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phospho-MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane]
Stable Identifier
R-SSC-8875181
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
plasma membrane
Synonyms
Q2QLE0
Locations in the PathwayBrowser
Expand all
Signal Transduction (Sus scrofa)
Signaling by Receptor Tyrosine Kinases (Sus scrofa)
Signaling by MET (Sus scrofa)
Negative regulation of MET activity (Sus scrofa)
CBL monoubiquitinates activated MET (Sus scrofa)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-MET dimer:p-Y-CBL) [plasma membrane] (Sus scrofa)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL [plasma membrane] (Sus scrofa)
HGF:MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Sus scrofa)
HGF dimer:MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane] (Sus scrofa)
phospho-MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane] (Sus scrofa)
CBL recruits CIN85:endophilin to ubiquitinated MET (Sus scrofa)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-MET dimer:p-Y-CBL) [plasma membrane] (Sus scrofa)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL [plasma membrane] (Sus scrofa)
HGF:MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Sus scrofa)
HGF dimer:MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane] (Sus scrofa)
phospho-MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane] (Sus scrofa)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-METdimer:p-Y-CBL):CIN85:endophillin [plasma membrane] (Sus scrofa)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-MET dimer:p-Y-CBL) [plasma membrane] (Sus scrofa)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL [plasma membrane] (Sus scrofa)
HGF:MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Sus scrofa)
HGF dimer:MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane] (Sus scrofa)
phospho-MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane] (Sus scrofa)
EPS15 and HGS bind ubiquitinated MET (Sus scrofa)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-METdimer:p-Y-CBL):CIN85:endophillin,(MET:Ub-LRIG1) [plasma membrane] (Sus scrofa)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-METdimer:p-Y-CBL):CIN85:endophillin [plasma membrane] (Sus scrofa)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-MET dimer:p-Y-CBL) [plasma membrane] (Sus scrofa)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL [plasma membrane] (Sus scrofa)
HGF:MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Sus scrofa)
HGF dimer:MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane] (Sus scrofa)
phospho-MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane] (Sus scrofa)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-METdimer:p-Y-CBL):CIN85:endophillin:EPS15:HGS:STAM,(MET:Ub-LRIG1:EPS15:HGS:STAM) [plasma membrane] (Sus scrofa)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-METdimer:p-Y-CBL):CIN85:endophillin,(MET:Ub-LRIG1) [plasma membrane] (Sus scrofa)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-METdimer:p-Y-CBL):CIN85:endophillin [plasma membrane] (Sus scrofa)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-MET dimer:p-Y-CBL) [plasma membrane] (Sus scrofa)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL [plasma membrane] (Sus scrofa)
HGF:MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Sus scrofa)
HGF dimer:MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane] (Sus scrofa)
phospho-MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane] (Sus scrofa)
External Reference Information
External Reference
UniProt:Q2QLE0
Reference Genes
BioGPS Gene:654328
ENSEMBL:ENSSSCG00000024351.4
ENSEMBL:ENSSSCG00025071107.1
ENSEMBL:ENSSSCG00030053322.1
ENSEMBL:ENSSSCG00035033646.1
ENSEMBL:ENSSSCG00040035636.1
ENSEMBL:ENSSSCG00055019459.1
ENSEMBL:ENSSSCG00070028695.1
KEGG Gene (Sus scrofa):654328
Monarch:654328
NCBI Gene:654328
Reference Transcript
RefSeq:NM_001038008.1
Other Identifiers
654328
GO:0001886
GO:0003824
GO:0004672
GO:0004713
GO:0004714
GO:0005515
GO:0005524
GO:0005886
GO:0006351
GO:0006355
GO:0006468
GO:0007010
GO:0007169
GO:0009925
GO:0012501
GO:0016020
GO:0016740
GO:0017154
GO:0019903
GO:0023052
GO:0030154
GO:0031116
GO:0035024
GO:0036211
GO:0042802
GO:0045944
GO:0048754
GO:0048856
GO:0048870
GO:0050918
GO:0051497
GO:0060089
GO:0061436
GO:0065003
GO:0070495
GO:0071526
GO:0140096
GO:1901299
GO:2001028
Ssc.9275.1.A1_at
Participates
as a component of
HGF dimer:MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane] (Sus scrofa)
Other forms of this molecule
phospho-MonoUb-K,p-Y1003,4Y-MET [plasma membrane]
phospho-p-Y1003,4Y-MET [plasma membrane]
phospho-p-Y1349,Y1356-MET [plasma membrane]
phospho-p-Y1234,Y1235,Y1356-MET [plasma membrane]
MET [plasma membrane]
phospho-p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane]
Inferred From
MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane]
(Homo sapiens)
Modified Residues
Name
O4'-phospho-L-tyrosine at 1234 (in Homo sapiens)
Coordinate
1234
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1235 (in Homo sapiens)
Coordinate
1235
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1349 (in Homo sapiens)
Coordinate
1349
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1356 (in Homo sapiens)
Coordinate
1356
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
ubiquitinylated lysine (Ub [cytosol]) at unknown position
Modification
Ub [cytosol]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
RefSeq
NP_001033097.1
Ensembl
ENSSSCG00000024351
,
ENSSSCP00000017620
,
ENSSSCT00000018110
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