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ctnnb1 [nucleoplasm]
Stable Identifier
R-XTR-3451168
Type
Protein [EntityWithAccessionedSequence]
Species
Xenopus tropicalis
Compartment
nucleoplasm
Synonyms
CTNNB1, Q28GC2
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Xenopus tropicalis)
RNA Polymerase II Transcription (Xenopus tropicalis)
Generic Transcription Pathway (Xenopus tropicalis)
Transcriptional Regulation by VENTX (Xenopus tropicalis)
VENTX disrupts binding of CTNNB1 (beta-catenin) to TCF4 or LEF1 (Xenopus tropicalis)
CTNNB1:TCF7L2,LEF1:CCND1 Gene [nucleoplasm] (Xenopus tropicalis)
TCF/LEF:CTNNB1 [nucleoplasm] (Xenopus tropicalis)
ctnnb1 [nucleoplasm] (Xenopus tropicalis)
ctnnb1 [nucleoplasm] (Xenopus tropicalis)
Transcriptional regulation by RUNX3 (Xenopus tropicalis)
RUNX3 regulates WNT signaling (Xenopus tropicalis)
RUNX3 binds CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) (Xenopus tropicalis)
RUNX3:CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) [nucleoplasm] (Xenopus tropicalis)
TCF/LEF:CTNNB1 [nucleoplasm] (Xenopus tropicalis)
ctnnb1 [nucleoplasm] (Xenopus tropicalis)
TCF/LEF:CTNNB1 [nucleoplasm] (Xenopus tropicalis)
ctnnb1 [nucleoplasm] (Xenopus tropicalis)
Signal Transduction (Xenopus tropicalis)
Signaling by WNT (Xenopus tropicalis)
Beta-catenin independent WNT signaling (Xenopus tropicalis)
Ca2+ pathway (Xenopus tropicalis)
NLK phosphorylates TCF/LEF (Xenopus tropicalis)
TCF/LEF:CTNNB1 [nucleoplasm] (Xenopus tropicalis)
ctnnb1 [nucleoplasm] (Xenopus tropicalis)
p-TCF/LEF:CTNNB1 [nucleoplasm] (Xenopus tropicalis)
ctnnb1 [nucleoplasm] (Xenopus tropicalis)
TCF dependent signaling in response to WNT (Xenopus tropicalis)
Beta-catenin translocates to the nucleus (Xenopus tropicalis)
ctnnb1 [nucleoplasm] (Xenopus tropicalis)
Deactivation of the beta-catenin transactivating complex (Xenopus tropicalis)
AKT phosphorylates CBY1 (Xenopus tropicalis)
CBY1:CTNNB1 [nucleoplasm] (Xenopus tropicalis)
ctnnb1 [nucleoplasm] (Xenopus tropicalis)
pS20-CBY1:CTNNB1 [nucleoplasm] (Xenopus tropicalis)
ctnnb1 [nucleoplasm] (Xenopus tropicalis)
Beta-catenin binds SOX proteins (Xenopus tropicalis)
CTNNB1:SRY,SOX2,SOX3,SOX4,SOX6,SOX7,SOX9,SOX17 [nucleoplasm] (Xenopus tropicalis)
ctnnb1 [nucleoplasm] (Xenopus tropicalis)
ctnnb1 [nucleoplasm] (Xenopus tropicalis)
CBY1 binds beta-catenin (Xenopus tropicalis)
CBY1:CTNNB1 [nucleoplasm] (Xenopus tropicalis)
ctnnb1 [nucleoplasm] (Xenopus tropicalis)
ctnnb1 [nucleoplasm] (Xenopus tropicalis)
CHD8 binds beta-catenin to negatively regulate WNT-dependent gene expression (Xenopus tropicalis)
CTNNB1:CHD8 [nucleoplasm] (Xenopus tropicalis)
