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p-Y185,Y187 MAPK1 dimer [nucleoplasm]
Stable Identifier
R-XTR-109856
Type
Complex
Species
Xenopus tropicalis
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Xenopus tropicalis)
Cellular responses to stress (Xenopus tropicalis)
Cellular Senescence (Xenopus tropicalis)
Oncogene Induced Senescence (Xenopus tropicalis)
MAPKs phosphorylate ETS1 and ETS2 (Xenopus tropicalis)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)
Oxidative Stress Induced Senescence (Xenopus tropicalis)
c-FOS activation by phospho ERK1/2 (Xenopus tropicalis)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)
Senescence-Associated Secretory Phenotype (SASP) (Xenopus tropicalis)
ERK1/2/5 activate RSK1/2/3 (Xenopus tropicalis)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)
Immune System (Xenopus tropicalis)
Cytokine Signaling in Immune system (Xenopus tropicalis)
Signaling by Interleukins (Xenopus tropicalis)
Interleukin-17 signaling (Xenopus tropicalis)
MAP kinase activation (Xenopus tropicalis)
MAPK targets/ Nuclear events mediated by MAP kinases (Xenopus tropicalis)
Activation of the AP-1 family of transcription factors (Xenopus tropicalis)
c-FOS activation by phospho ERK1/2 (Xenopus tropicalis)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)
ERK/MAPK targets (Xenopus tropicalis)
ERK1/2/5 activate RSK1/2/3 (Xenopus tropicalis)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)
ERKs are inactivated (Xenopus tropicalis)
ERKs are inactivated by dual-specific phosphatases (DUSPs) (Xenopus tropicalis)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)
Innate Immune System (Xenopus tropicalis)
Fc epsilon receptor (FCERI) signaling (Xenopus tropicalis)
FCERI mediated MAPK activation (Xenopus tropicalis)
c-FOS activation by phospho ERK1/2 (Xenopus tropicalis)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)
Toll-like Receptor Cascades (Xenopus tropicalis)
Toll Like Receptor 10 (TLR10) Cascade (Xenopus tropicalis)
MyD88 cascade initiated on plasma membrane (Xenopus tropicalis)
MAP kinase activation (Xenopus tropicalis)
MAPK targets/ Nuclear events mediated by MAP kinases (Xenopus tropicalis)
Activation of the AP-1 family of transcription factors (Xenopus tropicalis)
c-FOS activation by phospho ERK1/2 (Xenopus tropicalis)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)
ERK/MAPK targets (Xenopus tropicalis)
ERK1/2/5 activate RSK1/2/3 (Xenopus tropicalis)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)
ERKs are inactivated (Xenopus tropicalis)
ERKs are inactivated by dual-specific phosphatases (DUSPs) (Xenopus tropicalis)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)
Toll Like Receptor 2 (TLR2) Cascade (Xenopus tropicalis)
Toll Like Receptor TLR1:TLR2 Cascade (Xenopus tropicalis)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Xenopus tropicalis)
MAP kinase activation (Xenopus tropicalis)
MAPK targets/ Nuclear events mediated by MAP kinases (Xenopus tropicalis)
Activation of the AP-1 family of transcription factors (Xenopus tropicalis)
c-FOS activation by phospho ERK1/2 (Xenopus tropicalis)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)
ERK/MAPK targets (Xenopus tropicalis)
ERK1/2/5 activate RSK1/2/3 (Xenopus tropicalis)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)
ERKs are inactivated (Xenopus tropicalis)
ERKs are inactivated by dual-specific phosphatases (DUSPs) (Xenopus tropicalis)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)
Toll Like Receptor TLR6:TLR2 Cascade (Xenopus tropicalis)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Xenopus tropicalis)
MAP kinase activation (Xenopus tropicalis)
MAPK targets/ Nuclear events mediated by MAP kinases (Xenopus tropicalis)
Activation of the AP-1 family of transcription factors (Xenopus tropicalis)
c-FOS activation by phospho ERK1/2 (Xenopus tropicalis)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)
ERK/MAPK targets (Xenopus tropicalis)
ERK1/2/5 activate RSK1/2/3 (Xenopus tropicalis)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)
