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cdc42 [plasma membrane]
Stable Identifier
R-XTR-449545
Type
Protein [EntityWithAccessionedSequence]
Species
Xenopus tropicalis
Compartment
plasma membrane
Synonyms
CDC42, Q28BZ0
Locations in the PathwayBrowser
Expand all
Developmental Biology (Xenopus tropicalis)
Myogenesis (Xenopus tropicalis)
Nuclear translocation of p38 MAPK (Xenopus tropicalis)
ABL1:JLP:CDO complex [plasma membrane] (Xenopus tropicalis)
Cadherin-catenin:JLP:CDO:BOC:Bnip2-Cdc42 [plasma membrane] (Xenopus tropicalis)
Cadherin-catenin:CDO:BOC:Bnip2:CDC42-GTP [plasma membrane] (Xenopus tropicalis)
CDC42:GTP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
pp38 alpha/beta/gamma:ABL1:JLP:CDO complex [plasma membrane] (Xenopus tropicalis)
ABL1:JLP:CDO complex [plasma membrane] (Xenopus tropicalis)
Cadherin-catenin:JLP:CDO:BOC:Bnip2-Cdc42 [plasma membrane] (Xenopus tropicalis)
Cadherin-catenin:CDO:BOC:Bnip2:CDC42-GTP [plasma membrane] (Xenopus tropicalis)
CDC42:GTP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
Nervous system development (Xenopus tropicalis)
Axon guidance (Xenopus tropicalis)
Netrin-1 signaling (Xenopus tropicalis)
DCC mediated attractive signaling (Xenopus tropicalis)
Activation of Cdc42 (Xenopus tropicalis)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP [plasma membrane] (Xenopus tropicalis)
CDC42:GTP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
Immune System (Xenopus tropicalis)
Adaptive Immune System (Xenopus tropicalis)
Regulation of T cell activation by CD28 family (Xenopus tropicalis)
Co-stimulation by CD28 (Xenopus tropicalis)
CD28 dependent Vav1 pathway (Xenopus tropicalis)
Activation of Cdc42 by pVav1 (Xenopus tropicalis)
CDC42:GTP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
Activation of PAKs by RAC1 and CDC42 (Xenopus tropicalis)
CDC42:GTP, RAC1:GTP [plasma membrane] (Xenopus tropicalis)
CDC42:GTP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] (Xenopus tropicalis)
CDC42:GTP, RAC1:GTP [plasma membrane] (Xenopus tropicalis)
CDC42:GTP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
Innate Immune System (Xenopus tropicalis)
Fcgamma receptor (FCGR) dependent phagocytosis (Xenopus tropicalis)
Regulation of actin dynamics for phagocytic cup formation (Xenopus tropicalis)
Autophosphorylation of PAK1 (Xenopus tropicalis)
CDC42:GTP, RAC1:GTP [plasma membrane] (Xenopus tropicalis)
CDC42:GTP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Xenopus tropicalis)
CDC42:GTP, RAC1:GTP [plasma membrane] (Xenopus tropicalis)
CDC42:GTP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
RAC1 and CDC42 activate PAK1 (Xenopus tropicalis)
CDC42:GTP, RAC1:GTP [plasma membrane] (Xenopus tropicalis)
CDC42:GTP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Xenopus tropicalis)
CDC42:GTP, RAC1:GTP [plasma membrane] (Xenopus tropicalis)
CDC42:GTP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
Signal Transduction (Xenopus tropicalis)
MAPK family signaling cascades (Xenopus tropicalis)
MAPK6/MAPK4 signaling (Xenopus tropicalis)
Activation of PAKs by RAC1 and CDC42 (Xenopus tropicalis)
CDC42:GTP, RAC1:GTP [plasma membrane] (Xenopus tropicalis)
CDC42:GTP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] (Xenopus tropicalis)
CDC42:GTP, RAC1:GTP [plasma membrane] (Xenopus tropicalis)
CDC42:GTP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
Autophosphorylation of PAK1,2,3 (Xenopus tropicalis)
CDC42:GTP, RAC1:GTP [plasma membrane] (Xenopus tropicalis)
CDC42:GTP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
CDC42:GTP,RAC1:GTP:PAK1,PAK2,PAK3 [plasma membrane] (Xenopus tropicalis)
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] (Xenopus tropicalis)
CDC42:GTP, RAC1:GTP [plasma membrane] (Xenopus tropicalis)
CDC42:GTP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Xenopus tropicalis)
CDC42:GTP, RAC1:GTP [plasma membrane] (Xenopus tropicalis)
CDC42:GTP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
Signaling by GPCR (Xenopus tropicalis)
GPCR downstream signalling (Xenopus tropicalis)
G-protein beta:gamma signalling (Xenopus tropicalis)
G beta:gamma signalling through CDC42 (Xenopus tropicalis)
Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex (Xenopus tropicalis)
CDC42:GTP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
G-protein beta-gamma complex:Active PAK1:ARHGEF6:Active CDC42 [plasma membrane] (Xenopus tropicalis)
