Reactome | WSB1 [cytosol]

WSB1 [cytosol]

Stable Identifier

R-SSC-976016

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

cytosol

Synonyms

WSB1, A0A286ZUC3

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Sus scrofa)

- Post-translational protein modification (Sus scrofa)
  - Neddylation (Sus scrofa)
    - CAND1 binds cytosolic CRL E3 ubiquitin ligases (Sus scrofa)
      - CRL E3 ubiquitin ligase:CAND1 [cytosol] (Sus scrofa)
        
        CRL E3 ubiquitin ligases [cytosol] (Sus scrofa)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Sus scrofa)
        
        CUL5-box protein [cytosol] (Sus scrofa)
        
        WSB1 [cytosol] (Sus scrofa)
      - CRL E3 ubiquitin ligases [cytosol] (Sus scrofa)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Sus scrofa)
        
        CUL5-box protein [cytosol] (Sus scrofa)
        
        WSB1 [cytosol] (Sus scrofa)
    - COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes (Sus scrofa)
      - CRL E3 ubiquitin ligase:CAND1 [cytosol] (Sus scrofa)
        
        CRL E3 ubiquitin ligases [cytosol] (Sus scrofa)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Sus scrofa)
        
        CUL5-box protein [cytosol] (Sus scrofa)
        
        WSB1 [cytosol] (Sus scrofa)
      - CRL E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        CRL5 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Sus scrofa)
        
        CUL5-box protein [cytosol] (Sus scrofa)
        
        WSB1 [cytosol] (Sus scrofa)
    - COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Sus scrofa)
      - CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Sus scrofa)
        
        CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Sus scrofa)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Sus scrofa)
        
        CUL5-box protein [cytosol] (Sus scrofa)
        
        WSB1 [cytosol] (Sus scrofa)
      - NEDD8 CRL E3 ubiquitin ligases:COMMDs:CCDC22:DCUN1Ds [cytosol] (Sus scrofa)
        
        NEDD8-CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Sus scrofa)
        
        NEDD8-CRL5 E3 ligase [cytosol] (Sus scrofa)
        
        CUL5-box protein [cytosol] (Sus scrofa)
        
        WSB1 [cytosol] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A286ZUC3

Gene Names

WSB1

Reference Genes

ENSEMBL:ENSSSCG00000017752.5

ENSEMBL:ENSSSCG00005030879.1 WSB1

Reference Transcript

RefSeq:XM_003131753.4 WSB1

Other Identifiers

100525660

GO:0000209

GO:0003824

GO:0005515

GO:0005737

GO:0016567

GO:0016740

GO:0023052

GO:0035556

GO:0036211

GO:0044314

GO:0061630

GO:0140096

GO:0140454

Ssc.977.1.A1_at

Participates

as a member of

Inferred From

WSB1 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_003131801.1

OpenTargets

ENSG00000109046

Ensembl

ENSSSCT00000060207, ENSSSCP00000035091, ENSSSCG00000017752

VGNC

94981