Reactome | fbxo32 [cytosol]

fbxo32 [cytosol]

Stable Identifier

R-XTR-264453

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

cytosol

Synonyms

FBXO32, F6ZJN6

Locations in the PathwayBrowser

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Immune System (Xenopus tropicalis)

- Adaptive Immune System (Xenopus tropicalis)
  - Class I MHC mediated antigen processing & presentation (Xenopus tropicalis)
    - Antigen processing: Ubiquitination & Proteasome degradation (Xenopus tropicalis)
      - Interaction of E3 with substrate and E2-Ub complex (Xenopus tropicalis)
        
        Ag-substrate:E3:E2:Ub [cytosol] (Xenopus tropicalis)
        
        E3 ligases in proteasomal degradation [cytosol] (Xenopus tropicalis)
        
        SCF E3 ubiquitin ligase [cytosol] (Xenopus tropicalis)
        
        F-box protein [cytosol] (Xenopus tropicalis)
        
        fbxo32 [cytosol] (Xenopus tropicalis)
        
        E3 ligases in proteasomal degradation [cytosol] (Xenopus tropicalis)
        
        SCF E3 ubiquitin ligase [cytosol] (Xenopus tropicalis)
        
        F-box protein [cytosol] (Xenopus tropicalis)
        
        fbxo32 [cytosol] (Xenopus tropicalis)
      - Polyubiquitination of substrate (Xenopus tropicalis)
        
        E3 ligases in proteasomal degradation [cytosol] (Xenopus tropicalis)
        
        SCF E3 ubiquitin ligase [cytosol] (Xenopus tropicalis)
        
        F-box protein [cytosol] (Xenopus tropicalis)
        
        fbxo32 [cytosol] (Xenopus tropicalis)
        
        E3:K48-polyubiquitinated substrate [cytosol] (Xenopus tropicalis)
        
        E3 ligases in proteasomal degradation [cytosol] (Xenopus tropicalis)
        
        SCF E3 ubiquitin ligase [cytosol] (Xenopus tropicalis)
        
        F-box protein [cytosol] (Xenopus tropicalis)
        
        fbxo32 [cytosol] (Xenopus tropicalis)
        
        E3:Ub:substrate [cytosol] (Xenopus tropicalis)
        
        E3 ligases in proteasomal degradation [cytosol] (Xenopus tropicalis)
        
        SCF E3 ubiquitin ligase [cytosol] (Xenopus tropicalis)
        
        F-box protein [cytosol] (Xenopus tropicalis)
        
        fbxo32 [cytosol] (Xenopus tropicalis)
      - Release of E3 from polyubiquitinated substrate (Xenopus tropicalis)
        
        E3 ligases in proteasomal degradation [cytosol] (Xenopus tropicalis)
        
        SCF E3 ubiquitin ligase [cytosol] (Xenopus tropicalis)
        
        F-box protein [cytosol] (Xenopus tropicalis)
        
        fbxo32 [cytosol] (Xenopus tropicalis)
        
        E3:K48-polyubiquitinated substrate [cytosol] (Xenopus tropicalis)
        
        E3 ligases in proteasomal degradation [cytosol] (Xenopus tropicalis)
        
        SCF E3 ubiquitin ligase [cytosol] (Xenopus tropicalis)
        
        F-box protein [cytosol] (Xenopus tropicalis)
        
        fbxo32 [cytosol] (Xenopus tropicalis)
      - Transfer of Ub from E2 to substrate and release of E2 (Xenopus tropicalis)
        
        Ag-substrate:E3:E2:Ub [cytosol] (Xenopus tropicalis)
        
        E3 ligases in proteasomal degradation [cytosol] (Xenopus tropicalis)
        
        SCF E3 ubiquitin ligase [cytosol] (Xenopus tropicalis)
        
        F-box protein [cytosol] (Xenopus tropicalis)
        
        fbxo32 [cytosol] (Xenopus tropicalis)
        
        E3 ligases in proteasomal degradation [cytosol] (Xenopus tropicalis)
        
        SCF E3 ubiquitin ligase [cytosol] (Xenopus tropicalis)
        
        F-box protein [cytosol] (Xenopus tropicalis)
        
        fbxo32 [cytosol] (Xenopus tropicalis)
        
        E3:Ub:substrate [cytosol] (Xenopus tropicalis)
        
        E3 ligases in proteasomal degradation [cytosol] (Xenopus tropicalis)
        
        SCF E3 ubiquitin ligase [cytosol] (Xenopus tropicalis)
        
        F-box protein [cytosol] (Xenopus tropicalis)
        
        fbxo32 [cytosol] (Xenopus tropicalis)

Metabolism of proteins (Xenopus tropicalis)

- Post-translational protein modification (Xenopus tropicalis)
  - Neddylation (Xenopus tropicalis)
    - AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex (Xenopus tropicalis)
      - CRL1 E3 ubiquitin ligase complex:MyrG-DCUN1D3 [plasma membrane] (Xenopus tropicalis)
        
        CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Xenopus tropicalis)
        
        SCF E3 ubiquitin ligase [cytosol] (Xenopus tropicalis)
        
        F-box protein [cytosol] (Xenopus tropicalis)
        
        fbxo32 [cytosol] (Xenopus tropicalis)
      - NEDD8-AcM-UBE2M:CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Xenopus tropicalis)
        
        CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Xenopus tropicalis)
        
        SCF E3 ubiquitin ligase [cytosol] (Xenopus tropicalis)
        
        F-box protein [cytosol] (Xenopus tropicalis)
        
        fbxo32 [cytosol] (Xenopus tropicalis)
      - NEDD8-CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Xenopus tropicalis)
        
        NEDD8-CRL1 E3 ligase complex [cytosol] (Xenopus tropicalis)
        
        F-box protein [cytosol] (Xenopus tropicalis)
        
        fbxo32 [cytosol] (Xenopus tropicalis)
    - CAND1 binds cytosolic CRL E3 ubiquitin ligases (Xenopus tropicalis)
      - CRL E3 ubiquitin ligase:CAND1 [cytosol] (Xenopus tropicalis)
        
        CRL E3 ubiquitin ligases [cytosol] (Xenopus tropicalis)
        
        SCF E3 ubiquitin ligase [cytosol] (Xenopus tropicalis)
        
        F-box protein [cytosol] (Xenopus tropicalis)
        
        fbxo32 [cytosol] (Xenopus tropicalis)
      - CRL E3 ubiquitin ligases [cytosol] (Xenopus tropicalis)
        
        SCF E3 ubiquitin ligase [cytosol] (Xenopus tropicalis)
        
        F-box protein [cytosol] (Xenopus tropicalis)
        
        fbxo32 [cytosol] (Xenopus tropicalis)
    - COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes (Xenopus tropicalis)
      - CRL E3 ubiquitin ligase:CAND1 [cytosol] (Xenopus tropicalis)
        
        CRL E3 ubiquitin ligases [cytosol] (Xenopus tropicalis)
        
        SCF E3 ubiquitin ligase [cytosol] (Xenopus tropicalis)
        
        F-box protein [cytosol] (Xenopus tropicalis)
        
        fbxo32 [cytosol] (Xenopus tropicalis)
      - CRL E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Xenopus tropicalis)
        
        CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Xenopus tropicalis)
        
        SCF E3 ubiquitin ligase [cytosol] (Xenopus tropicalis)
        
        F-box protein [cytosol] (Xenopus tropicalis)
        
        fbxo32 [cytosol] (Xenopus tropicalis)
    - COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Xenopus tropicalis)
      - CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Xenopus tropicalis)
        
        CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Xenopus tropicalis)
        
        SCF E3 ubiquitin ligase [cytosol] (Xenopus tropicalis)
        
        F-box protein [cytosol] (Xenopus tropicalis)
        
        fbxo32 [cytosol] (Xenopus tropicalis)
      - NEDD8 CRL E3 ubiquitin ligases:COMMDs:CCDC22:DCUN1Ds [cytosol] (Xenopus tropicalis)
        
        NEDD8-CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Xenopus tropicalis)
        
        NEDD8-CRL1 E3 ligase complex [cytosol] (Xenopus tropicalis)
        
        F-box protein [cytosol] (Xenopus tropicalis)
        
        fbxo32 [cytosol] (Xenopus tropicalis)
    - MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex (Xenopus tropicalis)
      - CRL1 E3 ubiquitin ligase complex:MyrG-DCUN1D3 [plasma membrane] (Xenopus tropicalis)
        
        CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Xenopus tropicalis)
        
        SCF E3 ubiquitin ligase [cytosol] (Xenopus tropicalis)
        
        F-box protein [cytosol] (Xenopus tropicalis)
        
        fbxo32 [cytosol] (Xenopus tropicalis)
      - CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Xenopus tropicalis)
        
        SCF E3 ubiquitin ligase [cytosol] (Xenopus tropicalis)
        
        F-box protein [cytosol] (Xenopus tropicalis)
        
        fbxo32 [cytosol] (Xenopus tropicalis)
    - NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex (Xenopus tropicalis)
      - CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Xenopus tropicalis)
        
        SCF E3 ubiquitin ligase [cytosol] (Xenopus tropicalis)
        
        F-box protein [cytosol] (Xenopus tropicalis)
        
        fbxo32 [cytosol] (Xenopus tropicalis)
      - NEDD8-AcM-UBE2M:CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Xenopus tropicalis)
        
        CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Xenopus tropicalis)
        
        SCF E3 ubiquitin ligase [cytosol] (Xenopus tropicalis)
        
        F-box protein [cytosol] (Xenopus tropicalis)
        
        fbxo32 [cytosol] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:F6ZJN6

Gene Names

fbxo32

Reference Genes

ENSEMBL:ENSXETG00000023228

Other Identifiers

100496585

GO:0003013

GO:0003674

GO:0003677

GO:0003700

GO:0004879

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005737

GO:0006355

GO:0006464

GO:0006914

GO:0007165

GO:0008150

GO:0008270

GO:0008345

GO:0009056

GO:0009058

GO:0016567

GO:0030522

GO:0034641

GO:0042025

GO:0042592

GO:0043167

GO:0043226

GO:0043565

GO:0046716

GO:0046872

GO:0048856

GO:0055008

GO:0060047

GO:0060415

Participant Of

hasMember

F-box protein [cytosol]

Inferred From

FBXO32 [cytosol] (Homo sapiens)

Cross References

Ensembl

ENSXETP00000050202, ENSXETG00000023228, ENSXETT00000050202

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