Reactome | phospho-p-4Y-EGFR [plasma membrane]

phospho-p-4Y-EGFR [plasma membrane]

Stable Identifier

R-XTR-180287

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

plasma membrane

Synonyms

F6UFM4

Locations in the PathwayBrowser

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Signal Transduction (Xenopus tropicalis)

- Signaling by Receptor Tyrosine Kinases (Xenopus tropicalis)
  - Signaling by EGFR (Xenopus tropicalis)
    - GAB1 signalosome (Xenopus tropicalis)
      - SHP2 dephosphorylates Tyr 992 on EGFR (Xenopus tropicalis)
        
        EGF-like ligands:p-5Y-EGFR:GRB2:p-5Y-GAB1:SHP2 [plasma membrane] (Xenopus tropicalis)
        
        EGF-like ligands:Phospho-EGFR (-Y1016) dimer [plasma membrane] (Xenopus tropicalis)
        
        EGF-like ligands:Phospho-EGFR (- Y992) [plasma membrane] (Xenopus tropicalis)
        
        phospho-p-4Y-EGFR [plasma membrane] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:F6UFM4

Reference Genes

ENSEMBL:ENSXETG00000015826

KEGG:xtr:100492965

UCSC:F6UFM4

Reference Transcript

RefSeq:XM_002939914.5

Other Identifiers

100492965

GO:0000166

GO:0003824

GO:0004672

GO:0004713

GO:0004714

GO:0005524

GO:0005886

GO:0007169

GO:0010646

GO:0016020

GO:0016301

GO:0016310

GO:0016740

GO:0023051

GO:0023052

GO:0036211

GO:0038127

GO:0042127

GO:0060089

GO:0098590

GO:0140096

Participates

as a component of

EGF-like ligands:Phospho-EGFR (- Y992) [plasma membrane] (Xenopus tropicalis)

Other forms of this molecule

phospho-p-Y1016,Y1069,Y1092,Y1110,Y1197-EGFR [plasma membrane]

EGFR [plasma membrane]

phospho-p-6Y-EGFR [plasma membrane]

Inferred From

p-4Y-EGFR [plasma membrane] (Homo sapiens)

Modified Residues

Name

O4'-phospho-L-tyrosine at 1092 (in Homo sapiens)

Coordinate

1092

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Name

O4'-phospho-L-tyrosine at 1172 (in Homo sapiens)

Coordinate

1172

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Name

O4'-phospho-L-tyrosine at 1197 (in Homo sapiens)

Coordinate

1197

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Name

O4'-phospho-L-tyrosine at 1110 (in Homo sapiens)

Coordinate

1110

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

RefSeq

XP_002939960.3

ENSEMBL

ENSXETT00000034519, ENSXETP00000034519, ENSXETG00000015826

Xenbase

XB-GENE-6067152

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