

ENSSSCG00000001801, ENSSSCP00000001968, ENSSSCT00000002017

VGNC

85900

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