ctnnb1 [nucleoplasm] (Xenopus tropicalis)
ctnnb1 [nucleoplasm] (Xenopus tropicalis)
CTNNBIP1 binds beta-catenin (Xenopus tropicalis)
CTNNBIP1:CTNNB1 [nucleoplasm] (Xenopus tropicalis)
ctnnb1 [nucleoplasm] (Xenopus tropicalis)
ctnnb1 [nucleoplasm] (Xenopus tropicalis)
TCF:Beta-catenin binds SOX proteins (Xenopus tropicalis)
TCF/LEF:CTNNB1 [nucleoplasm] (Xenopus tropicalis)
ctnnb1 [nucleoplasm] (Xenopus tropicalis)
TCF/LEF:CTNNB1:SOX4,SOX13,SOX17 [nucleoplasm] (Xenopus tropicalis)
TCF/LEF:CTNNB1 [nucleoplasm] (Xenopus tropicalis)
ctnnb1 [nucleoplasm] (Xenopus tropicalis)
XPO1 binds the beta-catenin:CBY complex (Xenopus tropicalis)
XPO1:YWHAZ:p-S20-CBY1:CTNNB1 [nucleoplasm] (Xenopus tropicalis)
YWHAZ:p-S20-CBY:CTNNB1 [nucleoplasm] (Xenopus tropicalis)
pS20-CBY1:CTNNB1 [nucleoplasm] (Xenopus tropicalis)
ctnnb1 [nucleoplasm] (Xenopus tropicalis)
YWHAZ:p-S20-CBY:CTNNB1 [nucleoplasm] (Xenopus tropicalis)
pS20-CBY1:CTNNB1 [nucleoplasm] (Xenopus tropicalis)
ctnnb1 [nucleoplasm] (Xenopus tropicalis)
YWHAZ and XPO1 mediate the nuclear export of beta-catenin (Xenopus tropicalis)
XPO1:YWHAZ:p-S20-CBY1:CTNNB1 [nucleoplasm] (Xenopus tropicalis)
YWHAZ:p-S20-CBY:CTNNB1 [nucleoplasm] (Xenopus tropicalis)
pS20-CBY1:CTNNB1 [nucleoplasm] (Xenopus tropicalis)
ctnnb1 [nucleoplasm] (Xenopus tropicalis)
YWHAZ binds p-CBY:CTNNB1 (Xenopus tropicalis)
YWHAZ:p-S20-CBY:CTNNB1 [nucleoplasm] (Xenopus tropicalis)
pS20-CBY1:CTNNB1 [nucleoplasm] (Xenopus tropicalis)
ctnnb1 [nucleoplasm] (Xenopus tropicalis)
pS20-CBY1:CTNNB1 [nucleoplasm] (Xenopus tropicalis)
ctnnb1 [nucleoplasm] (Xenopus tropicalis)
Formation of the beta-catenin:TCF transactivating complex (Xenopus tropicalis)
Beta-catenin displaces TLE:HDAC1 from TCF/LEF (Xenopus tropicalis)
TCF/LEF:CTNNB1 [nucleoplasm] (Xenopus tropicalis)
ctnnb1 [nucleoplasm] (Xenopus tropicalis)
ctnnb1 [nucleoplasm] (Xenopus tropicalis)
Beta-catenin recruits CBP/p300 (Xenopus tropicalis)
TCF/LEF:CTNNB1 [nucleoplasm] (Xenopus tropicalis)
ctnnb1 [nucleoplasm] (Xenopus tropicalis)
TCF/LEF:CTNNB1:CBP/p300 [nucleoplasm] (Xenopus tropicalis)
TCF/LEF:CTNNB1 [nucleoplasm] (Xenopus tropicalis)
ctnnb1 [nucleoplasm] (Xenopus tropicalis)
Beta-catenin recruits CDC73 and LEO1 (Xenopus tropicalis)
TCF/LEF:CTNNB1 [nucleoplasm] (Xenopus tropicalis)
ctnnb1 [nucleoplasm] (Xenopus tropicalis)
TCF/LEF:CTNNB1:PAF1-like complex [nucleoplasm] (Xenopus tropicalis)
TCF/LEF:CTNNB1 [nucleoplasm] (Xenopus tropicalis)
ctnnb1 [nucleoplasm] (Xenopus tropicalis)
Beta-catenin recruits SMARCA4 (Xenopus tropicalis)
TCF/LEF:CTNNB1 [nucleoplasm] (Xenopus tropicalis)
ctnnb1 [nucleoplasm] (Xenopus tropicalis)
TCF/LEF:CTNNB1:SMARCA4:TERT [nucleoplasm] (Xenopus tropicalis)
