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uba52 [cytosol]
Stable Identifier
R-XTR-72476
Type
Protein [EntityWithAccessionedSequence]
Species
Xenopus tropicalis
Compartment
cytosol
Synonyms
RPL40, Q6AZL4
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Xenopus tropicalis)
Nonsense-Mediated Decay (NMD) (Xenopus tropicalis)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Xenopus tropicalis)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Xenopus tropicalis)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Xenopus tropicalis)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Xenopus tropicalis)
80S ribosome [cytosol] (Xenopus tropicalis)
60S ribosomal complex [cytosol] (Xenopus tropicalis)
uba52 [cytosol] (Xenopus tropicalis)
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Xenopus tropicalis)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Xenopus tropicalis)
80S ribosome [cytosol] (Xenopus tropicalis)
60S ribosomal complex [cytosol] (Xenopus tropicalis)
uba52 [cytosol] (Xenopus tropicalis)
SMG6 hydrolyzes mRNA with premature termination codon (Xenopus tropicalis)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Xenopus tropicalis)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Xenopus tropicalis)
80S ribosome [cytosol] (Xenopus tropicalis)
60S ribosomal complex [cytosol] (Xenopus tropicalis)
uba52 [cytosol] (Xenopus tropicalis)
p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Xenopus tropicalis)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Xenopus tropicalis)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Xenopus tropicalis)
80S ribosome [cytosol] (Xenopus tropicalis)
60S ribosomal complex [cytosol] (Xenopus tropicalis)
uba52 [cytosol] (Xenopus tropicalis)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Xenopus tropicalis)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Xenopus tropicalis)
80S ribosome [cytosol] (Xenopus tropicalis)
60S ribosomal complex [cytosol] (Xenopus tropicalis)
uba52 [cytosol] (Xenopus tropicalis)
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Xenopus tropicalis)
Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Xenopus tropicalis)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Xenopus tropicalis)
80S ribosome [cytosol] (Xenopus tropicalis)
60S ribosomal complex [cytosol] (Xenopus tropicalis)
uba52 [cytosol] (Xenopus tropicalis)
UPF1:eRF3 Complex on Translated mRNA [cytosol] (Xenopus tropicalis)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Xenopus tropicalis)
80S ribosome [cytosol] (Xenopus tropicalis)
60S ribosomal complex [cytosol] (Xenopus tropicalis)
uba52 [cytosol] (Xenopus tropicalis)
Metabolism of proteins (Xenopus tropicalis)
Post-translational protein modification (Xenopus tropicalis)
Protein ubiquitination (Xenopus tropicalis)
Synthesis of active ubiquitin: roles of E1 and E2 enzymes (Xenopus tropicalis)
UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin (Xenopus tropicalis)
uba52 [cytosol] (Xenopus tropicalis)
Translation (Xenopus tropicalis)
Eukaryotic Translation Initiation (Xenopus tropicalis)
Cap-dependent Translation Initiation (Xenopus tropicalis)
Formation of a pool of free 40S subunits (Xenopus tropicalis)
Release of 40S and 60S subunits from the 80S ribosome (Xenopus tropicalis)
60S ribosomal complex [cytosol] (Xenopus tropicalis)
uba52 [cytosol] (Xenopus tropicalis)
80S ribosome [cytosol] (Xenopus tropicalis)
60S ribosomal complex [cytosol] (Xenopus tropicalis)
uba52 [cytosol] (Xenopus tropicalis)
GTP hydrolysis and joining of the 60S ribosomal subunit (Xenopus tropicalis)
The 60S subunit joins the translation initiation complex (Xenopus tropicalis)
60S ribosomal complex [cytosol] (Xenopus tropicalis)
uba52 [cytosol] (Xenopus tropicalis)
80S:Met-tRNAi:mRNA:eIF5B:GTP [cytosol] (Xenopus tropicalis)
