Reactome | KLC2 [cytosol]

KLC2 [cytosol]

Stable Identifier

R-SSC-983191

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

cytosol

Synonyms

KLC2, A0A287A561

Locations in the PathwayBrowser

Expand all

Signal Transduction (Sus scrofa)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Sus scrofa)
  - Signaling by Rho GTPases (Sus scrofa)
    - RHO GTPase Effectors (Sus scrofa)
      - RHO GTPases activate KTN1 (Sus scrofa)
        
        KTN1 binds Kinesin-1 (Sus scrofa)
        
        Kinesin-1 [cytosol] (Sus scrofa)
        
        KLC1,KLC2,KLC3,KLC4 [cytosol] (Sus scrofa)
        
        KLC2 [cytosol] (Sus scrofa)
        
        RHOA,RHOG,RAC1,CDC42:GTP:KTN1:Kinesin-1 [endoplasmic reticulum membrane] (Sus scrofa)
        
        Kinesin-1 [cytosol] (Sus scrofa)
        
        KLC1,KLC2,KLC3,KLC4 [cytosol] (Sus scrofa)
        
        KLC2 [cytosol] (Sus scrofa)

Vesicle-mediated transport (Sus scrofa)

- Membrane Trafficking (Sus scrofa)
  - Intra-Golgi and retrograde Golgi-to-ER traffic (Sus scrofa)
    - Golgi-to-ER retrograde transport (Sus scrofa)
      - COPI-dependent Golgi-to-ER retrograde traffic (Sus scrofa)
        
        Retrograde COPI vesicles bind kinesin and microtubules (Sus scrofa)
        
        Kinesins:microtubule [cytosol] (Sus scrofa)
        
        Kinesins [cytosol] (Sus scrofa)
        
        Kinesin-1 [cytosol] (Sus scrofa)
        
        KLC1,KLC2,KLC3,KLC4 [cytosol] (Sus scrofa)
        
        KLC2 [cytosol] (Sus scrofa)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:kinesins:microtubules [transport vesicle] (Sus scrofa)
        
        Kinesins:microtubule [cytosol] (Sus scrofa)
        
        Kinesins [cytosol] (Sus scrofa)
        
        Kinesin-1 [cytosol] (Sus scrofa)
        
        KLC1,KLC2,KLC3,KLC4 [cytosol] (Sus scrofa)
        
        KLC2 [cytosol] (Sus scrofa)
        
        Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs (Sus scrofa)
        
        Kinesins:microtubule [cytosol] (Sus scrofa)
        
        Kinesins [cytosol] (Sus scrofa)
        
        Kinesin-1 [cytosol] (Sus scrofa)
        
        KLC1,KLC2,KLC3,KLC4 [cytosol] (Sus scrofa)
        
        KLC2 [cytosol] (Sus scrofa)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:kinesins:microtubules [transport vesicle] (Sus scrofa)
        
        Kinesins:microtubule [cytosol] (Sus scrofa)
        
        Kinesins [cytosol] (Sus scrofa)
        
        Kinesin-1 [cytosol] (Sus scrofa)
        
        KLC1,KLC2,KLC3,KLC4 [cytosol] (Sus scrofa)
        
        KLC2 [cytosol] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A287A561

Gene Names

KLC2

Reference Genes

ENSEMBL:ENSSSCG00000012955.5

Other Identifiers

100521540

GO:0005515

GO:0005634

GO:0005654

GO:0005739

GO:0005829

GO:0005856

GO:0005871

GO:0005874

GO:0005886

GO:0032418

GO:0032991

GO:0043226

Participates

as a member of

KLC1,KLC2,KLC3,KLC4 [cytosol] (Sus scrofa)

Inferred From

KLC2 [cytosol] (Homo sapiens)

Cross References

OpenTargets

ENSG00000174996

Ensembl

ENSSSCP00000039005, ENSSSCG00000012955, ENSSSCT00000056180

VGNC

89486