Reactome | cep43 [cytosol]

cep43 [cytosol]

Stable Identifier

R-XTR-380309

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

cytosol

Synonyms

FGFR1OP, A0A6I8PY26

Locations in the PathwayBrowser

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Organelle biogenesis and maintenance (Xenopus tropicalis)

- Cilium Assembly (Xenopus tropicalis)
  - Anchoring of the basal body to the plasma membrane (Xenopus tropicalis)
    - C2CD3 binds the mother centriole (Xenopus tropicalis)
      - mother centriole [cytosol] (Xenopus tropicalis)
        
        cep43 [cytosol] (Xenopus tropicalis)
      - mother centriole:C2CD3 [cytosol] (Xenopus tropicalis)
        
        mother centriole [cytosol] (Xenopus tropicalis)
        
        cep43 [cytosol] (Xenopus tropicalis)
    - CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body (Xenopus tropicalis)
      - basal body:transition zone proteins [cytosol] (Xenopus tropicalis)
        
        basal body [cytosol] (Xenopus tropicalis)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Xenopus tropicalis)
        
        cep43 [cytosol] (Xenopus tropicalis)
      - basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Xenopus tropicalis)
        
        basal body:transition zone proteins [cytosol] (Xenopus tropicalis)
        
        basal body [cytosol] (Xenopus tropicalis)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Xenopus tropicalis)
        
        cep43 [cytosol] (Xenopus tropicalis)
    - CP110 and CEP97 dissociate from the centriole (Xenopus tropicalis)
      - basal body [cytosol] (Xenopus tropicalis)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Xenopus tropicalis)
        
        cep43 [cytosol] (Xenopus tropicalis)
      - centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Xenopus tropicalis)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Xenopus tropicalis)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Xenopus tropicalis)
        
        mother centriole:C2CD3 [cytosol] (Xenopus tropicalis)
        
        mother centriole [cytosol] (Xenopus tropicalis)
        
        cep43 [cytosol] (Xenopus tropicalis)
    - RAB3IP stimulates nucleotide exchange on RAB8A (Xenopus tropicalis)
      - basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Xenopus tropicalis)
        
        basal body:transition zone proteins [cytosol] (Xenopus tropicalis)
        
        basal body [cytosol] (Xenopus tropicalis)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Xenopus tropicalis)
        
        cep43 [cytosol] (Xenopus tropicalis)
    - The distal appendage proteins recruit TTBK2 (Xenopus tropicalis)
      - Centrosome:C2CD3:distal appendage proteins [cytosol] (Xenopus tropicalis)
        
        mother centriole:C2CD3 [cytosol] (Xenopus tropicalis)
        
        mother centriole [cytosol] (Xenopus tropicalis)
        
        cep43 [cytosol] (Xenopus tropicalis)
      - Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Xenopus tropicalis)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Xenopus tropicalis)
        
        mother centriole:C2CD3 [cytosol] (Xenopus tropicalis)
        
        mother centriole [cytosol] (Xenopus tropicalis)
        
        cep43 [cytosol] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:A0A6I8PY26

Gene Names

cep43

Reference Genes

BioGPS Gene:549512 cep43

ENSEMBL:ENSXETG00000014534

Monarch:549512 cep43

NCBI Gene:549512 cep43

Reference Transcript

RefSeq:XM_018093891.1 cep43

Other Identifiers

549512

GO:0005509

GO:0005515

GO:0005815

GO:0005856

GO:0007010

GO:0030030

GO:0034453

GO:0043226

GO:0046872

Participates

as a component of

Inferred From

FGFR1OP [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_017949380.1

Xenbase

XB-GENE-5752647

Ensembl

ENSXETP00000059191, ENSXETT00000065598, ENSXETG00000014534

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