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phospho-slc12a3 [cytosol]
Stable Identifier
R-XTR-354128
Type
Protein [EntityWithAccessionedSequence]
Species
Xenopus tropicalis
Compartment
cytosol
Synonyms
p-6Y-PTK2, F7CW18
Locations in the PathwayBrowser
Expand all
Developmental Biology (Xenopus tropicalis)
Nervous system development (Xenopus tropicalis)
Axon guidance (Xenopus tropicalis)
NCAM signaling for neurite out-growth (Xenopus tropicalis)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Xenopus tropicalis)
Grb2:Sos:pFAK bound to NCAM1:pFyn [plasma membrane] (Xenopus tropicalis)
pFAK:Grb2:Sos [cytosol] (Xenopus tropicalis)
phospho-slc12a3 [cytosol] (Xenopus tropicalis)
Recruitment of Grb2 to pFAK:NCAM1 (Xenopus tropicalis)
Grb2:pFAK bound to NCAM1:pFyn [plasma membrane] (Xenopus tropicalis)
pFAK:Grb2 [cytosol] (Xenopus tropicalis)
phospho-slc12a3 [cytosol] (Xenopus tropicalis)
Multiple phosphorylated FAK bound to NCAM:pFyn [plasma membrane] (Xenopus tropicalis)
phospho-slc12a3 [cytosol] (Xenopus tropicalis)
SOS binds Grb2 bound to pFAK:NCAM1 (Xenopus tropicalis)
Grb2:Sos:pFAK bound to NCAM1:pFyn [plasma membrane] (Xenopus tropicalis)
pFAK:Grb2:Sos [cytosol] (Xenopus tropicalis)
phospho-slc12a3 [cytosol] (Xenopus tropicalis)
Grb2:pFAK bound to NCAM1:pFyn [plasma membrane] (Xenopus tropicalis)
pFAK:Grb2 [cytosol] (Xenopus tropicalis)
phospho-slc12a3 [cytosol] (Xenopus tropicalis)
Hemostasis (Xenopus tropicalis)
Platelet activation, signaling and aggregation (Xenopus tropicalis)
Platelet Aggregation (Plug Formation) (Xenopus tropicalis)
Integrin signaling (Xenopus tropicalis)
GRB2:SOS provides linkage to MAPK signaling for Integrins (Xenopus tropicalis)
Interaction of SOS with GRB2 bound to FADK1 (Xenopus tropicalis)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Xenopus tropicalis)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Xenopus tropicalis)
phospho-slc12a3 [cytosol] (Xenopus tropicalis)
GRB2:SOS:p-PTK2:Focal adhesion [plasma membrane] (Xenopus tropicalis)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Xenopus tropicalis)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Xenopus tropicalis)
phospho-slc12a3 [cytosol] (Xenopus tropicalis)
Recruitment of GRB2 to p-PTK2 (Xenopus tropicalis)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Xenopus tropicalis)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Xenopus tropicalis)
phospho-slc12a3 [cytosol] (Xenopus tropicalis)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Xenopus tropicalis)
phospho-slc12a3 [cytosol] (Xenopus tropicalis)
Phosphorylation of pPTK2 by SRC (Xenopus tropicalis)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Xenopus tropicalis)
phospho-slc12a3 [cytosol] (Xenopus tropicalis)
p130Cas linkage to MAPK signaling for integrins (Xenopus tropicalis)
Crk binding to p130cas (Xenopus tropicalis)
CRK:p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Xenopus tropicalis)
p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Xenopus tropicalis)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Xenopus tropicalis)
phospho-slc12a3 [cytosol] (Xenopus tropicalis)
p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Xenopus tropicalis)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Xenopus tropicalis)
phospho-slc12a3 [cytosol] (Xenopus tropicalis)
Phosphorylation of BCAR1 by SRC-PTK2 complex (Xenopus tropicalis)
BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Xenopus tropicalis)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Xenopus tropicalis)
phospho-slc12a3 [cytosol] (Xenopus tropicalis)
FAK-SRC complex [plasma membrane] (Xenopus tropicalis)
phospho-slc12a3 [cytosol] (Xenopus tropicalis)
p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Xenopus tropicalis)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Xenopus tropicalis)
phospho-slc12a3 [cytosol] (Xenopus tropicalis)
Recruitment of BCAR1 to PTK2 complex (Xenopus tropicalis)
BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Xenopus tropicalis)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Xenopus tropicalis)
phospho-slc12a3 [cytosol] (Xenopus tropicalis)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Xenopus tropicalis)
phospho-slc12a3 [cytosol] (Xenopus tropicalis)
Signal Transduction (Xenopus tropicalis)
Integrin signaling (Xenopus tropicalis)
GRB2:SOS provides linkage to MAPK signaling for Integrins (Xenopus tropicalis)
Interaction of SOS with GRB2 bound to FADK1 (Xenopus tropicalis)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Xenopus tropicalis)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Xenopus tropicalis)
phospho-slc12a3 [cytosol] (Xenopus tropicalis)