80S ribosome [cytosol] (Xenopus tropicalis)
60S ribosomal complex [cytosol] (Xenopus tropicalis)
uba52 [cytosol] (Xenopus tropicalis)
eIF5B:GTP is hydrolyzed and released (Xenopus tropicalis)
80S:Met-tRNAi:mRNA [cytosol] (Xenopus tropicalis)
80S ribosome [cytosol] (Xenopus tropicalis)
60S ribosomal complex [cytosol] (Xenopus tropicalis)
uba52 [cytosol] (Xenopus tropicalis)
80S:Met-tRNAi:mRNA:eIF5B:GTP [cytosol] (Xenopus tropicalis)
80S ribosome [cytosol] (Xenopus tropicalis)
60S ribosomal complex [cytosol] (Xenopus tropicalis)
uba52 [cytosol] (Xenopus tropicalis)
L13a-mediated translational silencing of Ceruloplasmin expression (Xenopus tropicalis)
Dissociation of L13a from the 60s ribosomal subunit (Xenopus tropicalis)
60S ribosomal complex [cytosol] (Xenopus tropicalis)
uba52 [cytosol] (Xenopus tropicalis)
60s ribosomal complex lacking L13a subunit [cytosol] (Xenopus tropicalis)
uba52 [cytosol] (Xenopus tropicalis)
SRP-dependent cotranslational protein targeting to membrane (Xenopus tropicalis)
Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) (Xenopus tropicalis)
SRP:polypeptide+signal:ribosome [cytosol] (Xenopus tropicalis)
ribosome:mRNA:polypeptide+signal [cytosol] (Xenopus tropicalis)
80S ribosome [cytosol] (Xenopus tropicalis)
60S ribosomal complex [cytosol] (Xenopus tropicalis)
uba52 [cytosol] (Xenopus tropicalis)
ribosome:mRNA:polypeptide+signal [cytosol] (Xenopus tropicalis)
80S ribosome [cytosol] (Xenopus tropicalis)
60S ribosomal complex [cytosol] (Xenopus tropicalis)
uba52 [cytosol] (Xenopus tropicalis)
External Reference Information
External Reference
UniProt:Q6AZL4
Gene Names
uba52
Reference Genes
BioGPS Gene:448705 uba52
ENSEMBL:ENSXETG00000004009 uba52
ENSEMBL:ENSXETG00000023202
KEGG Gene (Xenopus tropicalis):448705 uba52
Monarch:448705 uba52
NCBI Gene:448705 uba52
Reference Transcript
RefSeq:XM_018092404.1 uba52
RefSeq:XM_012964544.1 uba52
RefSeq:NM_001005123.1 uba52
Other Identifiers
100493467
GO:0000124
GO:0003674
GO:0003713
GO:0003735
GO:0005198
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005669
GO:0005737
GO:0005829
GO:0005840
GO:0006325
GO:0006352
GO:0006357
GO:0006367
GO:0006412
GO:0006464
GO:0008150
GO:0009056
GO:0009058
GO:0015935
GO:0016251
GO:0016567
GO:0019899
GO:0019941
GO:0022607
GO:0022627
GO:0031386
GO:0031625
GO:0032991
GO:0034641
GO:0043226
GO:0046695
GO:0046982
GO:0051123
GO:0051276
GO:0060261
GO:0065003
Participant Of
hasComponent
60S ribosomal complex [cytosol]
60s ribosomal complex lacking L13a subunit [cytosol]
output
UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin
Other forms of this molecule
uba52 [endocytic vesicle membrane]
uba52 [mitochondrial outer membrane]
uba52 [mitochondrial outer membrane]
uba52 [mitochondrial outer membrane]
uba52 [mitochondrial outer membrane]
uba52 [mitochondrial outer membrane]
uba52 [mitochondrial outer membrane]
uba52 [mitochondrial outer membrane]
uba52 [cytosol]
phospho-uba52 [nucleoplasm]
uba52 [cytosol]
phospho-uba52 [cytosol]
uba52 [nucleoplasm]
uba52 [nucleoplasm]
uba52 [endosome membrane]
uba52 [cytosol]
uba52 [cytosol]
uba52 [cytosol]
uba52 [nucleoplasm]
uba52 [nucleoplasm]
uba52 [nucleoplasm]
uba52 [nucleoplasm]
uba52 [nucleoplasm]
uba52 [nucleoplasm]
uba52 [nucleoplasm]
uba52 [nucleoplasm]
uba52 [cytosol]
uba52 [cytosol]
uba52 [cytosol]
uba52 [cytosol]
uba52 [cytosol]
uba52 [cytosol]
Inferred From
RPL40 [cytosol] (Homo sapiens)
Cross References
RefSeq
NP_001005123.1
,
XP_012819998.1
,
XP_017947893.1
Target Pathogen
5b354852be737e166372eb5f
,
5b2801b2be737e35a6de9e91
,
5b354852be737e166372eb07
,
5b2801b3be737e35a6deded6
,
5b2801b2be737e35a6de9681
,
57c5e0e8be737e5a0cb48b62
Ensembl
ENSXETG00000004009
,
ENSXETP00000008691
,
ENSXETT00000008691
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