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BMP2 dimer [extracellular region]
Stable Identifier
R-XTR-201463
Type
Complex
Species
Xenopus tropicalis
Compartment
extracellular region
Locations in the PathwayBrowser
Expand all
Signal Transduction (Xenopus tropicalis)
Signaling by TGFB family members (Xenopus tropicalis)
Signaling by BMP (Xenopus tropicalis)
Activated type I receptor phosphorylates R-Smad1/5/8 directly (Xenopus tropicalis)
BMP:p-BMPR:Endofin:SMAD1/5/8 [early endosome membrane] (Xenopus tropicalis)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Xenopus tropicalis)
BMP2 dimer [extracellular region] (Xenopus tropicalis)
BMP:p-BMPR:Endofin:p-2S-SMAD1/5/8 [early endosome membrane] (Xenopus tropicalis)
BMP2 dimer [extracellular region] (Xenopus tropicalis)
An anchoring protein, Endofin, recruits R-Smad1/5/8 (Xenopus tropicalis)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Xenopus tropicalis)
BMP2 dimer [extracellular region] (Xenopus tropicalis)
BMP:p-BMPR:Endofin:SMAD1/5/8 [early endosome membrane] (Xenopus tropicalis)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Xenopus tropicalis)
BMP2 dimer [extracellular region] (Xenopus tropicalis)
BMP2 binds to the receptor complex (Xenopus tropicalis)
BMP2 dimer [extracellular region] (Xenopus tropicalis)
BMP:BMPRII:BMPRI [plasma membrane] (Xenopus tropicalis)
BMP2 dimer [extracellular region] (Xenopus tropicalis)
Phospho-R-Smad1/5/8 dissociates from the receptor complex (Xenopus tropicalis)
BMP:p-BMPR:Endofin [early endosome membrane] (Xenopus tropicalis)
BMP2 dimer [extracellular region] (Xenopus tropicalis)
BMP:p-BMPR:Endofin:p-2S-SMAD1/5/8 [early endosome membrane] (Xenopus tropicalis)
BMP2 dimer [extracellular region] (Xenopus tropicalis)
The ligand trap binds the ligand BMP2, blocking BMP signalling (Xenopus tropicalis)
BMP2 dimer [extracellular region] (Xenopus tropicalis)
Ligand Trap:BMP2 [extracellular region] (Xenopus tropicalis)
BMP2 dimer [extracellular region] (Xenopus tropicalis)
Type II receptor phosphorylates type I receptor (Xenopus tropicalis)
BMP:BMPRII:BMPRI [plasma membrane] (Xenopus tropicalis)
BMP2 dimer [extracellular region] (Xenopus tropicalis)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Xenopus tropicalis)
BMP2 dimer [extracellular region] (Xenopus tropicalis)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
x 2
bmp2 [extracellular region]
(Xenopus tropicalis)
Participates
as an input of
The ligand trap binds the ligand BMP2, blocking BMP signalling (Xenopus tropicalis)
BMP2 binds to the receptor complex (Xenopus tropicalis)
as a component of
Ligand Trap:BMP2 [extracellular region] (Xenopus tropicalis)
BMP:BMPRII:BMPRI [plasma membrane] (Xenopus tropicalis)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Xenopus tropicalis)
BMP:p-BMPR:Endofin [early endosome membrane] (Xenopus tropicalis)
BMP:p-BMPR:Endofin:p-2S-SMAD1/5/8 [early endosome membrane] (Xenopus tropicalis)
Inferred From
BMP2 dimer [extracellular region]
(Homo sapiens)
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