GRB2:SOS:p-PTK2:Focal adhesion [plasma membrane] (Xenopus tropicalis)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Xenopus tropicalis)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Xenopus tropicalis)
phospho-slc12a3 [cytosol] (Xenopus tropicalis)
Recruitment of GRB2 to p-PTK2 (Xenopus tropicalis)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Xenopus tropicalis)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Xenopus tropicalis)
phospho-slc12a3 [cytosol] (Xenopus tropicalis)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Xenopus tropicalis)
phospho-slc12a3 [cytosol] (Xenopus tropicalis)
Phosphorylation of pPTK2 by SRC (Xenopus tropicalis)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Xenopus tropicalis)
phospho-slc12a3 [cytosol] (Xenopus tropicalis)
p130Cas linkage to MAPK signaling for integrins (Xenopus tropicalis)
Crk binding to p130cas (Xenopus tropicalis)
CRK:p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Xenopus tropicalis)
p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Xenopus tropicalis)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Xenopus tropicalis)
phospho-slc12a3 [cytosol] (Xenopus tropicalis)
p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Xenopus tropicalis)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Xenopus tropicalis)
phospho-slc12a3 [cytosol] (Xenopus tropicalis)
Phosphorylation of BCAR1 by SRC-PTK2 complex (Xenopus tropicalis)
BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Xenopus tropicalis)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Xenopus tropicalis)
phospho-slc12a3 [cytosol] (Xenopus tropicalis)
FAK-SRC complex [plasma membrane] (Xenopus tropicalis)
phospho-slc12a3 [cytosol] (Xenopus tropicalis)
p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Xenopus tropicalis)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Xenopus tropicalis)
phospho-slc12a3 [cytosol] (Xenopus tropicalis)
Recruitment of BCAR1 to PTK2 complex (Xenopus tropicalis)
BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Xenopus tropicalis)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Xenopus tropicalis)
phospho-slc12a3 [cytosol] (Xenopus tropicalis)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Xenopus tropicalis)
phospho-slc12a3 [cytosol] (Xenopus tropicalis)
MAPK family signaling cascades (Xenopus tropicalis)
MAPK1/MAPK3 signaling (Xenopus tropicalis)
RAF/MAP kinase cascade (Xenopus tropicalis)
RAS GEFs promote RAS nucleotide exchange (Xenopus tropicalis)
RAS GEFs [plasma membrane] (Xenopus tropicalis)
Grb2:Sos:pFAK bound to NCAM1:pFyn [plasma membrane] (Xenopus tropicalis)
pFAK:Grb2:Sos [cytosol] (Xenopus tropicalis)
phospho-slc12a3 [cytosol] (Xenopus tropicalis)
External Reference Information
External Reference
UniProt:F7CW18
Gene Names
slc12a3
Reference Genes
ENSEMBL:ENSXETG00000019997 slc12a3
ENSEMBL:ENSXETG00000023764
Other Identifiers
733890
GO:0001525
GO:0002376
GO:0003674
GO:0004672
GO:0004713
GO:0004715
GO:0005102
GO:0005524
GO:0005575
GO:0005622
GO:0005856
GO:0005886
GO:0005925
GO:0006464
GO:0006468
GO:0006810
GO:0006811
GO:0006814
GO:0006884
GO:0006950
GO:0007155
GO:0007165
GO:0007169
GO:0007172
GO:0007173
GO:0008150
GO:0008283
GO:0008511
GO:0015081
GO:0015293
GO:0015377
GO:0015378
GO:0015379
GO:0016020
GO:0016021
GO:0016301
GO:0016324
GO:0022607
GO:0022857
GO:0030154
GO:0030155
GO:0031234
GO:0035725
GO:0038083
GO:0042127
GO:0042592
GO:0043167
GO:0043197
GO:0043226
GO:0045087
GO:0048646
GO:0048856
GO:0055064
GO:0055075
GO:0055078
GO:0055085
GO:0065003
GO:1902476
GO:1990573
Str.16767.1.S1_at
Participant Of
hasComponent
FAK-SRC complex [plasma membrane]
Multiple phosphorylated FAK bound to NCAM:pFyn [plasma membrane]
pFAK:Grb2 [cytosol]
pFAK:Grb2:Sos [cytosol]
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane]
Other forms of this molecule
phospho-slc12a3 [cytosol]
phospho-slc12a3 [cytosol]
phospho-slc12a3 [cytosol]
slc12a3 [cytosol]
slc12a3 [cytosol]
phospho-slc12a3 [cytosol]
phospho-slc12a3 [cytosol]
phospho-slc12a3 [cytosol]
slc12a3 [cytosol]
phospho-slc12a3 [cytosol]
Inferred From
p-6Y-PTK2 [cytosol] (Homo sapiens)
Modified Residues
Name
O4'-phospho-L-tyrosine at 397 (in Homo sapiens)
Coordinate
397
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 576 (in Homo sapiens)
Coordinate
576
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 577 (in Homo sapiens)
Coordinate
577
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 861 (in Homo sapiens)
Coordinate
861
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 925 (in Homo sapiens)
Coordinate
925
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 407 (in Homo sapiens)
Coordinate
407
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
Ensembl
ENSXETT00000051250
,
ENSXETG00000023764
,
ENSXETP00000051250
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