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phospho-p-S621-RAF1 [cytosol]
Stable Identifier
R-XTR-206028
Type
Protein [EntityWithAccessionedSequence]
Species
Xenopus tropicalis
Compartment
cytosol
Synonyms
F6RZI1
Locations in the PathwayBrowser
Expand all
Immune System (Xenopus tropicalis)
Cytokine Signaling in Immune system (Xenopus tropicalis)
FLT3 Signaling (Xenopus tropicalis)
RAF/MAP kinase cascade (Xenopus tropicalis)
MAP2K and MAPK activation (Xenopus tropicalis)
RAF phosphorylates MAP2K dimer (Xenopus tropicalis)
p21RAS:GTP:homo/heterodimerized RAF complex:RAF dimer inhibitors [plasma membrane] (Xenopus tropicalis)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Xenopus tropicalis)
dephosphorylated "receiver" RAF/KSR1 [cytosol] (Xenopus tropicalis)
phospho-p-S621-RAF1 [cytosol] (Xenopus tropicalis)
RAF activation (Xenopus tropicalis)
PP2A dephosphorylates inactive RAFs (Xenopus tropicalis)
dephosphorylated inactive RAFS:YWHAB dimer [cytosol] (Xenopus tropicalis)
dephosphorylated inactive RAFs [cytosol] (Xenopus tropicalis)
phospho-p-S621-RAF1 [cytosol] (Xenopus tropicalis)
Phosphorylation of RAF (Xenopus tropicalis)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Xenopus tropicalis)
dephosphorylated "receiver" RAF/KSR1 [cytosol] (Xenopus tropicalis)
phospho-p-S621-RAF1 [cytosol] (Xenopus tropicalis)
RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers (Xenopus tropicalis)
dephosphorylated "receiver" RAF/KSR1 [cytosol] (Xenopus tropicalis)
phospho-p-S621-RAF1 [cytosol] (Xenopus tropicalis)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Xenopus tropicalis)
dephosphorylated "receiver" RAF/KSR1 [cytosol] (Xenopus tropicalis)
phospho-p-S621-RAF1 [cytosol] (Xenopus tropicalis)
YWHAB dimer dissociates from dephosphorylated RAF (Xenopus tropicalis)
dephosphorylated inactive RAFS:YWHAB dimer [cytosol] (Xenopus tropicalis)
dephosphorylated inactive RAFs [cytosol] (Xenopus tropicalis)
phospho-p-S621-RAF1 [cytosol] (Xenopus tropicalis)
dephosphorylated inactive RAFs [cytosol] (Xenopus tropicalis)
phospho-p-S621-RAF1 [cytosol] (Xenopus tropicalis)
Signal Transduction (Xenopus tropicalis)
MAPK family signaling cascades (Xenopus tropicalis)
MAPK1/MAPK3 signaling (Xenopus tropicalis)
RAF/MAP kinase cascade (Xenopus tropicalis)
MAP2K and MAPK activation (Xenopus tropicalis)
RAF phosphorylates MAP2K dimer (Xenopus tropicalis)
p21RAS:GTP:homo/heterodimerized RAF complex:RAF dimer inhibitors [plasma membrane] (Xenopus tropicalis)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Xenopus tropicalis)
dephosphorylated "receiver" RAF/KSR1 [cytosol] (Xenopus tropicalis)
phospho-p-S621-RAF1 [cytosol] (Xenopus tropicalis)
RAF activation (Xenopus tropicalis)
PP2A dephosphorylates inactive RAFs (Xenopus tropicalis)
dephosphorylated inactive RAFS:YWHAB dimer [cytosol] (Xenopus tropicalis)
dephosphorylated inactive RAFs [cytosol] (Xenopus tropicalis)
phospho-p-S621-RAF1 [cytosol] (Xenopus tropicalis)
Phosphorylation of RAF (Xenopus tropicalis)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Xenopus tropicalis)
dephosphorylated "receiver" RAF/KSR1 [cytosol] (Xenopus tropicalis)
phospho-p-S621-RAF1 [cytosol] (Xenopus tropicalis)
RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers (Xenopus tropicalis)
dephosphorylated "receiver" RAF/KSR1 [cytosol] (Xenopus tropicalis)
phospho-p-S621-RAF1 [cytosol] (Xenopus tropicalis)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Xenopus tropicalis)
dephosphorylated "receiver" RAF/KSR1 [cytosol] (Xenopus tropicalis)
phospho-p-S621-RAF1 [cytosol] (Xenopus tropicalis)
YWHAB dimer dissociates from dephosphorylated RAF (Xenopus tropicalis)
dephosphorylated inactive RAFS:YWHAB dimer [cytosol] (Xenopus tropicalis)
dephosphorylated inactive RAFs [cytosol] (Xenopus tropicalis)
phospho-p-S621-RAF1 [cytosol] (Xenopus tropicalis)
dephosphorylated inactive RAFs [cytosol] (Xenopus tropicalis)
phospho-p-S621-RAF1 [cytosol] (Xenopus tropicalis)
External Reference Information
External Reference
UniProt:F6RZI1
Reference Genes
ENSEMBL:ENSXETG00000020163
Other Identifiers
100486469
chrm2
ENSXETG00000010324
ENSXETP00000043491
ENSXETT00000044809
EntrezGene:100486469
EntrezGene:nrk
F7A3M1
GO:0003674
GO:0004672
GO:0004674
GO:0005524
GO:0005575
GO:0005622
GO:0005623
GO:0005737
GO:0005739
GO:0005829
GO:0006464
GO:0006468
GO:0007165
GO:0008150
GO:0016301
GO:0035556
GO:0043167
GO:0043226
GO:0046872
IPR000719
IPR001180
IPR008271
IPR011009
IPR017441
limk1-210
nrk
PF00069
PF00780
SM00036
SM00220
XB-GENE-1011258
Participant Of
hasMember
dephosphorylated "receiver" RAF/KSR1 [cytosol]
dephosphorylated inactive RAFs [cytosol]
Other forms of this molecule
RAF1 [cytosol]
phospho-p-S338,Y340,Y341-RAF1 [cytosol]
phospho-p-S338-RAF1 [cytosol]
phospho-p-S259,S621-RAF1 [cytosol]
phospho-p-S621-RAF1 [plasma membrane]
phospho-hyperphosphorylated RAF1 [plasma membrane]
phospho-p-Y341,T491,S494,S621 RAF1 [plasma membrane]
phospho-p-S338,Y341,T491,S494,S621 RAF1 [plasma membrane]
phospho-p-S338,Y341,T491,S494,S621 RAF1 [cytosol]
Inferred From
p-S621-RAF1 [cytosol] (Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 621 (in Homo sapiens)
Coordinate
621
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
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