Reactome | FEM1A [cytosol]

FEM1A [cytosol]

Stable Identifier

R-SSC-8863141

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

cytosol

Synonyms

FEM1A, A0A287A0D5

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Sus scrofa)

- Post-translational protein modification (Sus scrofa)
  - Neddylation (Sus scrofa)
    - AcM-UBE2M transfers NEDD8 to CRL2 E3 ubiquitin ligase complex (Sus scrofa)
      - NEDD8-AcM-UBE2M:CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Sus scrofa)
        
        CRL2 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        CRL2 E3 ubiquitin ligase [cytosol] (Sus scrofa)
        
        CUL2-box protein [cytosol] (Sus scrofa)
        
        FEM1A [cytosol] (Sus scrofa)
      - NEDD8-CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Sus scrofa)
        
        NEDD8-CRL2 E3 ligase complex [cytosol] (Sus scrofa)
        
        CUL2-box protein [cytosol] (Sus scrofa)
        
        FEM1A [cytosol] (Sus scrofa)
    - CAND1 binds cytosolic CRL E3 ubiquitin ligases (Sus scrofa)
      - CRL E3 ubiquitin ligase:CAND1 [cytosol] (Sus scrofa)
        
        CRL E3 ubiquitin ligases [cytosol] (Sus scrofa)
        
        CRL2 E3 ubiquitin ligase [cytosol] (Sus scrofa)
        
        CUL2-box protein [cytosol] (Sus scrofa)
        
        FEM1A [cytosol] (Sus scrofa)
      - CRL E3 ubiquitin ligases [cytosol] (Sus scrofa)
        
        CRL2 E3 ubiquitin ligase [cytosol] (Sus scrofa)
        
        CUL2-box protein [cytosol] (Sus scrofa)
        
        FEM1A [cytosol] (Sus scrofa)
    - COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes (Sus scrofa)
      - CRL E3 ubiquitin ligase:CAND1 [cytosol] (Sus scrofa)
        
        CRL E3 ubiquitin ligases [cytosol] (Sus scrofa)
        
        CRL2 E3 ubiquitin ligase [cytosol] (Sus scrofa)
        
        CUL2-box protein [cytosol] (Sus scrofa)
        
        FEM1A [cytosol] (Sus scrofa)
      - CRL E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        CRL2 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        CRL2 E3 ubiquitin ligase [cytosol] (Sus scrofa)
        
        CUL2-box protein [cytosol] (Sus scrofa)
        
        FEM1A [cytosol] (Sus scrofa)
    - COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Sus scrofa)
      - CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Sus scrofa)
        
        CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Sus scrofa)
        
        CRL2 E3 ubiquitin ligase [cytosol] (Sus scrofa)
        
        CUL2-box protein [cytosol] (Sus scrofa)
        
        FEM1A [cytosol] (Sus scrofa)
      - NEDD8 CRL E3 ubiquitin ligases:COMMDs:CCDC22:DCUN1Ds [cytosol] (Sus scrofa)
        
        NEDD8-CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Sus scrofa)
        
        NEDD8-CRL2 E3 ligase complex [cytosol] (Sus scrofa)
        
        CUL2-box protein [cytosol] (Sus scrofa)
        
        FEM1A [cytosol] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A287A0D5

Gene Names

FEM1A

Reference Genes

ENSEMBL:ENSSSCG00000037153.1

Other Identifiers

100625091

GO:0005515

GO:0005739

GO:0006954

GO:0030163

GO:0031462

GO:0031867

GO:0043226

GO:0050728

GO:0060090

GO:0140627

GO:1990756

Participates

as a member of

CUL2-box protein [cytosol] (Sus scrofa)

Inferred From

FEM1A [cytosol] (Homo sapiens)

Cross References

OpenTargets

ENSG00000141965

Ensembl

ENSSSCP00000037208, ENSSSCG00000037153, ENSSSCT00000039016

VGNC

88082

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