Reactome | UniProt:P13569 CFTR

UniProt:P13569 CFTR

Type

Interactor (Protein)

Species

Homo sapiens

Synonyms

CFTR_HUMAN, Q20BG8, Q20BH2, Q2I0A1, Q2I102

List of interactors in Reactome

Interactors (58)

Accession	#Entities	Reactome Entity	Confidence Score	Evidence (IntAct)
P27824	1	CANX [endoplasmic reticulum lumen] (R-HSA-195906)	0.813	14
P13569	5	CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) CFTR G551D [plasma membrane] (R-HSA-5678977) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.702	12
P60709	2	ACTB(1-375) [cytosol] (R-HSA-201861) ACTB(1-375) [nucleoplasm] (R-HSA-3321990)	0.669	5
P02545	1	LMNA(1-646) [nuclear envelope] (R-HSA-535479)	0.643	13
P11021	2	HSPA5 [endoplasmic reticulum membrane] (R-HSA-351315) HSPA5 [extracellular region] (R-HSA-351322)	0.643	11
P13987	1	CD59 [plasma membrane] (R-HSA-2530458)	0.643	9
Q14974	2	KPNB1 [cytosol] (R-HSA-180733) KPNB1 [nucleoplasm] (R-HSA-180714)	0.643	11
Q15369	2	ELOC [cytosol] (R-HSA-180535) TCEB1 [nucleoplasm] (R-HSA-112422)	0.643	7
Q15370	2	ELOB [cytosol] (R-HSA-180551) TCEB2 [nucleoplasm] (R-HSA-112423)	0.643	12
O15554	1	KCNN4 [plasma membrane] (R-HSA-977543)	0.602	5
P15311	1	EZR [cytosol] (R-HSA-9020826)	0.597	10
O00410	1	IPO5 [nucleoplasm] (R-HSA-192675)	0.527	4
O14980	2	XPO1 [cytosol] (R-HSA-165539) XPO1 [nucleoplasm] (R-HSA-165529)	0.527	12
O43852	2	CALU [endoplasmic reticulum lumen] (R-HSA-350695) CALU [extracellular region] (R-HSA-350739)	0.527	2
P04637	2	polySUMO2,3-K386-TP53 [nucleoplasm] (R-HSA-2997661) TP53 [nucleoplasm] (R-HSA-69488)	0.527	10
P04792	3	HSPB1 [cytosol] (R-HSA-450563) p-S15,S78,S82-HSP27 [cytosol] (R-HSA-5218697) p-S78,S82 HSPB1 [cytosol] (R-HSA-5687009)	0.527	9
P05121	1	SERPINE1 [extracellular region] (R-HSA-158797)	0.527	10
P06733	1	ENO1 [cytosol] (R-HSA-71437)	0.527	9
P06748	6	monoSUMO1-K263-NPM1 [nucleoplasm] (R-HSA-4086039) NPM1 [cytosol] (R-HSA-3008211) NPM1 [granular component] (R-HSA-9017702) NPM1 [nucleoplasm] (R-HSA-606320) p-S4-NPM1 [cytosol] (R-HSA-6801679) polySUMO2,3-K263-NPM1 [nucleoplasm] (R-HSA-4086056)	0.527	10
P07910	2	HNRNPC [nucleoplasm] (R-HSA-71933) SUMO1-K250-HNRNPC [nucleoplasm] (R-HSA-4570543)	0.527	6
P07947	1	YES1 [cytosol] (R-HSA-373640)	0.527	6
P08238	1	HSP90AB1 [cytosol] (R-HSA-419617)	0.527	11
P10809	1	HSPD1 [mitochondrial matrix] (R-HSA-1299448)	0.527	10
P12004	2	monoSUMO1-K164,K254,K-PCNA [nucleoplasm] (R-HSA-4615861) PCNA [nucleoplasm] (R-HSA-68439)	0.527	10
P14174	1	MIF [secretory granule lumen] (R-HSA-6803282)	0.527	9
P17987	1	TCP1 [cytosol] (R-HSA-390448)	0.527	9
P19474	1	TRIM21 [cytosol] (R-HSA-976051)	0.527	10