CDC42:GTP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
CDC42 binds GNB/GNG:PAK1:ARHGEF6 complex (Xenopus tropicalis)
G-protein beta-gamma complex:PAK1:ARHGEF6:CDC42 [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
CDC42 in GNB/GNG:PAK1:ARHGEF6:CDC42 is activated (Xenopus tropicalis)
G-protein beta-gamma complex:Active PAK1:ARHGEF6:Active CDC42 [plasma membrane] (Xenopus tropicalis)
CDC42:GTP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
G-protein beta-gamma complex:PAK1:ARHGEF6:CDC42 [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
PAK1 in GNB/GNG:PAK1:ARHGEF6:Active CDC42 is activated (Xenopus tropicalis)
G-protein beta-gamma complex:Active PAK1:ARHGEF6:Active CDC42 [plasma membrane] (Xenopus tropicalis)
CDC42:GTP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
Signaling by Receptor Tyrosine Kinases (Xenopus tropicalis)
Signaling by EGFR (Xenopus tropicalis)
EGFR downregulation (Xenopus tropicalis)
CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix (Xenopus tropicalis)
EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP [plasma membrane] (Xenopus tropicalis)
Beta-Pix:CDC42:GTP [cytosol] (Xenopus tropicalis)
CDC42:GTP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
Ub-Beta-Pix:CDC42:GTP [cytosol] (Xenopus tropicalis)
CDC42:GTP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
Signaling by VEGF (Xenopus tropicalis)
VEGFA-VEGFR2 Pathway (Xenopus tropicalis)
CDC42:GTP binds PAK2 (Xenopus tropicalis)
CDC42:GTP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:PAK2:CDC42:GTP [plasma membrane] (Xenopus tropicalis)
PAK2 dimer:CDC42:GTP [plasma membrane] (Xenopus tropicalis)
CDC42:GTP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
FYN phosphorylates PAK2 (Xenopus tropicalis)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-2Y-PAK2:CDC42:GTP [plasma membrane] (Xenopus tropicalis)
p-2Y-PAK2 dimer:CDC42:GTP [plasma membrane] (Xenopus tropicalis)
CDC42:GTP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-3Y-PAK2:CDC42:GTP [plasma membrane] (Xenopus tropicalis)
p-3Y-PAK2 dimer:CDC42:GTP [plasma membrane] (Xenopus tropicalis)
CDC42:GTP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
PAK2 autophorylates (Xenopus tropicalis)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:PAK2:CDC42:GTP [plasma membrane] (Xenopus tropicalis)
PAK2 dimer:CDC42:GTP [plasma membrane] (Xenopus tropicalis)
CDC42:GTP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-2Y-PAK2:CDC42:GTP [plasma membrane] (Xenopus tropicalis)
p-2Y-PAK2 dimer:CDC42:GTP [plasma membrane] (Xenopus tropicalis)
CDC42:GTP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
p38 MAPK activation by VEGFR (Xenopus tropicalis)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-3Y-PAK2:CDC42:GTP [plasma membrane] (Xenopus tropicalis)
p-3Y-PAK2 dimer:CDC42:GTP [plasma membrane] (Xenopus tropicalis)
CDC42:GTP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Xenopus tropicalis)
Signaling by Rho GTPases (Xenopus tropicalis)
RHO GTPase Effectors (Xenopus tropicalis)
RHO GTPases activate IQGAPs (Xenopus tropicalis)
GTP-bound RAC1 and CDC42 bind IQGAPs (Xenopus tropicalis)
CDC42:GTP, RAC1:GTP [plasma membrane] (Xenopus tropicalis)
CDC42:GTP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Xenopus tropicalis)
CDC42:GTP, RAC1:GTP [plasma membrane] (Xenopus tropicalis)
CDC42:GTP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
IQGAPs bind F-actin, which is inhibited by calmodulin (Xenopus tropicalis)
RAC1,CDC42:GTP:IQGAP:F-actin [plasma membrane] (Xenopus tropicalis)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Xenopus tropicalis)
CDC42:GTP, RAC1:GTP [plasma membrane] (Xenopus tropicalis)
CDC42:GTP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Xenopus tropicalis)
CDC42:GTP, RAC1:GTP [plasma membrane] (Xenopus tropicalis)
CDC42:GTP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
RHO GTPases activate PAKs (Xenopus tropicalis)
Autophosphorylation of PAK1,2,3 (Xenopus tropicalis)
CDC42:GTP, RAC1:GTP [plasma membrane] (Xenopus tropicalis)
CDC42:GTP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
CDC42:GTP,RAC1:GTP:PAK1,PAK2,PAK3 [plasma membrane] (Xenopus tropicalis)
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] (Xenopus tropicalis)
CDC42:GTP, RAC1:GTP [plasma membrane] (Xenopus tropicalis)
CDC42:GTP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Xenopus tropicalis)
