Reactome | uba52 [nucleoplasm]

uba52 [nucleoplasm]

Stable Identifier

R-XTR-5653745

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

nucleoplasm

Synonyms

K164-PCNA-G157-ISG15, Q6AZL4

Locations in the PathwayBrowser

Expand all

DNA Repair (Xenopus tropicalis)

- DNA Damage Bypass (Xenopus tropicalis)
  - Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template (Xenopus tropicalis)
    - Termination of translesion DNA synthesis (Xenopus tropicalis)
      - UBE2L6:TRIM25 ISGylates monoUb:K164-PCNA (Xenopus tropicalis)
        
        DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Xenopus tropicalis)
        
        MonoUb:K164,ISG:K164,ISG:K168-PCNA homotrimer [nucleoplasm] (Xenopus tropicalis)
        
        ISG:K164,ISG:K168-PCNA [nucleoplasm] (Xenopus tropicalis)
        
        uba52 [nucleoplasm] (Xenopus tropicalis)
      - USP10 binds monoUb:K164,ISG:K164,ISG:K168-PCNA (Xenopus tropicalis)
        
        DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Xenopus tropicalis)
        
        MonoUb:K164,ISG:K164,ISG:K168-PCNA homotrimer [nucleoplasm] (Xenopus tropicalis)
        
        ISG:K164,ISG:K168-PCNA [nucleoplasm] (Xenopus tropicalis)
        
        uba52 [nucleoplasm] (Xenopus tropicalis)
        
        USP10:DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Xenopus tropicalis)
        
        DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Xenopus tropicalis)
        
        MonoUb:K164,ISG:K164,ISG:K168-PCNA homotrimer [nucleoplasm] (Xenopus tropicalis)
        
        ISG:K164,ISG:K168-PCNA [nucleoplasm] (Xenopus tropicalis)
        
        uba52 [nucleoplasm] (Xenopus tropicalis)
      - USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA (Xenopus tropicalis)
        
        ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Xenopus tropicalis)
        
        ISG:K164,ISG:K168-PCNA homotrimer [nucleoplasm] (Xenopus tropicalis)
        
        ISG:K164,ISG:K168-PCNA [nucleoplasm] (Xenopus tropicalis)
        
        uba52 [nucleoplasm] (Xenopus tropicalis)
        
        USP10:DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Xenopus tropicalis)
        
        DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Xenopus tropicalis)
        
        MonoUb:K164,ISG:K164,ISG:K168-PCNA homotrimer [nucleoplasm] (Xenopus tropicalis)
        
        ISG:K164,ISG:K168-PCNA [nucleoplasm] (Xenopus tropicalis)
        
        uba52 [nucleoplasm] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:Q6AZL4

Gene Names

uba52

Reference Genes

BioGPS Gene:448705 uba52

ENSEMBL:ENSXETG00000004009 uba52

ENSEMBL:ENSXETG00000023202

KEGG Gene (Xenopus tropicalis):448705 uba52

Monarch:448705 uba52

NCBI Gene:448705 uba52

Reference Transcript

Other Identifiers

100493467

GO:0000124

GO:0003674

GO:0003713

GO:0003735

GO:0005198

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005669

GO:0005737

GO:0005829

GO:0005840

GO:0006325

GO:0006352

GO:0006357

GO:0006367

GO:0006412

GO:0006464

GO:0008150

GO:0009056

GO:0009058

GO:0015935

GO:0016251

GO:0016567

GO:0019899

GO:0019941

GO:0022607

GO:0022627

GO:0031386

GO:0031625

GO:0032991

GO:0034641

GO:0043226

GO:0046695

GO:0046982

GO:0051123

GO:0051276

GO:0060261

GO:0065003

Participant Of

hasComponent

ISG:K164,ISG:K168-PCNA [nucleoplasm]

Other forms of this molecule

uba52 [endocytic vesicle membrane]

uba52 [mitochondrial outer membrane]

uba52 [cytosol]

phospho-uba52 [nucleoplasm]

uba52 [cytosol]

phospho-uba52 [cytosol]

uba52 [nucleoplasm]

uba52 [endosome membrane]

uba52 [cytosol]

uba52 [nucleoplasm]

uba52 [cytosol]

Inferred From

K168-PCNA-G157-ISG15 [nucleoplasm] (Homo sapiens)

K164-PCNA-G157-ISG15 [nucleoplasm] (Homo sapiens)

Modified Residues

Name

Inter-chain Crosslink via N6-glycyl-L-lysine at 157 and 164 (in Homo sapiens)

Coordinate

157

PsiMod Name

N6-glycyl-L-lysine

PsiMod Definition

A protein modification that effectively crosslinks an L-lysine residue and a glycine residue by an isopeptide bond to form N6-glycyl-L-lysine.

Cross References

RefSeq

NP_001005123.1, XP_012819998.1, XP_017947893.1

Target Pathogen

5b354852be737e166372eb5f, 5b2801b2be737e35a6de9e91, 5b354852be737e166372eb07, 5b2801b3be737e35a6deded6, 5b2801b2be737e35a6de9681, 57c5e0e8be737e5a0cb48b62

Ensembl

ENSXETG00000004009, ENSXETP00000008691, ENSXETT00000008691