Reactome | UniProt:P11387 TOP1

UniProt:P11387 TOP1

Type

Interactor (Protein)

Species

Homo sapiens

Synonyms

TOP1_HUMAN, A8KA78, E1P5W3, O43256, Q12855, Q12856, Q15610, Q5TFY3, Q9UJN0

List of interactors in Reactome

Interactors (25)

Accession	#Entities	Reactome Entity	Confidence Score	Evidence (IntAct)
P01106	1	MYC [nucleoplasm] (R-HSA-188379)	0.669	3
P00519	5	ABL1 [cytosol] (R-HSA-375987) ABL1 [nucleoplasm] (R-HSA-5686579) p-S456-ABL1 [nucleoplasm] (R-HSA-5686576) p-Y226,Y393-ABL1 [nucleoplasm] (R-HSA-8985251) p-Y393-ABL1 [cytosol] (R-HSA-9865161)	0.602	7
P07910	2	HNRNPC [nucleoplasm] (R-HSA-71933) SUMO1-K250-HNRNPC [nucleoplasm] (R-HSA-4570543)	0.597	4
P09651	2	HNRNPA1 [cytosol] (R-HSA-9727902) HNRNPA1 [nucleoplasm] (R-HSA-71927)	0.597	4
P09874	3	monoSUMO1-K203,K486-PARP1 [nucleoplasm] (R-HSA-4551686) PARP1 [nucleoplasm] (R-HSA-201568) polySUMO2,3-K203,K486-PARP1 [nucleoplasm] (R-HSA-4551617)	0.597	5
P11388	3	monoSUMO1-K-TOP2A [nucleoplasm] (R-HSA-4641367) polySUMO2,3-TOP2A [nucleoplasm] (R-HSA-4641298) TOP2A [nucleoplasm] (R-HSA-1362276)	0.597	4
P22626	1	HNRNPA2B1 [extracellular exosome] (R-HSA-8950304)	0.597	4
P23246	3	p-Y-SFPQ [nucleoplasm] (R-HSA-8849461) SFPQ [cytosol] (R-HSA-9635505) SFPQ [nucleoplasm] (R-HSA-3900138)	0.597	3
P61978	2	HNRNPK [nucleoplasm] (R-HSA-71945) polySUMO2-K422-HNRNPK [nucleoplasm] (R-HSA-4570532)	0.597	3
P78527	4	K48polyUb-PRKDC [cytosol] (R-HSA-8938766) p-T2609,S2612,T2638,T2647-PRKDC [nucleoplasm] (R-HSA-76302) PRKDC [cytosol] (R-HSA-3134816) PRKDC [nucleoplasm] (R-HSA-62161)	0.597	3
Q00839	1	HNRNPU [nucleoplasm] (R-HSA-71953)	0.597	4
Q08211	3	DHX9 [cytosol] (R-HSA-847700) DHX9 [nucleoplasm] (R-HSA-53517) p-DHX9 [cytosol] (R-HSA-9836168)	0.597	4
Q15717	3	ELAVL1 [nucleoplasm] (R-HSA-450601) p-S158,S221-ELAVL1 [nucleoplasm] (R-HSA-450576) p-S221,S318-ELAVL1 [nucleoplasm] (R-HSA-450532)	0.597	4
Q92841	2	DDX17 [nucleoplasm] (R-HSA-3900090) monoSUMO1-K50-DDX17 [nucleoplasm] (R-HSA-3900104)	0.597	4
Q9NR30	1	DDX21 [nucleoplasm] (R-HSA-5250652)	0.597	4
P19338	2	NCL [nucleoplasm] (R-HSA-6791213) NCL [plasma membrane] (R-HSA-9836466)	0.59	3
P42768	1	WAS [cytosol] (R-HSA-201879)	0.558	3
P17844	4	DDX5 [cytosol] (R-HSA-9682643) DDX5 [nucleoplasm] (R-HSA-3900136) monoSUMO1-K53-DDX5 [nucleoplasm] (R-HSA-3900041) polySUMO2-K53-DDX5 [nucleoplasm] (R-HSA-3900186)	0.527	3
P19320	1	VCAM1 [plasma membrane] (R-HSA-197834)	0.527	4
Q96JC9	1	EAF1 [nucleoplasm] (R-HSA-8932787)	0.527	2
Q9BUQ8	1	DDX23 [nucleoplasm] (R-HSA-71879)	0.527	2
P03372	2	ESR1 [nucleoplasm] (R-HSA-446168) monoSUMO1-5K-ESR1 [nucleoplasm] (R-HSA-4090302)	0.462	2
P06748	6	monoSUMO1-K263-NPM1 [nucleoplasm] (R-HSA-4086039) NPM1 [cytosol] (R-HSA-3008211) NPM1 [granular component] (R-HSA-9017702) NPM1 [nucleoplasm] (R-HSA-606320) p-S4-NPM1 [cytosol] (R-HSA-6801679) polySUMO2,3-K263-NPM1 [nucleoplasm] (R-HSA-4086056)	0.462	3
P09661	1	SNRPA1 [nucleoplasm] (R-HSA-71958)	0.462	2
Q07955	1	SRSF1 [nucleoplasm] (R-HSA-72031)	0.462	3