TCF/LEF:CTNNB1 [nucleoplasm] (Xenopus tropicalis)
ctnnb1 [nucleoplasm] (Xenopus tropicalis)
Beta-catenin recruits TRRAP/KAT5 HAT components (Xenopus tropicalis)
TCF/LEF:CTNNB1 [nucleoplasm] (Xenopus tropicalis)
ctnnb1 [nucleoplasm] (Xenopus tropicalis)
TCF/LEF:CTNNB1:RUVBL1:TRRAP:KAT5 [nucleoplasm] (Xenopus tropicalis)
TCF/LEF:CTNNB1 [nucleoplasm] (Xenopus tropicalis)
ctnnb1 [nucleoplasm] (Xenopus tropicalis)
Beta-catenin:TCF associates with BCL9 and PYGO (Xenopus tropicalis)
TCF/LEF:CTNNB1 [nucleoplasm] (Xenopus tropicalis)
ctnnb1 [nucleoplasm] (Xenopus tropicalis)
TCF/LEF:CTNNB1:BCL9:PYGO [nucleoplasm] (Xenopus tropicalis)
ctnnb1 [nucleoplasm] (Xenopus tropicalis)
Recruitment of SET1 methyltransferase complex (Xenopus tropicalis)
TCF/LEF:CTNNB1:BCL9:PYGO [nucleoplasm] (Xenopus tropicalis)
ctnnb1 [nucleoplasm] (Xenopus tropicalis)
TCF/LEF:CTNNB1:BCL9:PYGO:SET1-like complex [nucleoplasm] (Xenopus tropicalis)
ctnnb1 [nucleoplasm] (Xenopus tropicalis)
SET1 complex trimethylates H3K4 at the MYC gene (Xenopus tropicalis)
TCF/LEF:CTNNB1:BCL9:PYGO:SET1-like complex [nucleoplasm] (Xenopus tropicalis)
ctnnb1 [nucleoplasm] (Xenopus tropicalis)
External Reference Information
External Reference
UniProt:Q28GC2
Gene Names
ctnnb1
Reference Genes
BioGPS Gene:549712 ctnnb1
ENSEMBL:ENSXETG00000013848
KEGG Gene (Xenopus tropicalis):549712 ctnnb1
Monarch:549712 ctnnb1
NCBI Gene:549712 ctnnb1
Reference Transcript
RefSeq:NM_001016958.1 ctnnb1
Participant Of
input
Beta-catenin binds SOX proteins
Beta-catenin displaces TLE:HDAC1 from TCF/LEF
CBY1 binds beta-catenin
CHD8 binds beta-catenin to negatively regulate WNT-dependent gene expression
CTNNBIP1 binds beta-catenin
hasComponent
CBY1:CTNNB1 [nucleoplasm]
CTNNB1:CHD8 [nucleoplasm]
CTNNB1:SRY,SOX2,SOX3,SOX4,SOX6,SOX7,SOX9,SOX17 [nucleoplasm]
CTNNBIP1:CTNNB1 [nucleoplasm]
p-TCF/LEF:CTNNB1 [nucleoplasm]
pS20-CBY1:CTNNB1 [nucleoplasm]
TCF/LEF:CTNNB1 [nucleoplasm]
TCF/LEF:CTNNB1:APC:CTBP:BTRC [nucleoplasm]
TCF/LEF:CTNNB1:BCL9:PYGO [nucleoplasm]
TCF/LEF:CTNNB1:BCL9:PYGO:SET1-like complex [nucleoplasm]
TCF7L1/TCF7L2/LEF1:CTNNB1 [nucleoplasm]
output
Beta-catenin translocates to the nucleus
VENTX disrupts binding of CTNNB1 (beta-catenin) to TCF4 or LEF1
Other forms of this molecule
phospho-ctnnb1 [nucleoplasm]
phospho-ctnnb1 [cytosol]
ctnnb1 [cytosol]
ctnnb1 [cytosol]
ctnnb1 [plasma membrane]
phospho-ctnnb1 [cytosol]
phospho-ctnnb1 [cytosol]
phospho-ctnnb1 [cytosol]
phospho-ctnnb1 [cytosol]
ctnnb1 [cytosol]
Inferred From
CTNNB1 [nucleoplasm] (Homo sapiens)
Cross References
RefSeq
NP_001016958.1
Target Pathogen
5b354852be737e166372e9f6
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