CDC42:GTP, RAC1:GTP [plasma membrane] (Xenopus tropicalis)
CDC42:GTP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
RAC1 and CDC42 activate PAK1 (Xenopus tropicalis)
CDC42:GTP, RAC1:GTP [plasma membrane] (Xenopus tropicalis)
CDC42:GTP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Xenopus tropicalis)
CDC42:GTP, RAC1:GTP [plasma membrane] (Xenopus tropicalis)
CDC42:GTP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
RAC1 and CDC42 activate PAK3 (Xenopus tropicalis)
CDC42:GTP, RAC1:GTP [plasma membrane] (Xenopus tropicalis)
CDC42:GTP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] (Xenopus tropicalis)
CDC42:GTP, RAC1:GTP [plasma membrane] (Xenopus tropicalis)
CDC42:GTP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
RHO GTPase cycle (Xenopus tropicalis)
CDC42 GTPase cycle (Xenopus tropicalis)
CDC42 GAPs stimulate CDC42 GTPase activity (Xenopus tropicalis)
CDC42:GDP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
CDC42:GTP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
CDC42 GDIs block activation of CDC42 (Xenopus tropicalis)
CDC42:GDP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
CDC42 GEFs activate CDC42 (Xenopus tropicalis)
CDC42:GDP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
CDC42:GTP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
CDC42 translocates to the endoplasmic reticulum membrane (Xenopus tropicalis)
CDC42:GTP [plasma membrane] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
RHOG GTPase cycle (Xenopus tropicalis)
RHOG binds effectors at the plasma membrane (Xenopus tropicalis)
RHOG plasma membrane effectors [cytosol] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
RHOG:GTP:RHOG plasma membrane effectors [plasma membrane] (Xenopus tropicalis)
RHOG plasma membrane effectors [cytosol] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
RHOQ GTPase cycle (Xenopus tropicalis)
RHOQ binds effectors at the plasma membrane (Xenopus tropicalis)
RHOQ effectors [cytosol] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
RHOQ:GTP:RHOQ effectors [plasma membrane] (Xenopus tropicalis)
RHOQ effectors [cytosol] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
RHOU GTPase cycle (Xenopus tropicalis)
RHOU binds effectors at the plasma membrane (Xenopus tropicalis)
RHOU effectors [cytosol] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
RHOU:GTP:RHOU effectors [plasma membrane] (Xenopus tropicalis)
RHOU effectors [cytosol] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
RHOV GTPase cycle (Xenopus tropicalis)
RHOV binds effectors at the plasma membrane (Xenopus tropicalis)
RHOV effectors [cytosol] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
RHOV:GTP:RHOV effectors [plasma membrane] (Xenopus tropicalis)
RHOV effectors [cytosol] (Xenopus tropicalis)
cdc42 [plasma membrane] (Xenopus tropicalis)
External Reference Information
External Reference
UniProt:Q28BZ0
Gene Names
cdc42
Reference Genes
BioGPS Gene:493389 cdc42
ENSEMBL:ENSXETG00000004743
Monarch:493389 cdc42
NCBI Gene:493389 cdc42
UCSC:Q28BZ0 cdc42
Reference Transcript
RefSeq:XM_031905014.1 cdc42
RefSeq:NM_001017070.4 cdc42
RefSeq:XM_031905015.1 cdc42
Other Identifiers
493389
GO:0000166
GO:0003824
GO:0003924
GO:0003925
GO:0005525
GO:0005737
GO:0005813
GO:0005815
GO:0005819
GO:0005856
GO:0005886
GO:0005938
GO:0007163
GO:0007264
GO:0007399
GO:0009653
GO:0016020
GO:0016787
GO:0023052
GO:0030154
GO:0030496
GO:0042995
GO:0043226
GO:0043227
GO:0048856
GO:0051130
GO:0051301
GO:0071944
GO:0098772
Participates
as a candidate of
RHOV effectors [cytosol] (Xenopus tropicalis)
RHOQ effectors [cytosol] (Xenopus tropicalis)
RHOG plasma membrane effectors [cytosol] (Xenopus tropicalis)
RHOJ effectors [cytosol] (Xenopus tropicalis)
RHOU effectors [cytosol] (Xenopus tropicalis)
as a component of
CDC42:GDP [plasma membrane] (Xenopus tropicalis)
G-protein beta-gamma complex:PAK1:ARHGEF6:CDC42 [plasma membrane] (Xenopus tropicalis)
CDC42-GDP [plasma membrane] (Xenopus tropicalis)
CDC42:GTP [plasma membrane] (Xenopus tropicalis)
as an input of
CDC42 binds GNB/GNG:PAK1:ARHGEF6 complex (Xenopus tropicalis)
Other forms of this molecule
cdc42 [endoplasmic reticulum membrane]
cdc42 [cytosol]
Inferred From
CDC42 [plasma membrane]
(Homo sapiens)
Cross References
RefSeq
NP_001017070.1
,
XP_031760875.1
,
XP_031760874.1
ENSEMBL
ENSXETT00000111040
,
ENSXETP00000102295
Xenbase
XB-GENE-967585
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