Reactome | UniProt:P04049 RAF1

UniProt:P04049 RAF1

Type

Interactor (Protein)

Species

Homo sapiens

Synonyms

RAF1_HUMAN, B0LPH8, B2R5N3, Q15278, Q9UC20

List of interactors in Reactome

Interactors (31)

Accession	#Entities	Reactome Entity	Confidence Score	Evidence (IntAct)
P15056	3	BRAF [cytosol] (R-HSA-167224) hyperphosphorylated BRAF [plasma membrane] (R-HSA-5675199) p-S446,T599,S602,S729 BRAF [plasma membrane] (R-HSA-5672679)	0.966	72
P63104	2	YWHAZ [cytosol] (R-HSA-206099) YWHAZ [nucleoplasm] (R-HSA-450469)	0.966	35
Q02750	4	MAP2K1 [cytosol] (R-HSA-59502) MAP2K1(2-8) [cytosol] (R-HSA-5211342) MAP2K1(9-393) [cytosol] (R-HSA-5211353) p-S218,S222-MAP2K1 [cytosol] (R-HSA-109837)	0.96	39
P31946	1	YWHAB [cytosol] (R-HSA-48888)	0.955	38
P62258	1	YWHAE [cytosol] (R-HSA-194368)	0.913	24
P31947	1	SFN [cytosol] (R-HSA-1445105)	0.887	9
P08238	1	HSP90AB1 [cytosol] (R-HSA-419617)	0.857	17
P36507	4	MAP2K2 [cytosol] (R-HSA-59504) MAP2K2(1-10) [cytosol] (R-HSA-5211334) MAP2K2(11-400) [cytosol] (R-HSA-5211337) p-S,T-MAP2K2 [cytosol] (R-HSA-109848)	0.85	7
P04049	3	hyperphosphorylated RAF1 [plasma membrane] (R-HSA-5675193) p-S338,Y341,T491,S494,S621 RAF1 [plasma membrane] (R-HSA-5672665) RAF1 [cytosol] (R-HSA-167205)	0.811	6
P30086	1	PEBP1 [cytosol] (R-HSA-61487)	0.758	10
P07900	1	HSP90AA1 [cytosol] (R-HSA-192864)	0.744	15
P01116	2	p-Y32-S-Farn-Me-PalmS KRAS [plasma membrane] (R-HSA-9674821) S-Farn-Me-PalmS KRAS [plasma membrane] (R-HSA-9674814)	0.695	6
P01116	4	pS181-S-Farn-Me KRAS4B [mitochondrial outer membrane] (R-HSA-9653578) pS181-S-Farn-Me KRAS4B [plasma membrane] (R-HSA-9653482) S-Farn-Me KRAS4B [endoplasmic reticulum membrane] (R-HSA-9649690) S-Farn-Me KRAS4B [plasma membrane] (R-HSA-9647815)	0.676	3
Q13188	1	STK3(323-491) [cytosol] (R-HSA-2028684)	0.645	6
O43852	2	CALU [endoplasmic reticulum lumen] (R-HSA-350695) CALU [extracellular region] (R-HSA-350739)	0.643	4
Q13418	1	ILK [cytosol] (R-HSA-432864)	0.643	3
P11021	2	HSPA5 [endoplasmic reticulum membrane] (R-HSA-351315) HSPA5 [extracellular region] (R-HSA-351322)	0.576	5
Q6TCH7	1	PAQR3 [Golgi membrane] (R-HSA-5674103)	0.576	3
P32883	6	phospho-p-Y32-S-Farn-Me-PalmS KRAS [plasma membrane] (R-MMU-9674821) phospho-pS181-S-Farn-Me KRAS4B [mitochondrial outer membrane] (R-MMU-9653578) phospho-pS181-S-Farn-Me KRAS4B [plasma membrane] (R-MMU-9653482) S-Farn-Me KRAS4B [endoplasmic reticulum membrane] (R-MMU-9649690) S-Farn-Me KRAS4B [plasma membrane] (R-MMU-9647815) S-Farn-Me-PalmS KRAS4A [plasma membrane] (R-MMU-9647915)	0.573	2
Q13526	2	PIN1 [cytosol] (R-HSA-9626823) PIN1 [nucleoplasm] (R-HSA-936016)	0.564	2
Q9UNE7	1	STUB1 [cytosol] (R-HSA-975970)	0.564	8
Q13177	9	K48polyUb-p-T402-PAK-2p43 [cytosol] (R-HSA-3095873) p-5S-PAK2 [cytosol] (R-HSA-211609) p-5S-PAK2(2-212) [cytosol] (R-HSA-211588) p-S141,T402-PAK2 [cytosol] (R-HSA-399824) p-T402-PAK2(213-524) [cytosol] (R-HSA-211654) p-T402-PAK2(213-524) [nucleoplasm] (R-HSA-211709) PAK2 [cytosol] (R-HSA-211604) PAK2(1-524) [plasma membrane] (R-HSA-164946) PAK2(213-524) [cytosol] (R-HSA-211653)	0.558	2
P05067	12	APP(18-671) [endosome lumen] (R-HSA-5693003) APP(18-687) [extracellular region] (R-HSA-9010033) APP(18-770) [endosome lumen] (R-HSA-5229077) APP(18-770) [plasma membrane] (R-HSA-9010038) APP(18-770) [trans-Golgi network membrane] (R-HSA-5229136) APP(672-711) [endosome lumen] (R-HSA-6783333) APP(672-713) [endosome lumen] (R-HSA-5692993) APP(672-713) [extracellular region] (R-HSA-879340) APP(672-770) [endosome lumen] (R-HSA-9010082) APP(688-770) [plasma membrane] (R-HSA-9010028) APP(712-770) [endosome lumen] (R-HSA-6783331) APP(714-770) [endosome lumen] (R-HSA-6783325)	0.556	3
Q14790	4	CASP8(1-479) [cytosol] (R-HSA-57031) CASP8(217-374) [cytosol] (R-HSA-75975) CASP8(375-384) [cytosol] (R-HSA-933460) CASP8(385-479) [cytosol] (R-HSA-76158)	0.556	3
P00533	2	EGFR [plasma membrane] (R-HSA-179837) EGFRvIII [plasma membrane] (R-HSA-1214162)	0.553	2
P67775	1	PPP2CA [cytosol] (R-HSA-165971)	0.544	2
P31749	8	AKT1 [cytosol] (R-HSA-58252) AKT1 E17K [cytosol] (R-HSA-2219526) p-S473-AKT1 [cytosol] (R-HSA-9841264) p-T308,S473-AKT1 [cytosol] (R-HSA-198356) p-T308,S473-AKT1 [nucleoplasm] (R-HSA-198357) p-T308,S473-AKT1 [plasma membrane] (R-HSA-199430) p-T308,S473-AKT1 E17K [cytosol] (R-HSA-2243935) p-T308,S473-AKT1 E17K [nucleoplasm] (R-HSA-2399994)	0.536	2
P17987	1	TCP1 [cytosol] (R-HSA-390448)	0.527	5
Q8N163	2	DBC1 [nucleoplasm] (R-HSA-3371479) p-T454-DBC1 [nucleoplasm] (R-HSA-3371569)	0.527	9
Q9ULX6	1	AKAP8L [nucleoplasm] (R-HSA-9821364)	0.527	9
P43246	1	MSH2 [nucleoplasm] (R-HSA-5357525)	0.508	2

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