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USP18 [cytosol]
Stable Identifier
R-SSC-912325
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
cytosol
Synonyms
USP18, A0A287A210
Locations in the PathwayBrowser
Expand all
Immune System (Sus scrofa)
Cytokine Signaling in Immune system (Sus scrofa)
Interferon Signaling (Sus scrofa)
Antiviral mechanism by IFN-stimulated genes (Sus scrofa)
ISG15 antiviral mechanism (Sus scrofa)
Regulation of protein ISGylation by ISG15 deconjugating enzyme USP18 (Sus scrofa)
USP18 [cytosol] (Sus scrofa)
Interferon alpha/beta signaling (Sus scrofa)
Regulation of IFNA/IFNB signaling (Sus scrofa)
UBP43 binds IFNAR2 and prevents JAK1 interaction (Sus scrofa)
IFNAR2c:UBP43 [plasma membrane] (Sus scrofa)
USP18 [cytosol] (Sus scrofa)
USP18 [cytosol] (Sus scrofa)
Signaling by Interleukins (Sus scrofa)
Interleukin-1 family signaling (Sus scrofa)
Interleukin-1 signaling (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
Regulation of NF-kappa B signaling (Sus scrofa)
USP18 binds IKBKG within IKK complex (Sus scrofa)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Sus scrofa)
USP18 [cytosol] (Sus scrofa)
USP18 [cytosol] (Sus scrofa)
Ubiquitination of IKBKG by TRAF6 (Sus scrofa)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Sus scrofa)
USP18 [cytosol] (Sus scrofa)
Innate Immune System (Sus scrofa)
Toll-like Receptor Cascades (Sus scrofa)
Toll Like Receptor 10 (TLR10) Cascade (Sus scrofa)
MyD88 cascade initiated on plasma membrane (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
Regulation of NF-kappa B signaling (Sus scrofa)
USP18 binds IKBKG within IKK complex (Sus scrofa)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Sus scrofa)
USP18 [cytosol] (Sus scrofa)
USP18 [cytosol] (Sus scrofa)
Ubiquitination of IKBKG by TRAF6 (Sus scrofa)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Sus scrofa)
USP18 [cytosol] (Sus scrofa)
Toll Like Receptor 2 (TLR2) Cascade (Sus scrofa)
Toll Like Receptor TLR1:TLR2 Cascade (Sus scrofa)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
Regulation of NF-kappa B signaling (Sus scrofa)
USP18 binds IKBKG within IKK complex (Sus scrofa)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Sus scrofa)
USP18 [cytosol] (Sus scrofa)
USP18 [cytosol] (Sus scrofa)
Ubiquitination of IKBKG by TRAF6 (Sus scrofa)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Sus scrofa)
USP18 [cytosol] (Sus scrofa)
Toll Like Receptor TLR6:TLR2 Cascade (Sus scrofa)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
Regulation of NF-kappa B signaling (Sus scrofa)
USP18 binds IKBKG within IKK complex (Sus scrofa)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Sus scrofa)
USP18 [cytosol] (Sus scrofa)
USP18 [cytosol] (Sus scrofa)
Ubiquitination of IKBKG by TRAF6 (Sus scrofa)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Sus scrofa)
USP18 [cytosol] (Sus scrofa)
Toll Like Receptor 3 (TLR3) Cascade (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
Regulation of NF-kappa B signaling (Sus scrofa)
USP18 binds IKBKG within IKK complex (Sus scrofa)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Sus scrofa)
USP18 [cytosol] (Sus scrofa)
USP18 [cytosol] (Sus scrofa)
Ubiquitination of IKBKG by TRAF6 (Sus scrofa)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Sus scrofa)
USP18 [cytosol] (Sus scrofa)
Toll Like Receptor 4 (TLR4) Cascade (Sus scrofa)
MyD88-independent TLR4 cascade (Sus scrofa)
TRIF (TICAM1)-mediated TLR4 signaling (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
Regulation of NF-kappa B signaling (Sus scrofa)