ERKs are inactivated (Xenopus tropicalis)
ERKs are inactivated by dual-specific phosphatases (DUSPs) (Xenopus tropicalis)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)
Toll Like Receptor 3 (TLR3) Cascade (Xenopus tropicalis)
MAP kinase activation (Xenopus tropicalis)
MAPK targets/ Nuclear events mediated by MAP kinases (Xenopus tropicalis)
Activation of the AP-1 family of transcription factors (Xenopus tropicalis)
c-FOS activation by phospho ERK1/2 (Xenopus tropicalis)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)
ERK/MAPK targets (Xenopus tropicalis)
ERK1/2/5 activate RSK1/2/3 (Xenopus tropicalis)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)
ERKs are inactivated (Xenopus tropicalis)
ERKs are inactivated by dual-specific phosphatases (DUSPs) (Xenopus tropicalis)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)
Toll Like Receptor 4 (TLR4) Cascade (Xenopus tropicalis)
MyD88-independent TLR4 cascade (Xenopus tropicalis)
TRIF (TICAM1)-mediated TLR4 signaling (Xenopus tropicalis)
MAP kinase activation (Xenopus tropicalis)
MAPK targets/ Nuclear events mediated by MAP kinases (Xenopus tropicalis)
Activation of the AP-1 family of transcription factors (Xenopus tropicalis)
c-FOS activation by phospho ERK1/2 (Xenopus tropicalis)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)
ERK/MAPK targets (Xenopus tropicalis)
ERK1/2/5 activate RSK1/2/3 (Xenopus tropicalis)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)
ERKs are inactivated (Xenopus tropicalis)
ERKs are inactivated by dual-specific phosphatases (DUSPs) (Xenopus tropicalis)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Xenopus tropicalis)
MAP kinase activation (Xenopus tropicalis)
MAPK targets/ Nuclear events mediated by MAP kinases (Xenopus tropicalis)
Activation of the AP-1 family of transcription factors (Xenopus tropicalis)
c-FOS activation by phospho ERK1/2 (Xenopus tropicalis)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)
ERK/MAPK targets (Xenopus tropicalis)
ERK1/2/5 activate RSK1/2/3 (Xenopus tropicalis)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)
ERKs are inactivated (Xenopus tropicalis)
ERKs are inactivated by dual-specific phosphatases (DUSPs) (Xenopus tropicalis)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)
Toll Like Receptor 5 (TLR5) Cascade (Xenopus tropicalis)
MyD88 cascade initiated on plasma membrane (Xenopus tropicalis)
MAP kinase activation (Xenopus tropicalis)
MAPK targets/ Nuclear events mediated by MAP kinases (Xenopus tropicalis)
Activation of the AP-1 family of transcription factors (Xenopus tropicalis)
c-FOS activation by phospho ERK1/2 (Xenopus tropicalis)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)
ERK/MAPK targets (Xenopus tropicalis)
ERK1/2/5 activate RSK1/2/3 (Xenopus tropicalis)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)
ERKs are inactivated (Xenopus tropicalis)
ERKs are inactivated by dual-specific phosphatases (DUSPs) (Xenopus tropicalis)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Xenopus tropicalis)
MyD88 dependent cascade initiated on endosome (Xenopus tropicalis)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Xenopus tropicalis)
MAP kinase activation (Xenopus tropicalis)
MAPK targets/ Nuclear events mediated by MAP kinases (Xenopus tropicalis)
Activation of the AP-1 family of transcription factors (Xenopus tropicalis)
c-FOS activation by phospho ERK1/2 (Xenopus tropicalis)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)
ERK/MAPK targets (Xenopus tropicalis)
ERK1/2/5 activate RSK1/2/3 (Xenopus tropicalis)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)
ERKs are inactivated (Xenopus tropicalis)
ERKs are inactivated by dual-specific phosphatases (DUSPs) (Xenopus tropicalis)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)
Toll Like Receptor 9 (TLR9) Cascade (Xenopus tropicalis)
MyD88 dependent cascade initiated on endosome (Xenopus tropicalis)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Xenopus tropicalis)
