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TIMP2 [extracellular region]
Stable Identifier
R-XTR-1454879
Type
Protein [EntityWithAccessionedSequence]
Species
Xenopus tropicalis
Compartment
extracellular region
Synonyms
F6VSG7
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Xenopus tropicalis)
Degradation of the extracellular matrix (Xenopus tropicalis)
Activation of Matrix Metalloproteinases (Xenopus tropicalis)
Autocatalytic activation of bound proMMP2 (Xenopus tropicalis)
MMP14:TIMP2:MMP2 intermediate form [plasma membrane] (Xenopus tropicalis)
MMP14:TIMP2 [plasma membrane] (Xenopus tropicalis)
TIMP2 [extracellular region] (Xenopus tropicalis)
MMP14:TIMP:MMP2 [plasma membrane] (Xenopus tropicalis)
MMP14:TIMP2 [plasma membrane] (Xenopus tropicalis)
TIMP2 [extracellular region] (Xenopus tropicalis)
Initial activation of proMMP2 by MMP14 (Xenopus tropicalis)
MMP14:TIMP2:MMP2 intermediate form [plasma membrane] (Xenopus tropicalis)
MMP14:TIMP2 [plasma membrane] (Xenopus tropicalis)
TIMP2 [extracellular region] (Xenopus tropicalis)
MMP14:TIMP2:proMMP2 [plasma membrane] (Xenopus tropicalis)
MMP14:TIMP2 [plasma membrane] (Xenopus tropicalis)
TIMP2 [extracellular region] (Xenopus tropicalis)
MMP14 (MT1-MMP) binds TIMP2 (Xenopus tropicalis)
MMP14:TIMP2 [plasma membrane] (Xenopus tropicalis)
TIMP2 [extracellular region] (Xenopus tropicalis)
TIMP2 [extracellular region] (Xenopus tropicalis)
MMP14:TIMP2 binds proMMP2 (Xenopus tropicalis)
MMP14:TIMP2 [plasma membrane] (Xenopus tropicalis)
TIMP2 [extracellular region] (Xenopus tropicalis)
MMP14:TIMP2:proMMP2 [plasma membrane] (Xenopus tropicalis)
MMP14:TIMP2 [plasma membrane] (Xenopus tropicalis)
TIMP2 [extracellular region] (Xenopus tropicalis)
Immune System (Xenopus tropicalis)
Innate Immune System (Xenopus tropicalis)
Neutrophil degranulation (Xenopus tropicalis)
Exocytosis of ficolin-rich granule lumen proteins (Xenopus tropicalis)
Ficolin-rich granule lumen proteins [extracellular region] (Xenopus tropicalis)
TIMP2 [extracellular region] (Xenopus tropicalis)
Exocytosis of specific granule lumen proteins (Xenopus tropicalis)
Specific granule lumen proteins [extracellular region] (Xenopus tropicalis)
TIMP2 [extracellular region] (Xenopus tropicalis)
Exocytosis of tertiary granule lumen proteins (Xenopus tropicalis)
Tertiary granule lumen proteins [extracellular region] (Xenopus tropicalis)
TIMP2 [extracellular region] (Xenopus tropicalis)
Signal Transduction (Xenopus tropicalis)
Signaling by TGFB family members (Xenopus tropicalis)
Signaling by TGFBR3 (Xenopus tropicalis)
TGFBR3 PTM regulation (Xenopus tropicalis)
TGFBR3_mem cleavage by MMPs (Xenopus tropicalis)
TIMP2 [extracellular region] (Xenopus tropicalis)
External Reference Information
External Reference
UniProt:F6VSG7
Reference Genes
BioGPS Gene:548477
ENSEMBL:ENSXETG00000020206
KEGG Gene (Xenopus tropicalis):548477
Monarch:548477
NCBI Gene:548477
Reference Transcript
RefSeq:NM_001015760.1
Other Identifiers
548477
GO:0004857
GO:0008191
GO:0030414
GO:0046872
GO:0098772
Participates
as a member of
Tertiary granule lumen proteins [extracellular region] (Xenopus tropicalis)
Specific granule lumen proteins [extracellular region] (Xenopus tropicalis)
Ficolin-rich granule lumen proteins [extracellular region] (Xenopus tropicalis)
as an input of
MMP14 (MT1-MMP) binds TIMP2 (Xenopus tropicalis)
as a component of
MMP14:TIMP2 [plasma membrane] (Xenopus tropicalis)
This entity regulates
Negatively
TGFBR3_mem cleavage by MMPs
(Xenopus tropicalis)
Other forms of this molecule
TIMP2 [tertiary granule lumen]
TIMP2 [specific granule lumen]
TIMP2 [ficolin-1-rich granule lumen]
Inferred From
TIMP2 [extracellular region]
(Homo sapiens)
Cross References
RefSeq
NP_001015760.1
Xenbase
XB-GENE-949671
Ensembl
ENSXETG00000020206
,
ENSXETT00000043611
,
ENSXETP00000043611
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