USP18 binds IKBKG within IKK complex (Sus scrofa)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Sus scrofa)
USP18 [cytosol] (Sus scrofa)
USP18 [cytosol] (Sus scrofa)
Ubiquitination of IKBKG by TRAF6 (Sus scrofa)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Sus scrofa)
USP18 [cytosol] (Sus scrofa)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
Regulation of NF-kappa B signaling (Sus scrofa)
USP18 binds IKBKG within IKK complex (Sus scrofa)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Sus scrofa)
USP18 [cytosol] (Sus scrofa)
USP18 [cytosol] (Sus scrofa)
Ubiquitination of IKBKG by TRAF6 (Sus scrofa)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Sus scrofa)
USP18 [cytosol] (Sus scrofa)
Toll Like Receptor 5 (TLR5) Cascade (Sus scrofa)
MyD88 cascade initiated on plasma membrane (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
Regulation of NF-kappa B signaling (Sus scrofa)
USP18 binds IKBKG within IKK complex (Sus scrofa)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Sus scrofa)
USP18 [cytosol] (Sus scrofa)
USP18 [cytosol] (Sus scrofa)
Ubiquitination of IKBKG by TRAF6 (Sus scrofa)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Sus scrofa)
USP18 [cytosol] (Sus scrofa)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Sus scrofa)
MyD88 dependent cascade initiated on endosome (Sus scrofa)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
Regulation of NF-kappa B signaling (Sus scrofa)
USP18 binds IKBKG within IKK complex (Sus scrofa)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Sus scrofa)
USP18 [cytosol] (Sus scrofa)
USP18 [cytosol] (Sus scrofa)
Ubiquitination of IKBKG by TRAF6 (Sus scrofa)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Sus scrofa)
USP18 [cytosol] (Sus scrofa)
Toll Like Receptor 9 (TLR9) Cascade (Sus scrofa)
MyD88 dependent cascade initiated on endosome (Sus scrofa)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
Regulation of NF-kappa B signaling (Sus scrofa)
USP18 binds IKBKG within IKK complex (Sus scrofa)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Sus scrofa)
USP18 [cytosol] (Sus scrofa)
USP18 [cytosol] (Sus scrofa)
Ubiquitination of IKBKG by TRAF6 (Sus scrofa)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Sus scrofa)
USP18 [cytosol] (Sus scrofa)
Metabolism of proteins (Sus scrofa)
Post-translational protein modification (Sus scrofa)
Deubiquitination (Sus scrofa)
Ub-specific processing proteases (Sus scrofa)
USP18 deubiquitinates TAK1:TAB1 (Sus scrofa)
USP18 [cytosol] (Sus scrofa)
USP18:MAP3K7:TAB1 [cytosol] (Sus scrofa)
USP18 [cytosol] (Sus scrofa)
USP18:PolyUb-MAP3K7:TAB1 [cytosol] (Sus scrofa)
USP18 [cytosol] (Sus scrofa)
External Reference Information
External Reference
UniProt:A0A287A210
Gene Names
USP18
Reference Genes
ENSEMBL:ENSSSCG00000000774.5
Other Identifiers
396777
GO:0002376
GO:0005634
GO:0005829
GO:0006954
GO:0023052
GO:0043226
GO:0043231
GO:0050727
GO:0060090
GO:0060339
GO:0098542
GO:0140374
Ssc.336.1.S1_at
Participates
as a component of
USP18:MAP3K7:TAB1 [cytosol] (Sus scrofa)
USP18:PolyUb-MAP3K7:TAB1 [cytosol] (Sus scrofa)
IFNAR2c:UBP43 [plasma membrane] (Sus scrofa)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Sus scrofa)
as an input of
UBP43 binds IFNAR2 and prevents JAK1 interaction (Sus scrofa)
USP18 binds IKBKG within IKK complex (Sus scrofa)
Inferred From
USP18 [cytosol]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000184979
Ensembl
ENSSSCG00000000774
,
ENSSSCP00000040529
,
ENSSSCT00000065704
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