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UniProt:P04626 ERBB2
Type
Interactor (Protein)
Species
Homo sapiens
Synonyms
ERBB2_HUMAN, B2RZG3, B4DHN3, Q14256, Q6LDV1, Q9UMK4, X5D2V5
List of interactors in Reactome
Interactors (36)
Accession
#Entities
Reactome Entity
Confidence Score
Evidence (IntAct)
P00533
2
EGFR [plasma membrane]
(R-HSA-179837)
EGFRvIII [plasma membrane]
(R-HSA-1214162)
0.954
25
P04626
1
ERBB2 [plasma membrane]
(R-HSA-372889)
0.926
12
P62993
1
GRB2 [cytosol]
(R-HSA-8983328)
0.916
8
P07900
1
HSP90AA1 [cytosol]
(R-HSA-192864)
0.856
6
P29353
2
p-Y427-SHC1 [cytosol]
(R-HSA-74684)
SHC1 [cytosol]
(R-HSA-74680)
0.821
16
P08238
1
HSP90AB1 [cytosol]
(R-HSA-419617)
0.793
5
Q14451
1
GRB7 [cytosol]
(R-HSA-204819)
0.779
5
P40763
6
p-S727-STAT3 [cytosol]
(R-HSA-198705)
p-STAT3 [cytosol]
(R-HSA-8982823)
p-Y705,S727-STAT3 [cytosol]
(R-HSA-539048)
p-Y705-STAT3 [cytosol]
(R-HSA-8983130)
p-Y705-STAT3 [cytosol]
(R-HSA-914048)
STAT3 [cytosol]
(R-HSA-539044)
0.775
9
P27986
1
PIK3R1 [cytosol]
(R-HSA-74789)
0.759
12
Q96JA1
1
LRIG1 [plasma membrane]
(R-HSA-197745)
0.748
7
P12931
5
MyrG-p-Y419-SRC [plasma membrane]
(R-HSA-1810408)
MyrG-SRC [plasma membrane]
(R-HSA-8876922)
p-Y419-SRC [cytosol]
(R-HSA-8964276)
p-Y419-SRC [nucleoplasm]
(R-HSA-8937690)
SRC [cytosol]
(R-HSA-9628701)
0.708
11
P11021
2
HSPA5 [endoplasmic reticulum membrane]
(R-HSA-351315)
HSPA5 [extracellular region]
(R-HSA-351322)
0.659
3
Q13882
4
p-Y342,Y447-PTK6 [cytosol]
(R-HSA-8849103)
p-Y342-PTK6 [cytosol]
(R-HSA-8848007)
p-Y342-PTK6 [nucleoplasm]
(R-HSA-8848937)
PTK6 [cytosol]
(R-HSA-8848000)
0.628
4
P46940
1
IQGAP1 [plasma membrane]
(R-HSA-381681)
0.602
5
P20936
1
RASA1 [cytosol]
(R-HSA-186833)
0.592
8
Q05209
1
PTPN12 [cytosol]
(R-HSA-432933)
0.592
4
Q06124
2
PTPN11 [cytosol]
(R-HSA-162563)
PTPN11 [nucleoplasm]
(R-HSA-8937745)
0.592
3
P42679
1
MATK [cytosol]
(R-HSA-1433581)
0.59
2
P31948
1
STIP1 [cytosol]
(R-HSA-443857)
0.573
2
O75791
1
GRAP2 [cytosol]
(R-HSA-202367)
0.571
2
P16885
5
p-PLCG2 [plasma membrane]
(R-HSA-114602)
p-Y753,Y759-PLCG2 [cytosol]
(R-HSA-5607631)
p-Y753,Y759-PLCG2 [plasma membrane]
(R-HSA-5607640)
PLCG2 [cytosol]
(R-HSA-984806)
PLCG2 [plasma membrane]
(R-HSA-114601)
0.571
3
P42224
4
p-STAT1 [cytosol]
(R-HSA-8950418)
p-Y701-STAT1 [cytosol]
(R-HSA-8951202)
p-Y701-STAT1 [cytosol]
(R-HSA-3132766)
STAT1 [cytosol]
(R-HSA-629622)
0.571
3
P27824
1
CANX [endoplasmic reticulum lumen]
(R-HSA-195906)
0.569
3
O95602
1
POLR1A [nucleoplasm]
(R-HSA-63494)
0.567
16
Q14974
2
KPNB1 [cytosol]
(R-HSA-180733)
KPNB1 [nucleoplasm]
(R-HSA-180714)
0.567
14
O14980
2
XPO1 [cytosol]
(R-HSA-165539)
XPO1 [nucleoplasm]
(R-HSA-165529)
0.564
3
P06241
3
FYN [cytosol]
(R-HSA-200917)
p-Y420-FYN [cytosol]
(R-HSA-391821)
p-Y531-FYN [cytosol]
(R-HSA-391819)
0.558
2
Q99952
1
PTPN18 [cytosol]
(R-HSA-8864101)
0.558
6
Q9UBN7
2
HDAC6 [cytosol]
(R-HSA-5324660)
HDAC6 [nucleoplasm]
(R-HSA-351589)
0.553
2
P60709
2
ACTB [cytosol]
(R-HSA-201861)
ACTB [nucleoplasm]
(R-HSA-3321990)
0.537
10
Q05397
5
p-Y397-PTK2 [cytosol]
(R-HSA-354068)
PTK2 [cytosol]
(R-HSA-201621)
PTK2(1-772) [cytosol]
(R-HSA-202827)
PTK2(773-1052) [cytosol]
(R-HSA-202829)
pY-PTK2 [cytosol]
(R-HSA-9632393)
0.536
2
P31689
2
DNAJA1 [cytosol]
(R-HSA-3371544)
SOH-C149,C150-DNAJA1 [cytosol]
(R-HSA-9857072)
0.527
2
P37173
2
NEDD8-K556,K567-TGFBR2 [plasma membrane]
(R-HSA-4332222)
TGFBR2 [plasma membrane]
(R-HSA-170842)
0.527
3
Q92504
1
SLC39A7 [endoplasmic reticulum membrane]
(R-HSA-442363)
0.527
2
Q9BVV7
1
TIMM21 [mitochondrial intermembrane space]
(R-HSA-9865416)
0.527
2
P49792
3
monoSUMO1-K2592,K2650,K2723-RANBP2 [nuclear envelope]
(R-HSA-4551599)
polySUMO2-K2652,K2725-RANBP2 [nuclear envelope]
(R-HSA-4551720)
RANBP2 [nuclear envelope]
(R-HSA-2993756)
0.463
3
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