P20700	5	LMNB1 [nucleoplasm] (R-HSA-264867) LMNB1(1-231) [nuclear envelope] (R-HSA-352244) LMNB1(2-586) [nuclear envelope] (R-HSA-912402) LMNB1(232-586) [nuclear envelope] (R-HSA-352248) p-S23,S393-LMNB1 [nucleoplasm] (R-HSA-8868341)	0.527	10
P22061	1	PCMT1 [cytosol] (R-HSA-5676580)	0.527	11
P22626	1	HNRNPA2B1 [extracellular exosome] (R-HSA-8950304)	0.527	10
P23246	3	p-Y-SFPQ [nucleoplasm] (R-HSA-8849461) SFPQ [cytosol] (R-HSA-9635505) SFPQ [nucleoplasm] (R-HSA-3900138)	0.527	10
P26599	1	PTBP1 [nucleoplasm] (R-HSA-71923)	0.527	7
P26641	1	EEF1G [cytosol] (R-HSA-156925)	0.527	10
P32119	2	p-T89-PRDX2 [cytosol] (R-HSA-8868574) PRDX2 [cytosol] (R-HSA-3341292)	0.527	9
P35232	1	PHB [cytosol] (R-HSA-5672944)	0.527	9
P35579	1	MYH9 [cytosol] (R-HSA-419173)	0.527	9
P38646	2	HSPA9 [mitochondrial matrix] (R-HSA-8878802) HSPA9(1-679) [mitochondrial intermembrane space] (R-HSA-1267968)	0.527	11
P43490	1	NAMPT [cytosol] (R-HSA-197188)	0.527	10
P47897	1	QARS [mitochondrial matrix] (R-HSA-379592)	0.527	8
P49023	3	p-Y31,Y118-PXN [cytosol] (R-HSA-5218693) PXN [cytosol] (R-HSA-210014) PXN [plasma membrane] (R-HSA-180493)	0.527	9
P50454	1	SERPINH1 [endoplasmic reticulum lumen] (R-HSA-2127480)	0.527	10
P52597	1	HNRNPF [plasma membrane] (R-HSA-8950714)	0.527	2
P54652	1	HSPA2 [nucleoplasm] (R-HSA-912480)	0.527	4
P55072	2	Me3K315-VCP [cytosol] (R-HSA-8932209) VCP [cytosol] (R-HSA-1181251)	0.527	7
P61978	2	HNRNPK [nucleoplasm] (R-HSA-71945) polySUMO2-K422-HNRNPK [nucleoplasm] (R-HSA-4570532)	0.527	10
P63000	1	RAC1 [cytosol] (R-HSA-442615)	0.527	9
P63104	2	YWHAZ [cytosol] (R-HSA-206099) YWHAZ [nucleoplasm] (R-HSA-450469)	0.527	10
P63244	1	GNB2L1 [cytosol] (R-HSA-5626956)	0.527	9
P67809	2	p-S32,S36-YBX1 [nucleoplasm] (R-HSA-9733227) YBX1 [extracellular region] (R-HSA-9017791)	0.527	10
P78527	4	K48polyUb-PRKDC [cytosol] (R-HSA-8938766) p-T2609,S2612,T2638,T2647-PRKDC [nucleoplasm] (R-HSA-76302) PRKDC [cytosol] (R-HSA-3134816) PRKDC [nucleoplasm] (R-HSA-62161)	0.527	10
Q06830	2	p-T90-PRDX1 [cytosol] (R-HSA-8868564) PRDX1 [cytosol] (R-HSA-3341270)	0.527	10
Q08211	2	DHX9 [cytosol] (R-HSA-847700) DHX9 [nucleoplasm] (R-HSA-53517)	0.527	10
Q08J23	1	NSUN2 [nucleoplasm] (R-HSA-6782382)	0.527	9
Q14498	1	RBM39 [nucleoplasm] (R-HSA-9770254)	0.527	10
Q9UL46	1	PSME2 [nucleoplasm] (R-HSA-174350)	0.527	9
Q9UN37	1	VPS4A [cytosol] (R-HSA-917732)	0.527	2
P51572	4	BCAP31(165-237) [endoplasmic reticulum membrane] (R-HSA-351909) BCAP31(2-164) [endoplasmic reticulum membrane] (R-HSA-351826) BCAP31(2-245) [endoplasmic reticulum membrane] (R-HSA-201587) BCAP31(238-246) [cytosol] (R-HSA-351912)	0.463	3
Q5XXA6	1	ANO1 [plasma membrane] (R-HSA-2684927)	0.463	2