Reactome | MCHR2 [plasma membrane]

MCHR2 [plasma membrane]

Stable Identifier

R-SSC-947674

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

plasma membrane

Synonyms

MCHR2, F1RXX8

Locations in the PathwayBrowser

Expand all

Signal Transduction (Sus scrofa)

- Signaling by GPCR (Sus scrofa)
  - GPCR downstream signalling (Sus scrofa)
    - G alpha (i) signalling events (Sus scrofa)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2:PMCH(147-165) [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2 [plasma membrane] (Sus scrofa)
        
        MCHR2 [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2:PMCH(147-165) [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2 [plasma membrane] (Sus scrofa)
        
        MCHR2 [plasma membrane] (Sus scrofa)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2:PMCH(147-165) [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2 [plasma membrane] (Sus scrofa)
        
        MCHR2 [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2:PMCH(147-165) [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2 [plasma membrane] (Sus scrofa)
        
        MCHR2 [plasma membrane] (Sus scrofa)
      - The Ligand:GPCR:Gi complex dissociates (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2:PMCH(147-165) [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2 [plasma membrane] (Sus scrofa)
        
        MCHR2 [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2:PMCH(147-165) [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2 [plasma membrane] (Sus scrofa)
        
        MCHR2 [plasma membrane] (Sus scrofa)
    - G alpha (q) signalling events (Sus scrofa)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2:PMCH(147-165) [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2 [plasma membrane] (Sus scrofa)
        
        MCHR2 [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2:PMCH(147-165) [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2 [plasma membrane] (Sus scrofa)
        
        MCHR2 [plasma membrane] (Sus scrofa)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2:PMCH(147-165) [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2 [plasma membrane] (Sus scrofa)
        
        MCHR2 [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2:PMCH(147-165) [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2 [plasma membrane] (Sus scrofa)
        
        MCHR2 [plasma membrane] (Sus scrofa)
      - The Ligand:GPCR:Gq complex dissociates (Sus scrofa)
        
        GPCRs that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2 [plasma membrane] (Sus scrofa)
        
        MCHR2 [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2:PMCH(147-165) [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2 [plasma membrane] (Sus scrofa)
        
        MCHR2 [plasma membrane] (Sus scrofa)
  - GPCR ligand binding (Sus scrofa)
    - Class A/1 (Rhodopsin-like receptors) (Sus scrofa)
      - Peptide ligand-binding receptors (Sus scrofa)
        
        Melanin-concentrating hormone receptors bind MCH (Sus scrofa)
        
        MCHR1,MCHR2 [plasma membrane] (Sus scrofa)
        
        MCHR2 [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2:PMCH(147-165) [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2 [plasma membrane] (Sus scrofa)
        
        MCHR2 [plasma membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:F1RXX8

Gene Names

MCHR2

Reference Genes

ENSEMBL:ENSSSCG00000004356.4

Reference Transcript

Other Identifiers

733682

GO:0004930

GO:0005886

GO:0007165

GO:0007186

GO:0007218

GO:0008528

GO:0016020

GO:0023052

GO:0060089

Participates

as a member of

MCHR1,MCHR2 [plasma membrane] (Sus scrofa)

Inferred From

MCHR2 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_005659387.1, XP_005659388.1

OpenTargets

ENSG00000152034

Ensembl

ENSSSCP00000004699, ENSSSCG00000004356, ENSSSCT00000004813

VGNC

90070

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