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dock1 [cytosol]
Stable Identifier
R-XTR-372654
Type
Protein [EntityWithAccessionedSequence]
Species
Xenopus tropicalis
Compartment
cytosol
Synonyms
DOCK1, A0A6I8Q431
Locations in the PathwayBrowser
Expand all
Developmental Biology (Xenopus tropicalis)
Nervous system development (Xenopus tropicalis)
Axon guidance (Xenopus tropicalis)
Netrin-1 signaling (Xenopus tropicalis)
DCC mediated attractive signaling (Xenopus tropicalis)
Activation of Cdc42 (Xenopus tropicalis)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Xenopus tropicalis)
dock1 [cytosol] (Xenopus tropicalis)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP [plasma membrane] (Xenopus tropicalis)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Xenopus tropicalis)
dock1 [cytosol] (Xenopus tropicalis)
dock1 [cytosol] (Xenopus tropicalis)
Activation of Rac1 (Xenopus tropicalis)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Xenopus tropicalis)
dock1 [cytosol] (Xenopus tropicalis)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:RAC1:GTP [plasma membrane] (Xenopus tropicalis)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Xenopus tropicalis)
dock1 [cytosol] (Xenopus tropicalis)
dock1 [cytosol] (Xenopus tropicalis)
RhoGTPase GEF's recruited to DCC (Xenopus tropicalis)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Xenopus tropicalis)
dock1 [cytosol] (Xenopus tropicalis)
dock1 [cytosol] (Xenopus tropicalis)
Hemostasis (Xenopus tropicalis)
Factors involved in megakaryocyte development and platelet production (Xenopus tropicalis)
DOCKs bind to RhoGEFs (Xenopus tropicalis)
DOCK-GEFs [cytosol] (Xenopus tropicalis)
dock1 [cytosol] (Xenopus tropicalis)
DOCK-GEFs:RAC1, CDC42 [cytosol] (Xenopus tropicalis)
DOCK-GEFs [cytosol] (Xenopus tropicalis)
dock1 [cytosol] (Xenopus tropicalis)
Signal Transduction (Xenopus tropicalis)
Signaling by Non-Receptor Tyrosine Kinases (Xenopus tropicalis)
Signaling by PTK6 (Xenopus tropicalis)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Xenopus tropicalis)
Activation of RAC1 by the PXN:CRK complex (Xenopus tropicalis)
p-Y31,Y118-PXN:CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Xenopus tropicalis)
CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Xenopus tropicalis)
dock1 [cytosol] (Xenopus tropicalis)
Signaling by Receptor Tyrosine Kinases (Xenopus tropicalis)
Signaling by VEGF (Xenopus tropicalis)
VEGFA-VEGFR2 Pathway (Xenopus tropicalis)
DOCK180:ELMO binds CRK (Xenopus tropicalis)
CRK:DOCK180:ELMO1,ELMO2:VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Xenopus tropicalis)
CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Xenopus tropicalis)
dock1 [cytosol] (Xenopus tropicalis)
DOCK180:ELMO1,ELMO2 [cytosol] (Xenopus tropicalis)
dock1 [cytosol] (Xenopus tropicalis)
DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Xenopus tropicalis)
CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Xenopus tropicalis)
dock1 [cytosol] (Xenopus tropicalis)
CRK:DOCK180:ELMO1,ELMO2:VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Xenopus tropicalis)
CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Xenopus tropicalis)
dock1 [cytosol] (Xenopus tropicalis)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Xenopus tropicalis)
Signaling by Rho GTPases (Xenopus tropicalis)
RHO GTPase cycle (Xenopus tropicalis)
RAC1 GTPase cycle (Xenopus tropicalis)
RAC1 GEFs activate RAC1 (Xenopus tropicalis)
RAC1 GEFs [cytosol] (Xenopus tropicalis)
dock1 [cytosol] (Xenopus tropicalis)
RAC2 GTPase cycle (Xenopus tropicalis)
RAC2 GEFs activate RAC2 (Xenopus tropicalis)
RAC2 GEFs [cytosol] (Xenopus tropicalis)
dock1 [cytosol] (Xenopus tropicalis)
RHOG GTPase cycle (Xenopus tropicalis)
RHOG binds effectors at the plasma membrane (Xenopus tropicalis)
RHOG plasma membrane effectors [cytosol] (Xenopus tropicalis)
dock1 [cytosol] (Xenopus tropicalis)
RHOG:GTP:RHOG plasma membrane effectors [plasma membrane] (Xenopus tropicalis)
RHOG plasma membrane effectors [cytosol] (Xenopus tropicalis)
dock1 [cytosol] (Xenopus tropicalis)
External Reference Information
External Reference
UniProt:A0A6I8Q431
Gene Names
dock1
Reference Genes
BioGPS Gene:100497783 dock1
ENSEMBL:ENSXETG00000005204
Monarch:100497783 dock1
NCBI Gene:100497783 dock1
Reference Transcript
RefSeq:XM_012959631.3 dock1
Other Identifiers
100497783
GO:0005085
GO:0005737
GO:0007264
GO:0023052
GO:0098772
Participates
as a candidate of
RAC2 GEFs [cytosol] (Xenopus tropicalis)
RAC1 GEFs [cytosol] (Xenopus tropicalis)
as a member of
RHOG plasma membrane effectors [cytosol] (Xenopus tropicalis)
DOCK-GEFs [cytosol] (Xenopus tropicalis)
as a component of
DOCK180:ELMO1,ELMO2 [cytosol] (Xenopus tropicalis)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Xenopus tropicalis)
CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Xenopus tropicalis)
as an input of
RhoGTPase GEF's recruited to DCC (Xenopus tropicalis)
Inferred From
DOCK1,TRIO [cytosol]
(Homo sapiens)
DOCK1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_012815085.1
Ensembl
ENSXETP00000067259
,
ENSXETT00000074722
,
ENSXETG00000005204
Xenbase
XB-GENE-1010793
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