Reactome | wasf2 [cytosol]

wasf2 [cytosol]

Stable Identifier

R-XTR-200972

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

cytosol

Synonyms

WASF2, F7E7Y1

Locations in the PathwayBrowser

Expand all

Immune System (Xenopus tropicalis)

- Innate Immune System (Xenopus tropicalis)
  - Fcgamma receptor (FCGR) dependent phagocytosis (Xenopus tropicalis)
    - Regulation of actin dynamics for phagocytic cup formation (Xenopus tropicalis)
      - ABL phosphorylates WAVEs (Xenopus tropicalis)
        
        WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Xenopus tropicalis)
        
        WAVE Regulatory Complex [cytosol] (Xenopus tropicalis)
        
        WAVEs [cytosol] (Xenopus tropicalis)
        
        wasf2 [cytosol] (Xenopus tropicalis)

Signal Transduction (Xenopus tropicalis)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Xenopus tropicalis)
  - Signaling by Rho GTPases (Xenopus tropicalis)
    - RHO GTPase Effectors (Xenopus tropicalis)
      - RHO GTPases Activate WASPs and WAVEs (Xenopus tropicalis)
        
        ABL phosphorylates WAVEs (Xenopus tropicalis)
        
        WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Xenopus tropicalis)
        
        WAVE Regulatory Complex [cytosol] (Xenopus tropicalis)
        
        WAVEs [cytosol] (Xenopus tropicalis)
        
        wasf2 [cytosol] (Xenopus tropicalis)
    - RHO GTPase cycle (Xenopus tropicalis)
      - RAC1 GTPase cycle (Xenopus tropicalis)
        
        RAC1 binds effectors at the plasma membrane (Xenopus tropicalis)
        
        RAC1 effectors [cytosol] (Xenopus tropicalis)
        
        WAVE Regulatory Complex [cytosol] (Xenopus tropicalis)
        
        WAVEs [cytosol] (Xenopus tropicalis)
        
        wasf2 [cytosol] (Xenopus tropicalis)
        
        RAC1:GTP:RAC1 effectors [plasma membrane] (Xenopus tropicalis)
        
        RAC1 effectors [cytosol] (Xenopus tropicalis)
        
        WAVE Regulatory Complex [cytosol] (Xenopus tropicalis)
        
        WAVEs [cytosol] (Xenopus tropicalis)
        
        wasf2 [cytosol] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:F7E7Y1

Gene Names

wasf2

Reference Genes

BioGPS Gene:100125121 wasf2

ENSEMBL:ENSXETG00000003647

KEGG:xtr:100125121 wasf2

Monarch:100125121 wasf2

NCBI Gene:100125121 wasf2

UCSC:F7E7Y1 wasf2

Reference Transcript

Other Identifiers

100125121

GO:0003779

GO:0005737

GO:0005856

GO:0007010

GO:0008092

GO:0030036

GO:0043226

Participates

as a member of

WAVEs [cytosol] (Xenopus tropicalis)

Other forms of this molecule

phospho-wasf2 [cytosol]

Inferred From

WASF2 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001096496.1, XP_031751488.1

ENSEMBL

ENSXETP00000044664, ENSXETT00000044664

Xenbase

XB-GENE-5953840

Cite Us!