MAP kinase activation (Xenopus tropicalis)
MAPK targets/ Nuclear events mediated by MAP kinases (Xenopus tropicalis)
Activation of the AP-1 family of transcription factors (Xenopus tropicalis)
c-FOS activation by phospho ERK1/2 (Xenopus tropicalis)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)
ERK/MAPK targets (Xenopus tropicalis)
ERK1/2/5 activate RSK1/2/3 (Xenopus tropicalis)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)
ERKs are inactivated (Xenopus tropicalis)
ERKs are inactivated by dual-specific phosphatases (DUSPs) (Xenopus tropicalis)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)
Signal Transduction (Xenopus tropicalis)
MAPK family signaling cascades (Xenopus tropicalis)
MAPK1/MAPK3 signaling (Xenopus tropicalis)
RAF-independent MAPK1/3 activation (Xenopus tropicalis)
Nuclear DUSPs dephosphorylate MAPKs (Xenopus tropicalis)
p-T,Y MAPK monomers and dimers [nucleoplasm] (Xenopus tropicalis)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)
Phosphorylated MAPKs translocate into the nucleus (Xenopus tropicalis)
p-T,Y MAPK monomers and dimers [nucleoplasm] (Xenopus tropicalis)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)
RAF/MAP kinase cascade (Xenopus tropicalis)
Negative regulation of MAPK pathway (Xenopus tropicalis)
Nuclear DUSPs dephosphorylate MAPKs (Xenopus tropicalis)
p-T,Y MAPK monomers and dimers [nucleoplasm] (Xenopus tropicalis)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)
Phosphorylated MAPKs translocate into the nucleus (Xenopus tropicalis)
p-T,Y MAPK monomers and dimers [nucleoplasm] (Xenopus tropicalis)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)
Signaling by GPCR (Xenopus tropicalis)
GPCR downstream signalling (Xenopus tropicalis)
G alpha (q) signalling events (Xenopus tropicalis)
Gastrin-CREB signalling pathway via PKC and MAPK (Xenopus tropicalis)
ERK1/2/5 activate RSK1/2/3 (Xenopus tropicalis)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)
Signaling by Nuclear Receptors (Xenopus tropicalis)
ESR-mediated signaling (Xenopus tropicalis)
Extra-nuclear estrogen signaling (Xenopus tropicalis)
Estrogen-dependent nuclear events downstream of ESR-membrane signaling (Xenopus tropicalis)
p-S10 CDKN1B translocates to the cytosol (Xenopus tropicalis)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)
Estrogen-stimulated signaling through PRKCZ (Xenopus tropicalis)
ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus (Xenopus tropicalis)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)
Signaling by Receptor Tyrosine Kinases (Xenopus tropicalis)
Signaling by NTRKs (Xenopus tropicalis)
Signaling by NTRK1 (TRKA) (Xenopus tropicalis)
Nuclear Events (kinase and transcription factor activation) (Xenopus tropicalis)
ERK/MAPK targets (Xenopus tropicalis)
ERK1/2/5 activate RSK1/2/3 (Xenopus tropicalis)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)
ERKs are inactivated (Xenopus tropicalis)
ERKs are inactivated by dual-specific phosphatases (DUSPs) (Xenopus tropicalis)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)
Signalling to ERKs (Xenopus tropicalis)
Prolonged ERK activation events (Xenopus tropicalis)
Frs2-mediated activation (Xenopus tropicalis)
p-T,Y MAPK dimers translocate to nucleus (Xenopus tropicalis)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
x 2
phospho-p-T185,Y187-MAPK1 [nucleoplasm]
(Xenopus tropicalis)
Participates
as an output of
ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus (Xenopus tropicalis)
p-T,Y MAPK dimers translocate to nucleus (Xenopus tropicalis)
as an input of
ERKs are inactivated by dual-specific phosphatases (DUSPs) (Xenopus tropicalis)
as a member of
p-T,Y MAPK monomers and dimers [nucleoplasm] (Xenopus tropicalis)
This entity regulates
Positively
p-S10 CDKN1B translocates to the cytosol
(Xenopus tropicalis)
Inferred From
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm]
(Homo sapiens)
p-T,Y MAPK dimers [nucleoplasm]
(Homo sapiens)
p-Y185,Y187 MAPK1 dimer [nucleoplasm]
(Homo sapiens)
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