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UniProt:P01375 TNF
Type
Interactor (Protein)
Species
Homo sapiens
Synonyms
TNFA_HUMAN, O43647, Q9P1Q2, Q9UIV3
List of interactors in Reactome
Interactors (23)
Accession
#Entities
Reactome Entity
Confidence Score
Evidence (IntAct)
Q13546
4
K48polyUb-K571,K604,K627-RIPK1 [cytosol]
(R-HSA-9796639)
RIPK1 [cytosol]
(R-HSA-168651)
RIPK1 [plasma membrane]
(R-HSA-937073)
RIPK1(1-324) [cytosol]
(R-HSA-5212664)
0.837
9
Q12933
1
TRAF2 [cytosol]
(R-HSA-66370)
0.788
9
Q13490
3
BIRC2 [cytosol]
(R-HSA-50847)
BIRC2(1-372) [cytosol]
(R-HSA-202913)
BIRC2(373-618) [cytosol]
(R-HSA-202931)
0.788
5
P01375
3
TNF(1-34) [plasma membrane]
(R-HSA-8863367)
TNF(52-76) [extracellular region]
(R-HSA-8863375)
TNF(77-233) [extracellular region]
(R-HSA-976821)
0.73
3
Q15628
1
TRADD [cytosol]
(R-HSA-66376)
0.725
7
Q9H0F6
1
SHARPIN [cytosol]
(R-HSA-5212666)
0.725
4
Q9Y6K9
3
IKBKG [cytosol]
(R-HSA-168108)
IKBKG [nucleoplasm]
(R-HSA-4755413)
monoSUMO1-K277,K309-IKBKG [nucleoplasm]
(R-HSA-4755449)
0.669
3
P20333
1
TNFRSF1B [plasma membrane]
(R-HSA-5661484)
0.609
2
Q16623
1
STX1A [plasma membrane]
(R-HSA-449128)
0.601
4
Q60855
3
K48polyUb-K571,K604,K627-RIPK1 [cytosol]
(R-MMU-9796639)
RIPK1 [cytosol]
(R-MMU-168651)
RIPK1(1-324) [cytosol]
(R-MMU-5212664)
0.576
4
29108
12
Ca2+ [cytosol]
(R-ALL-74016)
Ca2+ [endoplasmic reticulum lumen]
(R-ALL-111875)
Ca2+ [endoplasmic reticulum-Golgi intermediate compartment]
(R-ALL-9706979)
Ca2+ [extracellular region]
(R-ALL-74112)
Ca2+ [Golgi lumen]
(R-ALL-167012)
Ca2+ [lysosomal lumen]
(R-ALL-1606834)
Ca2+ [mitochondrial intermembrane space]
(R-ALL-8949232)
Ca2+ [mitochondrial matrix]
(R-ALL-8949220)
Ca2+ [nucleoplasm]
(R-ALL-29496)
Ca2+ [plasma membrane]
(R-ALL-140648)
Ca2+ [platelet dense tubular network lumen]
(R-ALL-139827)
Ca2+ [sarcoplasmic reticulum lumen]
(R-ALL-2855229)
0.558
5
O15552
1
FFAR2 [plasma membrane]
(R-HSA-443944)
0.556
3
P05067
12
APP(18-671) [endosome lumen]
(R-HSA-5693003)
APP(18-687) [extracellular region]
(R-HSA-9010033)
APP(18-770) [endosome lumen]
(R-HSA-5229077)
APP(18-770) [plasma membrane]
(R-HSA-9010038)
APP(18-770) [trans-Golgi network membrane]
(R-HSA-5229136)
APP(672-711) [endosome lumen]
(R-HSA-6783333)
APP(672-713) [endosome lumen]
(R-HSA-5692993)
APP(672-713) [extracellular region]
(R-HSA-879340)
APP(672-770) [endosome lumen]
(R-HSA-9010082)
APP(688-770) [plasma membrane]
(R-HSA-9010028)
APP(712-770) [endosome lumen]
(R-HSA-6783331)
APP(714-770) [endosome lumen]
(R-HSA-6783325)
0.556
3
Q16585
1
SGCB [endoplasmic reticulum membrane]
(R-HSA-9913185)
0.556
3
Q8IUN9
1
CLEC10A [plasma membrane]
(R-HSA-1472863)
0.556
3
Q96BA8
7
CREB3L1 [endoplasmic reticulum membrane]
(R-HSA-8874157)
CREB3L1 [Golgi membrane]
(R-HSA-8874155)
CREB3L1(1-375) [cytosol]
(R-HSA-8874215)
CREB3L1(1-375) [nucleoplasm]
(R-HSA-8874222)
CREB3L1(1-426) [Golgi membrane]
(R-HSA-8874153)
CREB3L1(376-426) [Golgi membrane]
(R-HSA-8874213)
CREB3L1(427-519) [Golgi membrane]
(R-HSA-8874139)
0.556
3
Q9HC36
1
RNMTL1 [mitochondrial matrix]
(R-HSA-6793067)
0.556
3
P21580
1
TNFAIP3 [cytosol]
(R-HSA-688989)
0.527
2
Q14118
13
DAG1 [endoplasmic reticulum membrane]
(R-HSA-9913254)
DAG1(30-653) [cytosol]
(R-HSA-5615641)
DAG1(30-653) [endoplasmic reticulum lumen]
(R-HSA-8931890)
DAG1(30-653) [extracellular region]
(R-HSA-2328152)
DAG1(654-895) [endoplasmic reticulum membrane]
(R-HSA-9913257)
DAG1(654-895) [Golgi membrane]
(R-HSA-9913184)
GalNAc-GlcNAc-Man-DAG1 [endoplasmic reticulum lumen]
(R-HSA-8931656)
GalNAc-GlcNAc-Man6P-DAG1 [endoplasmic reticulum lumen]
(R-HSA-8931659)
GlcNAc,1,2-Man-DAG1 [Golgi lumen]
(R-HSA-5617087)
GlcNAc-1,6-(GlcNAc-1,2)-Man-DAG1 [Golgi lumen]
(R-HSA-8932424)
GlcNAc-Man-DAG1 [endoplasmic reticulum lumen]
(R-HSA-8931673)
Man-DAG1 [endoplasmic reticulum lumen]
(R-HSA-5615647)
Man-DAG1 [Golgi lumen]
(R-HSA-8931888)
0.527
2
O88351
2
IKBKB [cytosol]
(R-MMU-168114)
phospho-p-S177,S181-IKBKB [cytosol]
(R-MMU-202506)
0.499
3
O89110
1
Casp8 [cytosol]
(R-MMU-57031)
0.499
2
Q3U0V2
1
TRADD [cytosol]
(R-MMU-66376)
0.499
2
Q60769
1
TNFAIP3 [cytosol]
(R-MMU-688989)
0.499
2
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